| URN | urn:agi-llid:5864 |
|---|---|
| Total Entities | 0 |
| Connectivity | 229 |
| Name | Rab3a |
| Description | Rab3A, member RAS oncogene family |
| Notes | regulated synaptic vesicle endocytosis [RGD] |
| Ariadne Ontology | Vesicular secretory pathway |
|---|---|
| Oncogenes | |
| Secreted proteins |
| GO Molecular Function | protein C-terminus binding |
|---|---|
| GTPase binding | |
| ATPase binding | |
| nucleotide binding | |
| GTP binding | |
| GTPase activity | |
| ATPase activator activity |
| GO Cellular Component | membrane |
|---|---|
| clathrin-sculpted glutamate transport vesicle membrane | |
| clathrin-sculpted monoamine transport vesicle membrane | |
| clathrin-sculpted acetylcholine transport vesicle membrane | |
| clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | |
| protein complex | |
| plasma membrane | |
| intracellular organelle | |
| cytosol | |
| acrosomal vesicle | |
| synaptic vesicle |
| GO Biological Process | synaptic transmission |
|---|---|
| neuromuscular synaptic transmission | |
| regulation of synaptic vesicle fusion to presynaptic membrane | |
| small GTPase mediated signal transduction | |
| Rab protein signal transduction | |
| positive regulation of ATPase activity | |
| regulation of exocytosis | |
| axonogenesis | |
| glutamate secretion | |
| neurotransmitter secretion | |
| maintenance of presynaptic active zone structure | |
| exocytosis | |
| synaptic vesicle exocytosis | |
| GTP catabolic process | |
| mitochondrion organization | |
| synaptic vesicle maturation | |
| response to electrical stimulus | |
| post-embryonic development | |
| lung development | |
| respiratory system process | |
| sensory perception of touch | |
| transport | |
| protein transport |
| Pathway | Exocytosis |
|---|---|
| altered insulin secretion pathway | |
| insulin secretion pathway | |
| altered insulin secretion pathway | |
| insulin secretion pathway | |
| altered insulin secretion pathway | |
| insulin secretion pathway | |
| altered insulin secretion pathway |
| Group | Vesicular secretory pathway |
|---|---|
| Oncogenes | |
| synaptic transmission | |
| neuromuscular synaptic transmission | |
| regulation of synaptic vesicle fusion to presynaptic membrane | |
| small GTPase mediated signal transduction | |
| Rab protein signal transduction | |
| positive regulation of ATPase activity | |
| regulation of exocytosis | |
| axonogenesis | |
| glutamate secretion | |
| neurotransmitter secretion | |
| maintenance of presynaptic active zone structure | |
| exocytosis | |
| synaptic vesicle exocytosis | |
| GTP catabolic process | |
| mitochondrion organization | |
| synaptic vesicle maturation | |
| response to electrical stimulus | |
| post-embryonic development | |
| lung development | |
| respiratory system process | |
| sensory perception of touch | |
| transport | |
| protein transport | |
| protein C-terminus binding | |
| GTPase binding | |
| ATPase binding | |
| nucleotide binding | |
| GTP binding | |
| GTPase activity | |
| ATPase activator activity | |
| membrane | |
| clathrin-sculpted glutamate transport vesicle membrane | |
| clathrin-sculpted monoamine transport vesicle membrane | |
| clathrin-sculpted acetylcholine transport vesicle membrane | |
| clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | |
| protein complex | |
| plasma membrane | |
| intracellular organelle | |
| cytosol | |
| acrosomal vesicle | |
| synaptic vesicle | |
| Secreted proteins |
| MedScan ID | 5864 |
|---|
| Hugo ID | 9777 |
|---|
| Human chromosome position | 19p13.2 |
|---|
| LocusLink ID | 5864 |
|---|---|
| 19339 | |
| 25531 |
| Alias | ras-related protein Rab-3A |
|---|---|
| RAS-associated protein RAB3A | |
| RAB3 | |
| Ras-related small GTP binding protein 3A | |
| Rab3a | |
| LOC96387 | |
| RAB3A, member RAS oncogene family | |
| OTTMUSP00000025402 | |
| OTTMUSP00000018420 | |
| OTTMUSP00000018415 | |
| OTTMUSP00000018416 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 179490 |
|---|
| Unigene ID | Hs.27744 |
|---|---|
| Mm.5083 | |
| Rn.44409 |
| KEGG ID | hsa:5864 |
|---|---|
| mmu:19339 | |
| rno:25531 |
| Swiss-Prot Accession | P20336 |
|---|---|
| P63011 | |
| Q0PD63 | |
| P63012 | |
| A8K0J4 | |
| Q9NYE1 | |
| P05713 | |
| Q3TSL4 | |
| Q05D37 |
| GO ID | 0001671 |
|---|---|
| 0051117 | |
| 0005525 | |
| 0003924 | |
| 0051020 | |
| 0008022 | |
| 0006184 | |
| 0007409 | |
| 0014047 | |
| 0030324 | |
| 0048790 | |
| 0007005 | |
| 0007274 | |
| 0007269 | |
| 0009791 | |
| 0015031 | |
| 0031630 | |
| 0003016 | |
| 0051602 | |
| 0050975 | |
| 0007264 | |
| 0007268 | |
| 0016079 | |
| 0016188 | |
| 0060201 | |
| 0061202 | |
| 0060203 | |
| 0070083 | |
| 0005886 | |
| 0043234 | |
| 0008021 | |
| 0000166 | |
| 0006887 | |
| 0032781 | |
| 0017157 | |
| 0006810 | |
| 0001669 | |
| 0005829 | |
| 0043229 | |
| 0016020 | |
| 0032482 | |
| 0005626 | |
| 0005625 | |
| 0019717 | |
| 0005515 | |
| 0005737 | |
| 0008565 | |
| 0006886 |
| PIR ID | C34323 |
|---|---|
| S01765 | |
| S34070 |
| Swiss-Prot ID | RAB3A_HUMAN |
|---|---|
| RAB3A_RAT | |
| RAB3A_MOUSE | |
| Q0PD63_MOUSE | |
| A8K0J4_HUMAN |
| Cell Localization | Cell membrane |
|---|---|
| Golgi |
| IPI ID | IPI00023504 |
|---|---|
| IPI00325762 | |
| IPI00122965 | |
| IPI00807920 | |
| IPI00885980 |
| Mouse chromosome position | 8 32.6 cM |
|---|
| Rat chromosome position | 16p14 |
|---|
| Homologene ID | 20629 |
|---|
| MGI ID | 97843 |
|---|
| RGD ID | 3528 |
|---|
| Primary Cell Localization | Golgi |
|---|