| URN | urn:agi-llid:1376 |
|---|---|
| Connectivity | 30 |
| Name | Cpt2 |
| Description | carnitine palmitoyltransferase II |
| Notes | The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. |
| Pathway | fatty acid beta degradation pathway |
|---|
| GO Molecular Function | transferase activity |
|---|---|
| acyltransferase activity | |
| carnitine O-palmitoyltransferase activity |
| GO Cellular Component | membrane |
|---|---|
| mitochondrion | |
| mitochondrial inner membrane |
| GO Biological Process | transport |
|---|---|
| regulation of fatty acid oxidation | |
| carnitine shuttle | |
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| lipid metabolic process | |
| long-chain fatty acid transport |
| Ariadne Ontology | Fatty acid oxidation |
|---|
| Group | Fatty acid oxidation |
|---|---|
| transport | |
| regulation of fatty acid oxidation | |
| carnitine shuttle | |
| fatty acid metabolic process | |
| fatty acid beta-oxidation | |
| lipid metabolic process | |
| long-chain fatty acid transport | |
| transferase activity | |
| acyltransferase activity | |
| carnitine O-palmitoyltransferase activity | |
| membrane | |
| mitochondrion | |
| mitochondrial inner membrane |
| MedScan ID | 1376 |
|---|
| Hugo ID | 2330 |
|---|
| Human chromosome position | 1p32 |
|---|
| LocusLink ID | 1376 |
|---|---|
| 12896 | |
| 25413 |
| Alias | CPT1 |
|---|---|
| CPTASE | |
| carnitine O-palmitoyltransferase 2, mitochondrial | |
| CPT II | |
| carnitine palmitoyltransferase II | |
| CPTII | |
| AI323697 | |
| RP23-40G2.4 | |
| OTTMUSP00000009669 | |
| OTTMUSP00000009692 | |
| Cpt-2 | |
| Carnitine O-palmitoyltransferase 2 | |
| Carnitine O-palmitoyltransferase II | |
| Carnitine O-palmitoyltransferase II, mitochondrial | |
| carnitine palmitoyltransferase 2 | |
| CPT2 | |
| mitochondrial Carnitine O-palmitoyltransferase II | |
| OTTHUMP00000010493 | |
| carnitine O-palmitoyltransferase | |
| Carnitine O-palmitoyltransferase II, mitochondrial precursor | |
| mitochondrial Carnitine O-palmitoyltransferase II precursor |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600650 |
|---|---|
| 600649 | |
| 608836 | |
| 255110 |
| Mouse chromosome position | 4 54.4 cM |
|---|
| GO ID | 0008415 |
|---|---|
| 0004095 | |
| 0016740 | |
| 0006853 | |
| 0006635 | |
| 0006631 | |
| 0006629 | |
| 0046320 | |
| 0006810 | |
| 0016020 | |
| 0005743 | |
| 0005739 | |
| 0015909 |
| Rat chromosome position | 5q35 |
|---|
| Swiss-Prot Accession | P23786 |
|---|---|
| Q53G79 | |
| Q3TFS0 | |
| Q3UN55 | |
| P52825 | |
| Q3UDA8 | |
| Q9CU20 | |
| P18886 | |
| P97781 | |
| B2R6S0 | |
| Q5SW68 | |
| Q9BQ26 |
| PIR ID | A35447 |
|---|---|
| A39018 |
| Unigene ID | Hs.713535 |
|---|---|
| Mm.307620 | |
| Rn.11389 | |
| Hs.705379 |
| KEGG ID | hsa:1376 |
|---|---|
| mmu:12896 | |
| rno:25413 |
| EC Number | 2.3.1.21 |
|---|
| Swiss-Prot ID | CPT2_RAT |
|---|---|
| CPT2_HUMAN | |
| Q3TFS0_MOUSE | |
| Q3UN55_MOUSE | |
| B2R6S0_HUMAN |
| Cell Localization | Mitochondrion inner membrane |
|---|---|
| Mitochondria |
| IPI ID | IPI00195593 |
|---|---|
| IPI00012912 | |
| IPI00881401 | |
| IPI00131424 | |
| IPI00648887 | |
| IPI00649159 | |
| IPI00649655 |
| Homologene ID | 77 |
|---|
| RGD ID | 2398 |
|---|
| MGI ID | 109176 |
|---|