| URN | urn:agi-llid:1892 |
|---|---|
| Connectivity | 3 |
| Name | Echs1 |
| Description | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
| Notes | The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. |
| Pathway | fatty acid beta degradation pathway |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| lyase activity | |
| enoyl-CoA hydratase activity |
| GO Cellular Component | soluble fraction |
|---|---|
| mitochondrion | |
| mitochondrial matrix |
| GO Biological Process | metabolic process |
|---|---|
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| lipid metabolic process |
| Ariadne Ontology | Fatty acid oxidation |
|---|
| Group | Fatty acid oxidation |
|---|---|
| catalytic activity | |
| metabolic process | |
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| lipid metabolic process | |
| lyase activity | |
| enoyl-CoA hydratase activity | |
| soluble fraction | |
| mitochondrion | |
| mitochondrial matrix |
| MedScan ID | 1892 |
|---|
| Hugo ID | 3151 |
|---|
| Human chromosome position | 10q26.2-q26.3 |
|---|
| LocusLink ID | 1892 |
|---|---|
| 93747 | |
| 140547 |
| Alias | SCEH |
|---|---|
| enoyl-CoA hydratase, mitochondrial | |
| enoyl-CoA hydratase 1 | |
| short-chain enoyl-CoA hydratase | |
| enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | |
| C80529 | |
| OTTMUSP00000033957 | |
| short chain enoyl-CoA hydratase | |
| enoyl Coenzyme A hydratase, short chain 1 | |
| Enoyl-CoA hydratase short chain 1 mitochondrial | |
| Enoyl-CoA hydratase, short chain 1, mitochondrial | |
| mitochondrial short-chain enoyl-coenzyme A hydratase 1 | |
| Echs I | |
| Echs1 | |
| enoyl Coenzyme A hydratase, short chain | |
| enoyl Coenzyme A hydratase, short chain I | |
| Enoyl-CoA hydratase I | |
| mitochondrial enoyl Coenzyme A hydratase, short chain, 1 | |
| mitochondrial enoyl Coenzyme A hydratase, short chain, I | |
| mitochondrial Enoyl-CoA hydratase | |
| mitochondrial Enoyl-CoA hydratase, short chain 1 | |
| mitochondrial Enoyl-CoA hydratase, short chain I | |
| OTTHUMP00000020811 | |
| Enoyl-CoA hydratase, mitochondrial precursor | |
| mitochondrial Enoyl-CoA hydratase precursor | |
| mitochondrial short-chain enoyl-coenzyme A hydratase 1 precursor | |
| Short chain enoyl-CoA hydratase |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602292 |
|---|
| Mouse chromosome position | 7 |
|---|---|
| 7 F4 |
| GO ID | 0004300 |
|---|---|
| 0016829 | |
| 0006635 | |
| 0006631 | |
| 0006629 | |
| 0008152 | |
| 0005759 | |
| 0005739 | |
| 0003824 | |
| 0005625 | |
| 0005515 | |
| 0006091 | |
| 0016508 |
| Rat chromosome position | 1q41 |
|---|
| Swiss-Prot Accession | P30084 |
|---|---|
| Q8BH95 | |
| Q8BU95 | |
| P14604 | |
| Q3TJK2 | |
| Q6GQS2 | |
| Q6PEN1 | |
| Q99LX7 | |
| O00739 | |
| Q5VWY1 | |
| Q96H54 |
| PIR ID | S06477 |
|---|
| Unigene ID | Hs.76394 |
|---|---|
| Mm.24452 | |
| Rn.6847 |
| KEGG ID | hsa:1892 |
|---|---|
| mmu:93747 | |
| rno:140547 |
| EC Number | 4.2.1.17 |
|---|
| Swiss-Prot ID | ECHM_RAT |
|---|---|
| ECHM_MOUSE | |
| ECHM_HUMAN |
| Cell Localization | Mitochondrion matrix |
|---|---|
| Mitochondria |
| IPI ID | IPI00207217 |
|---|---|
| IPI00454049 | |
| IPI00024993 | |
| IPI00459020 | |
| IPI00886151 |
| Homologene ID | 3018 |
|---|
| RGD ID | 69330 |
|---|
| MGI ID | 2136460 |
|---|