| URN | urn:agi-llid:3283 |
|---|---|
| Connectivity | 185 |
| Name | Hsd3b1 |
| Description | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| Pathway | steroid hormone biosynthetic pathway |
|---|---|
| Copy of 'testosterone biosynthetic pathway' | |
| testosterone biosynthetic pathway | |
| estradiol biosynthetic pathway | |
| aldosterone biosynthetic pathway | |
| cortisol biosynthetic pathway | |
| Copy of 'steroid hormone biosynthetic pathway' | |
| Copy of 'steroid hormone biosynthetic pathway' | |
| Copy of 'steroid hormone biosynthetic pathway' | |
| testosterone biosynthetic pathway - Copy |
| GO Molecular Function | catalytic activity |
|---|---|
| isomerase activity | |
| oxidoreductase activity | |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity | |
| steroid delta-isomerase activity |
| GO Cellular Component | membrane |
|---|---|
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| mitochondrion | |
| mitochondrial inner membrane | |
| mitochondrial intermembrane space | |
| smooth endoplasmic reticulum membrane | |
| microsome | |
| integral to membrane |
| GO Biological Process | metabolic process |
|---|---|
| oxidation reduction | |
| androgen biosynthetic process | |
| estrogen biosynthetic process | |
| steroid biosynthetic process |
| Ariadne Ontology | Steroid metabolism |
|---|
| Group | Steroid metabolism |
|---|---|
| catalytic activity | |
| metabolic process | |
| oxidation reduction | |
| androgen biosynthetic process | |
| estrogen biosynthetic process | |
| steroid biosynthetic process | |
| isomerase activity | |
| oxidoreductase activity | |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity | |
| steroid delta-isomerase activity | |
| membrane | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| mitochondrion | |
| mitochondrial inner membrane | |
| mitochondrial intermembrane space | |
| smooth endoplasmic reticulum membrane | |
| microsome | |
| integral to membrane |
| MedScan ID | 3283 |
|---|
| Hugo ID | 5217 |
|---|
| Human chromosome position | 1p13.1 |
|---|
| LocusLink ID | 3283 |
|---|---|
| 15493 | |
| 15497 |
| Alias | I |
|---|---|
| HSD3B | |
| HSDB3 | |
| HSDB3A | |
| SDR11E1 | |
| 3BETAHSD | |
| RP5-920G3.4 | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | |
| 3-beta-HSD I | |
| progesterone reductase | |
| steroid Delta-isomerase | |
| trophoblast antigen FDO161G | |
| delta-5-3-ketosteroid isomerase | |
| 3-beta-hydroxy-5-ene steroid dehydrogenase | |
| 3-beta-hydroxy-Delta(5)-steroid dehydrogenase | |
| short chain dehydrogenase/reductase family 11E, member 1 | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I | |
| hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 | |
| RP23-112E4.3 | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 | |
| 3-beta-HSD II | |
| OTTMUSP00000007145 | |
| OTTMUSP00000007146 | |
| 3 beta-hydroxysteroid dehydrogenase 2 | |
| hydroxysteroid dehydrogenase-2, delta<5>-3-beta | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II | |
| D19210 | |
| RP23-112E4.5 | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6 | |
| 3beta-HSD VI | |
| 3-beta-HSD VI | |
| OTTMUSP00000007181 | |
| hydroxysteroid dehydrogenase-6, delta<5>-3-beta | |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type VI | |
| 3 beta-hydroxysteroid dehydrogenase/delta 5,4-isomerase type I | |
| 3(beta)HSDV | |
| 3Beta-HSD I | |
| 3beta-HSDH | |
| 3beta-hydroxy steroid dehydrogenase/isomerase | |
| 3beta-hydroxy-5-ene steroid dehydrogenase | |
| 3beta-hydroxy-5-ene-steroid oxidoreductase | |
| 3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase | |
| 3beta-hydroxy-delta5-steroid dehydrogenase | |
| 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase | |
| 5-ene-3-beta-hydroxysteroid dehydrogenase | |
| cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase | |
| cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenases | |
| D3Ertd383e | |
| delta5-3beta-hydroxysteroid dehydrogenase | |
| HSD 3B | |
| HSD(3)B | |
| HSD-3B | |
| HSD3-B | |
| Hsd3b I | |
| Hsd3b1 | |
| Hsd3b6 | |
| HSDB 3 | |
| HSDB(3) | |
| HSDB-3 | |
| Hydroxy-delta-5-steroid dehydrogenase 1 | |
| Hydroxy-delta-5-steroid dehydrogenase 3 beta- and steroid delta-isomerase | |
| Hydroxy-delta-5-steroid dehydrogenase I | |
| hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | |
| hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 | |
| hydroxysteroid dehydrogenase-1, delta 5-3-beta | |
| hydroxysteroid dehydrogenase-6, delta5,3-beta | |
| LOC365887 | |
| MGC109236 | |
| RATHSDI | |
| RATHSDIs | |
| steroid-delta5-3beta-ol dehydrogenase |
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| OMIM ID | 109715 |
|---|
| Mouse chromosome position | 3 49.1 cM |
|---|---|
| 3 |
| GO ID | 0003854 |
|---|---|
| 0016853 | |
| 0016491 | |
| 0004769 | |
| 0006702 | |
| 0006703 | |
| 0055114 | |
| 0006694 | |
| 0005783 | |
| 0005789 | |
| 0016021 | |
| 0016020 | |
| 0005792 | |
| 0005743 | |
| 0005758 | |
| 0005739 | |
| 0030868 | |
| 0003824 | |
| 0008152 |
| Swiss-Prot Accession | P14060 |
|---|---|
| Q5TDG2 | |
| B1ARN7 | |
| P26149 | |
| Q3UQN7 | |
| Q7TPU0 | |
| O35469 | |
| Q541Q1 | |
| Q76CU3 | |
| A8K691 | |
| Q14545 | |
| Q8IV65 |
| PIR ID | A36551 |
|---|
| Unigene ID | Hs.364941 |
|---|---|
| Mm.158717 | |
| Mm.14435 |
| KEGG ID | hsa:3283 |
|---|---|
| mmu:15493 | |
| mmu:15497 |
| EC Number | 1.1.1.145 |
|---|---|
| 5.3.3.1 |
| Swiss-Prot ID | 3BHS1_HUMAN |
|---|---|
| B1ARN7_MOUSE | |
| Q7TPU0_MOUSE | |
| Q3UQN7_MOUSE | |
| 3BHS4_RAT |
| Cell Localization | Endoplasmic reticulum membrane |
|---|---|
| Mitochondrion membrane | |
| Mitochondria |
| IPI ID | IPI00843838 |
|---|---|
| IPI00889871 | |
| IPI00882271 | |
| IPI00246994 | |
| IPI00420666 | |
| IPI00230105 | |
| IPI00555268 | |
| IPI00777087 |
| RGD ID | 67377 |
|---|
| MGI ID | 96234 |
|---|---|
| 109598 |