| URN | urn:agi-llid:8837 |
|---|---|
| Connectivity | 217 |
| Name | Cflar |
| Description | CASP8 and FADD-like apoptosis regulator |
| Notes | an anti-apoptosis protein [RGD] |
| Pathway | Apoptosis |
|---|---|
| Trail mediated signaling pathway | |
| FasL mediated signaling pathway |
| GO Molecular Function | cysteine-type endopeptidase activity |
|---|
| GO Cellular Component | cytoplasm |
|---|
| GO Biological Process | interspecies interaction between organisms |
|---|---|
| positive regulation of I-kappaB kinase-NF-kappaB cascade | |
| induction of apoptosis by extracellular signals | |
| negative regulation of apoptosis | |
| anti-apoptosis | |
| regulation of apoptosis | |
| negative regulation of caspase activity | |
| apoptosis | |
| proteolysis |
| Ariadne Ontology | FLIP |
|---|
| Group | FLIP |
|---|---|
| interspecies interaction between organisms | |
| positive regulation of I-kappaB kinase-NF-kappaB cascade | |
| induction of apoptosis by extracellular signals | |
| negative regulation of apoptosis | |
| anti-apoptosis | |
| regulation of apoptosis | |
| negative regulation of caspase activity | |
| apoptosis | |
| proteolysis | |
| cysteine-type endopeptidase activity | |
| cytoplasm |
| MedScan ID | 8837 |
|---|
| Hugo ID | 1876 |
|---|
| Human chromosome position | 2q33-q34 |
|---|
| LocusLink ID | 8837 |
|---|---|
| 12633 | |
| 117279 |
| Alias | CASH |
|---|---|
| FLIP | |
| MRIT | |
| CLARP | |
| FLAME | |
| Casper | |
| FLAME1 | |
| c-FLIP | |
| FLAME-1 | |
| I-FLICE | |
| c-FLIPL | |
| c-FLIPR | |
| c-FLIPS | |
| CASP8AP1 | |
| CASP8 and FADD-like apoptosis regulator | |
| usurpin beta | |
| caspase homolog | |
| OTTHUMP00000206475 | |
| OTTHUMP00000206482 | |
| OTTHUMP00000207360 | |
| inhibitor of FLICE | |
| caspase-eight-related protein | |
| MACH-related inducer of toxicity | |
| FADD-like anti-apoptotic molecule | |
| FADD-like antiapoptotic molecule 1 | |
| caspase-related inducer of apoptosis | |
| cellular FLICE-like inhibitory protein | |
| caspase-like apoptosis regulatory protein | |
| Gm9845 | |
| AI646576 | |
| AU021929 | |
| MGC103395 | |
| 2310024N18Rik | |
| A430105C05Rik | |
| ENSMUSG00000072980 | |
| usurpin | |
| OTTMUSP00000021141 | |
| OTTMUSP00000021142 | |
| OTTMUSP00000021143 | |
| OTTMUSP00000021144 | |
| MGC108616 | |
| 2310024N18 | |
| A430105C05 | |
| CASP8AP I | |
| Caspase-8-related protein | |
| CFLAR | |
| FADD-like antiapoptotic molecule I | |
| Flame I | |
| FLICE inhibitory protein long splice form | |
| FLICE inhibitory protein short splice form | |
| I-FLICEs | |
| Usurpins | |
| Cellular FLICE-like inhibitory protein | |
| MACH- related inducer of toxicity | |
| RIKEN cDNA 2310024N18 gene | |
| RIKEN cDNA A430105C05 gene | |
| Flame-1s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 603599 |
|---|
| Mouse chromosome position | 1 30.1 cM |
|---|
| GO ID | 0004197 |
|---|---|
| 0006916 | |
| 0008624 | |
| 0044419 | |
| 0043123 | |
| 0006508 | |
| 0042981 | |
| 0006915 | |
| 0043066 | |
| 0043154 | |
| 0005737 | |
| 0005515 | |
| 0008234 |
| Rat chromosome position | 9q31 |
|---|
| Swiss-Prot Accession | O15519 |
|---|---|
| Q53TS6 | |
| Q59F61 | |
| Q5U4G3 | |
| O35732 | |
| Q812G4 | |
| Q3TTS9 | |
| C0H5Y5 | |
| Q99MZ5 | |
| O35707 | |
| O35733 | |
| B7Z9F9 | |
| O14673 | |
| O14674 | |
| O14675 | |
| O15137 | |
| O15138 | |
| O15356 | |
| O15510 | |
| O43618 | |
| O43619 | |
| O43620 | |
| O60458 | |
| O60459 | |
| Q54AF1 | |
| Q96TE4 | |
| Q9UEW1 |
| Unigene ID | Hs.390736 |
|---|---|
| Mm.336848 | |
| Rn.204752 |
| KEGG ID | hsa:8837 |
|---|---|
| mmu:12633 | |
| rno:117279 |
| Swiss-Prot ID | CFLAR_MOUSE |
|---|---|
| CFLAR_HUMAN | |
| Q53TS6_HUMAN | |
| Q812G4_MOUSE | |
| C0H5Y5_RAT | |
| Q99MZ5_RAT | |
| Q5U4G3_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00133915 |
|---|---|
| IPI00230112 | |
| IPI00007287 | |
| IPI00216956 | |
| IPI00216957 | |
| IPI00216958 | |
| IPI00216959 | |
| IPI00216960 | |
| IPI00216962 | |
| IPI00216963 | |
| IPI00219239 | |
| IPI00219241 | |
| IPI00219242 | |
| IPI00219243 | |
| IPI00394836 | |
| IPI00414806 | |
| IPI00330059 | |
| IPI00198564 | |
| IPI00654442 | |
| IPI00556163 | |
| IPI00652614 | |
| IPI00830184 | |
| IPI00410793 |
| Homologene ID | 7652 |
|---|
| RGD ID | 620847 |
|---|
| MGI ID | 1336166 |
|---|