Protein Slc2a2

URN urn:agi-llid:6514
Connectivity 147
Name Slc2a2
Description solute carrier family 2 (facilitated glucose transporter), member 2
Notes Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor.

Pathway insulin secretion pathway
altered insulin secretion pathway
altered insulin secretion pathway

GO Molecular Function transporter activity
insulin receptor binding
substrate-specific transmembrane transporter activity
glucose transmembrane transporter activity
D-glucose transmembrane transporter activity
dehydroascorbic acid transporter activity

GO Cellular Component membrane
plasma membrane
brush border
cytoplasm
endosome
cytosol
membrane fraction
basolateral plasma membrane
integral to membrane
integral to plasma membrane
brush border membrane

GO Biological Process sugar utilization
transmembrane transport
transport
carbohydrate metabolic process
carbohydrate transport
dehydroascorbic acid transport
glucose transport
fructose transport

Ariadne Ontology Glucose import

Group Glucose import
transporter activity
sugar utilization
transmembrane transport
transport
carbohydrate metabolic process
carbohydrate transport
dehydroascorbic acid transport
glucose transport
fructose transport
insulin receptor binding
substrate-specific transmembrane transporter activity
glucose transmembrane transporter activity
D-glucose transmembrane transporter activity
dehydroascorbic acid transporter activity
membrane
plasma membrane
brush border
cytoplasm
endosome
cytosol
membrane fraction
basolateral plasma membrane
integral to membrane
integral to plasma membrane
brush border membrane

MedScan ID 6514

Hugo ID 11006

Human chromosome position 3q26.1-q26.2

LocusLink ID 6514
20526
25351

Alias GLUT2
solute carrier family 2, facilitated glucose transporter member 2
GLUT-2
glucose transporter type 2, liver
AI266973
liver-type glucose transporter
GTT2
facilitated glucose transporter 2
facilitated glucose transporter II
Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
solute carrier family 2 a2
Solute carrier family 2 A2 (gkucose transporter, type 2)
solute carrier family 2, member 2
solute carrier family 2, member II

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000003
NM_000340
NP_000331
NT_005612
NW_001838884
NW_921807
NG_008108
AC_000135
AC_000046
AC061708
AC092918
CH471052
EAW78498
EAW78499
EAW78500
L09674
AK290846
BAF83535
AK292741
BAF85430
AK298418
BAH12783
AK313622
BAG36383
BC060041
AAH60041
J03810
AAA59514
P11168
Q6PAU8
NC_000069
NM_031197
NP_112474
NT_162143
NW_001030719
AC_000025
AC121268
CH466530
EDL34941
EDL34942
EDL34943
X78722
CAA55368
AI120520
AK005068
BAB23792
AK149532
AK165430
BAE38184
BC034675
AAH34675
S77926
AAB20847
X15684
CAA33719
X16986
CAA34855
P14246
NC_005101
NM_012879
NP_037011
NW_047625
NW_001084800
AC_000070
CH473961
EDM01137
EDM01138
EDM01139
L28126
AAB05001
L28127
AAA99951
L28128
AAA99952
L28129
AAA99953
L28130
AAA99954
L28131
AAA99955
L28132
AAA99956
L28133
AAA99957
L28134
AAA99958
L28135
AAA99959
L28678
BC078875
AAH78875
J03145
AAA41298
P12336
Q63235
Q68FZ1
Q6LE97
Q6LE99
Q6LEA0
Q6LEA1
Q6LEA2
Q6LEA3
Q6LEA4
Q9UCW9
XM_001063900
XP_001063900

OMIM ID 138160
227810

Mouse chromosome position 3 14.4 cM

GO ID 0055056
0033300
0005355
0005158
0022891
0005215
0005975
0008643
0015755
0015758
0055085
0016323
0031526
0005737
0005829
0005768
0005887
0005624
0005886
0070837
0007587
0006810
0005903
0016021
0016020
0005351

Rat chromosome position 2q24

Swiss-Prot Accession P11168
Q6PAU8
P14246
Q68FZ1
P12336
Q63235
Q6LE97
Q6LE99
Q6LEA0
Q6LEA1
Q6LEA2
Q6LEA3
Q6LEA4
A8K481
B2R936
Q9UCW9
Q3TNA5
Q9DBA7

PIR ID A31318
S06920

Unigene ID Hs.167584
Mm.18443
Rn.89295

KEGG ID hsa:6514
mmu:20526
rno:25351

Swiss-Prot ID GTR2_HUMAN
GTR2_MOUSE
Q68FZ1_RAT

Cell Localization Membrane
Plasma membrane

IPI ID IPI00003905
IPI00311809
IPI00196643
IPI00744509
IPI00882453
IPI00882410

Homologene ID 68047

RGD ID 3705

MGI ID 1095438