| URN | urn:agi-llid:6822 |
|---|---|
| Connectivity | 77 |
| Name | Sult2a1 |
| Description | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| Notes | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene is primarily expressed in liver and adrenal tissues where the encoded protein sulfates steroids and bile acids. [provided by RefSeq] |
| Pathway | testosterone biosynthetic pathway - gth |
|---|---|
| Copy of 'testosterone biosynthetic pathway' | |
| testosterone biosynthetic pathway | |
| testosterone biosynthetic pathway - Copy | |
| tamoxifen pharmacokinetics pathway | |
| estradiol biosynthetic pathway | |
| testosterone biosynthetic pathway |
| GO Molecular Function | drug binding |
|---|---|
| transferase activity | |
| sulfotransferase activity | |
| bile-salt sulfotransferase activity | |
| alcohol sulfotransferase activity |
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol |
| GO Biological Process | aging |
|---|---|
| digestion | |
| response to activity | |
| cellular response to vitamin D | |
| bile acid catabolic process | |
| response to insecticide | |
| response to nutrient levels | |
| lipid metabolic process | |
| steroid metabolic process |
| Ariadne Ontology | Steroid metabolism |
|---|
| Group | Steroid metabolism |
|---|---|
| aging | |
| digestion | |
| response to activity | |
| cellular response to vitamin D | |
| bile acid catabolic process | |
| response to insecticide | |
| response to nutrient levels | |
| lipid metabolic process | |
| steroid metabolic process | |
| drug binding | |
| transferase activity | |
| sulfotransferase activity | |
| bile-salt sulfotransferase activity | |
| alcohol sulfotransferase activity | |
| cytoplasm | |
| cytosol |
| MedScan ID | 6822 |
|---|
| Hugo ID | 11458 |
|---|
| Human chromosome position | 19q13.3 |
|---|
| LocusLink ID | 6822 |
|---|---|
| 20859 | |
| 24912 |
| Alias | HST |
|---|---|
| ST2 | |
| STD | |
| hSTa | |
| DHEAS | |
| ST2A1 | |
| ST2A3 | |
| DHEA-ST | |
| bile salt sulfotransferase | |
| bile-salt sulfotranasferase 2A1 | |
| alcohol/hydroxysteroid sulfotransferase | |
| Sth1 | |
| mSTa1 | |
| bile salt sulfotransferase 1 | |
| ST | |
| sulfotransferase 2A1 | |
| hydroxysteroid sulfotransferase | |
| sulfotransferase, DHEA preferring | |
| sulfotransferase, hydroxysteroid preferring 1 | |
| STa | |
| Sth2 | |
| Smp-2 | |
| ST-20 | |
| alcohol sulfotransferase | |
| bile-salt sulfotransferase 2A1 | |
| hydroxysteroid sulfotransferase a | |
| sulfotransferase hydroxysteroid gene 2 | |
| sulfotransferase, hydroxysteroid preferring 2 | |
| sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1 | |
| Sta1 | |
| cytosolic sulfotransferase family, 2A, dehydroepiandrosterone (DHEA)-preferring | |
| Dehydroepiandrosterone sulfotransferase | |
| DHEA-STs | |
| mSTa I | |
| mSTa2 | |
| Rat senescence marker 2A gene, exons 1 and | |
| RATSMP2A | |
| RATSMP2B | |
| Smp II | |
| Smp2a | |
| Sth I | |
| sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | |
| sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | |
| sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone-preferring, member 1 | |
| Sulfotransferase hydroxysteroid gene 1 | |
| Sulfotransferase hydroxysteroid gene I | |
| Sulfotransferase hydroxysteroid gene II | |
| sulfotransferase, hydroxysteroid preferring | |
| sulfotransferase, hydroxysteroid preferring I | |
| sulfotransferase, hydroxysteroid preferring II | |
| sulfotransferase:ISOTYPE a I | |
| sulfotransferase:ISOTYPE a1 | |
| Sult2a I | |
| SULT2A1 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 125263 |
|---|
| Mouse chromosome position | 7 4.0 cM |
|---|
| GO ID | 0047704 |
|---|---|
| 0008146 | |
| 0016740 | |
| 0030573 | |
| 0007586 | |
| 0008202 | |
| 0005737 | |
| 0005829 | |
| 0006629 | |
| 0004027 | |
| 0008144 | |
| 0007568 | |
| 0071305 | |
| 0014823 | |
| 0017085 | |
| 0031667 |
| Rat chromosome position | 1q21.3-q22.1 |
|---|
| Swiss-Prot Accession | A8K015 |
|---|---|
| Q06520 | |
| P52843 | |
| P15709 |
| PIR ID | A33569 |
|---|---|
| I52849 | |
| I53037 |
| Unigene ID | Hs.515835 |
|---|---|
| Mm.260026 | |
| Rn.91378 | |
| Rn.92406 |
| KEGG ID | hsa:6822 |
|---|---|
| mmu:20859 | |
| rno:24912 |
| EC Number | 2.8.2.14 |
|---|---|
| 2.8.2.2 |
| Swiss-Prot ID | ST2A1_RAT |
|---|---|
| ST2A1_HUMAN | |
| ST2A1_MOUSE | |
| A8K015_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| Mitochondria |
| IPI ID | IPI00365461 |
|---|---|
| IPI00216133 | |
| IPI00131483 | |
| IPI00209474 |
| Homologene ID | 37741 |
|---|
| RGD ID | 621337 |
|---|
| MGI ID | 98430 |
|---|