| Name | Aqp2 |
|---|---|
| Description | aquaporin 2 (collecting duct) |
| Notes | This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus. |
| Owner | Public |
| URN | urn:agi-llid:359 |
| Connectivity | 344 |
| LocusLink ID | 359 |
|---|---|
| 11827 | |
| 25386 |
| OMIM ID | 107777 |
|---|---|
| 125800 |
| GO ID | 0003779 |
|---|---|
| 0005215 | |
| 0015250 | |
| 0007588 | |
| 0009651 | |
| 0006810 | |
| 0006833 | |
| 0016324 | |
| 0031410 | |
| 0030659 | |
| 0016021 | |
| 0005624 | |
| 0005886 | |
| 0043234 | |
| 0005615 | |
| 0005887 | |
| 0016020 | |
| 0030104 |
| Hugo ID | 634 |
|---|
| Human chromosome position | 12q12-q13 |
|---|
| Unigene ID | Hs.130730 |
|---|---|
| Mm.20206 | |
| Rn.90076 |
| KEGG ID | hsa:359 |
|---|---|
| mmu:11827 | |
| rno:25386 |
| Alias | AQP-CD |
|---|---|
| WCH-CD | |
| MGC34501 | |
| aquaporin 2 | |
| aquaporin-CD | |
| collecting duct water channel protein | |
| cph | |
| jpk | |
| ADH water channel | |
| water channel protein for renal collecting duct | |
| AQP-2 | |
| MGC156502 | |
| aquaporin-2 | |
| aquaporin 2 (collecting duct) | |
| Collecting duct water channel protein | |
| aquaporin II | |
| ADH water channels | |
| AQP2 | |
| Water channel protein for renal collecting duct |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Mouse chromosome position | 15 F1 |
|---|
| Rat chromosome position | 7q36 |
|---|
| Cell Localization | Plasma membrane |
|---|
| Homologene ID | 20137 |
|---|
| Pathway | vasopressin signaling pathway via receptor type 2 |
|---|---|
| vasopressin signaling pathway - first |
| MGI ID | 1096865 |
|---|---|
| 88481 |
| Ariadne Ontology | Water transport |
|---|
| RGD ID | 2142 |
|---|
| GO Molecular Function | transporter activity |
|---|---|
| actin binding | |
| water channel activity |
| GO Cellular Component | membrane |
|---|---|
| apical plasma membrane | |
| membrane fraction | |
| cytoplasmic vesicle | |
| cytoplasmic vesicle membrane | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane | |
| extracellular space | |
| protein complex |
| GO Biological Process | water homeostasis |
|---|---|
| transport | |
| excretion | |
| water transport | |
| response to salt stress |
| Group | membrane |
|---|---|
| apical plasma membrane | |
| membrane fraction | |
| cytoplasmic vesicle | |
| cytoplasmic vesicle membrane | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane | |
| extracellular space | |
| protein complex | |
| transporter activity | |
| actin binding | |
| water channel activity | |
| water homeostasis | |
| transport | |
| excretion | |
| water transport | |
| response to salt stress | |
| Water transport |