| URN | urn:agi-llid:83569 |
|---|---|
| Connectivity | 0 |
| Name | Abcb11 |
| Description | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
| Notes | acts as an ATP-dependent bile salt export pump; transports taurochenodeoxycholate, taurocholate, and other bile salts [RGD] |
| Pathway | statin pharmacokinetics pathway |
|---|
| GO Molecular Function | nucleotide binding |
|---|---|
| ATP binding | |
| ATPase activity, coupled to transmembrane movement of substances | |
| ATPase activity | |
| drug transmembrane transporter activity | |
| canalicular bile acid transmembrane transporter activity |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane | |
| Golgi apparatus | |
| Golgi membrane | |
| apical plasma membrane | |
| integral to membrane |
| GO Biological Process | transmembrane transport |
|---|---|
| response to drug | |
| response to oxidative stress | |
| response to estrogen stimulus | |
| drug export | |
| canalicular bile acid transport |
| Group | transmembrane transport |
|---|---|
| response to drug | |
| response to oxidative stress | |
| response to estrogen stimulus | |
| drug export | |
| canalicular bile acid transport | |
| nucleotide binding | |
| ATP binding | |
| ATPase activity, coupled to transmembrane movement of substances | |
| ATPase activity | |
| drug transmembrane transporter activity | |
| canalicular bile acid transmembrane transporter activity | |
| membrane | |
| plasma membrane | |
| Golgi apparatus | |
| Golgi membrane | |
| apical plasma membrane | |
| integral to membrane |
| MedScan ID | 83569 |
|---|
| LocusLink ID | 83569 |
|---|
| Alias | Bsep |
|---|---|
| Spgp | |
| bile salt export pump | |
| sister of P-glycoprotein | |
| ATP-binding cassette sub-family B member 11 | |
| ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
| Organism | Rattus norvegicus |
|---|
| GenBank ID | NW_001084813 |
|---|---|
| NM_031760 | |
| NP_113948 | |
| AC_000071 | |
| AF372505 | |
| AAN63501 | |
| AF010597 | |
| AAC24753 | |
| U69487 | |
| AAC40084 | |
| O70127 | |
| O88331 | |
| NW_047672 | |
| XM_579531 | |
| XP_579531 |
| GO ID | 0005524 |
|---|---|
| 0016887 | |
| 0042626 | |
| 0015126 | |
| 0015238 | |
| 0000166 | |
| 0015722 | |
| 0046618 | |
| 0042493 | |
| 0043627 | |
| 0006979 | |
| 0055085 | |
| 0005794 | |
| 0000139 | |
| 0016324 | |
| 0016021 | |
| 0016020 | |
| 0005886 | |
| 0005515 | |
| 0006810 | |
| 0045177 | |
| 0046581 | |
| 0005624 |
| Swiss-Prot Accession | O70127 |
|---|---|
| O88331 |
| PIR ID | T42842 |
|---|
| Unigene ID | Rn.14539 |
|---|
| KEGG ID | rno:83569 |
|---|
| Swiss-Prot ID | ABCBB_RAT |
|---|
| Cell Localization | Membrane |
|---|
| IPI ID | IPI00195615 |
|---|---|
| IPI00559175 |
| RGD ID | 619930 |
|---|