| Name | Akap7 |
|---|---|
| Description | A kinase (PRKA) anchor protein 7 |
| Notes | This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined. |
| Owner | Public |
| URN | urn:agi-llid:9465 |
| Connectivity | 27 |
| LocusLink ID | 9465 |
|---|---|
| 432442 | |
| 361458 |
| OMIM ID | 604693 |
|---|
| GO ID | 0003824 |
|---|---|
| 0051018 | |
| 0016070 | |
| 0008150 | |
| 0007242 | |
| 0006811 | |
| 0008104 | |
| 0016324 | |
| 0005737 | |
| 0005829 | |
| 0005622 | |
| 0016328 | |
| 0005886 | |
| 0016301 | |
| 0005515 | |
| 0019901 | |
| 0007178 | |
| 0016020 | |
| 0005634 |
| Hugo ID | 377 |
|---|
| Human chromosome position | 6q23 |
|---|
| Unigene ID | Hs.486483 |
|---|---|
| Mm.179069 | |
| Mm.448245 | |
| Mm.456255 | |
| Rn.204773 |
| KEGG ID | hsa:9465 |
|---|---|
| mmu:432442 | |
| rno:361458 |
| Alias | AKAP18 |
|---|---|
| A-kinase anchor protein 7 | |
| OTTHUMP00000040266 | |
| A-kinase anchor protein 9 kDa | |
| A-kinase anchoring protein 18 | |
| A-kinase anchor protein, 18-kD | |
| protein kinase A anchoring protein 7 | |
| A-kinase anchor protein 7, isoform alpha | |
| AKAP15 | |
| AI662165 | |
| BB170514 | |
| 6430401D08 | |
| Akap7 | |
| AKAP18d | |
| MGC112559 | |
| A-kinase anchoring protein 18 ,isoform delta | |
| A kinase (PRKA) anchor protein 7 | |
| A-kinase anchor protein 18 | |
| A-kinase anchoring protein 18 beta | |
| A-kinase anchoring protein 18 gamma | |
| A-kinase anchoring protein 7 | |
| A-kinase anchoring protein 7 isoform beta | |
| A-kinase anchoring protein 7 isoform gamma | |
| PRKA anchor protein 7 | |
| A-kinase anchoring 18 | |
| hypothetical protein 6430401D08 | |
| expressed sequence BB170514 | |
| expressed sequence AI662165 | |
| A kinase (PRKA) anchor protein VII | |
| PRKA anchor protein VII | |
| A-kinase anchoring protein VII | |
| A-kinase anchor protein VII | |
| A-kinase anchoring protein 7 isoform alpha | |
| AKAP18s | |
| AKAP15s | |
| protein kinase A anchoring protein VII |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Mouse chromosome position | 10 A4 |
|---|
| Rat chromosome position | 1p12 |
|---|
| Homologene ID | 49463 |
|---|
| Pathway | vasopressin signaling pathway via receptor type 2 |
|---|---|
| vasopressin signaling pathway - first |
| MGI ID | 1859150 |
|---|
| RGD ID | 1303071 |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| protein binding | |
| protein kinase A binding | |
| protein kinase binding | |
| kinase activity |
| GO Cellular Component | membrane |
|---|---|
| intracellular | |
| apical plasma membrane | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| plasma membrane | |
| lateral plasma membrane |
| GO Biological Process | biological_process |
|---|---|
| intracellular signaling cascade | |
| transmembrane receptor protein serine-threonine kinase signaling pathway | |
| RNA metabolic process | |
| ion transport | |
| protein localization |
| Group | membrane |
|---|---|
| intracellular | |
| apical plasma membrane | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| plasma membrane | |
| lateral plasma membrane | |
| catalytic activity | |
| protein binding | |
| protein kinase A binding | |
| protein kinase binding | |
| kinase activity | |
| biological_process | |
| intracellular signaling cascade | |
| transmembrane receptor protein serine-threonine kinase signaling pathway | |
| RNA metabolic process | |
| ion transport | |
| protein localization |