| URN | urn:agi-llid:10449 |
|---|---|
| Connectivity | 9 |
| Name | Acaa2 |
| Description | acetyl-Coenzyme A acyltransferase 2 |
| Notes | The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. |
| Pathway | fatty acid beta degradation pathway |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| transferase activity | |
| transferase activity, transferring acyl groups other than amino-acyl groups | |
| acyltransferase activity | |
| acetyl-CoA C-acyltransferase activity |
| GO Cellular Component | mitochondrion |
|---|---|
| mitochondrial inner membrane | |
| mitochondrial matrix |
| GO Biological Process | metabolic process |
|---|---|
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| acetyl-CoA metabolic process | |
| lipid metabolic process | |
| cholesterol biosynthetic process |
| Ariadne Ontology | Branched amino acid metabolism |
|---|---|
| Fatty acid oxidation |
| Group | Branched amino acid metabolism |
|---|---|
| Fatty acid oxidation | |
| catalytic activity | |
| metabolic process | |
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| acetyl-CoA metabolic process | |
| lipid metabolic process | |
| cholesterol biosynthetic process | |
| transferase activity | |
| transferase activity, transferring acyl groups other than amino-acyl groups | |
| acyltransferase activity | |
| acetyl-CoA C-acyltransferase activity | |
| mitochondrion | |
| mitochondrial inner membrane | |
| mitochondrial matrix |
| MedScan ID | 10449 |
|---|
| Hugo ID | 83 |
|---|
| Human chromosome position | 18q21.1 |
|---|
| LocusLink ID | 10449 |
|---|---|
| 52538 | |
| 170465 |
| Alias | DSAEC |
|---|---|
| FLJ35992 | |
| FLJ95265 | |
| 3-ketoacyl-CoA thiolase, mitochondrial | |
| T1 | |
| beta ketothiolase | |
| beta-ketothiolase | |
| acetyl-Coenzyme A acyltransferase 2 | |
| mitochondrial 3-oxoacyl-CoA thiolase | |
| mitochondrial 3-oxoacyl-Coenzyme A thiolase | |
| AI255831 | |
| AI265397 | |
| D18Ertd240e | |
| 0610011L04Rik | |
| acetyl-CoA acyltransferase | |
| acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | |
| 0610011L04 | |
| Acaa2 | |
| acetyl-CoA acyltransferase 2 | |
| acetyl-Coenzyme A acyltransferase II | |
| LOC113150 | |
| LOC125662 | |
| LOC147548 | |
| mitochondrial 3-ketoacyl-CoA thiolase | |
| Mitochondrial 3-oxoacyl- CoA thiolase | |
| mitochondrial acetyl-Coenzyme A acyltransferase | |
| RIKEN cDNA 0610011L04 gene |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604770 |
|---|
| Mouse chromosome position | 18 45.0 cM |
|---|
| GO ID | 0003988 |
|---|---|
| 0008415 | |
| 0016740 | |
| 0006695 | |
| 0006631 | |
| 0006629 | |
| 0008152 | |
| 0005743 | |
| 0005739 | |
| 0003824 | |
| 0016747 | |
| 0006084 | |
| 0006635 | |
| 0005759 |
| Rat chromosome position | 18q12.3 |
|---|
| Swiss-Prot Accession | B3KNP8 |
|---|---|
| P42765 | |
| Q3TIT9 | |
| Q8BWT1 | |
| Q3UKH3 | |
| P13437 | |
| Q9BUT6 | |
| Q8JZR8 |
| PIR ID | A29452 |
|---|---|
| S43440 |
| Unigene ID | Hs.200136 |
|---|---|
| Mm.245724 | |
| Rn.3786 |
| KEGG ID | hsa:10449 |
|---|---|
| mmu:52538 | |
| rno:170465 |
| EC Number | 2.3.1.16 |
|---|
| Swiss-Prot ID | THIM_RAT |
|---|---|
| THIM_HUMAN | |
| THIM_MOUSE | |
| B3KNP8_HUMAN | |
| Q3TIT9_MOUSE |
| Cell Localization | Mitochondrion |
|---|---|
| Cytoplasm | |
| Mitochondria |
| IPI ID | IPI00201413 |
|---|---|
| IPI00001539 | |
| IPI00226430 | |
| IPI00653158 | |
| IPI00873829 | |
| IPI00647480 | |
| IPI00644842 |
| Homologene ID | 4456 |
|---|
| RGD ID | 620482 |
|---|
| MGI ID | 1098623 |
|---|