| URN | urn:agi-llid:5230 |
|---|---|
| Connectivity | 59 |
| Name | Pgk1 |
| Description | phosphoglycerate kinase 1 |
| Notes | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. A pseudogene of this gene has been found on the X-chromosome and another on chromosome 19. |
| Pathway | New Pathway |
|---|---|
| glycolysis/gluconeogenesis pathway | |
| gluconeogenesis pathway | |
| glycolysis pathway |
| GO Molecular Function | nucleotide binding |
|---|---|
| transferase activity | |
| ADP binding | |
| ATP binding | |
| kinase activity | |
| phosphoglycerate kinase activity |
| GO Cellular Component | soluble fraction |
|---|---|
| cytoplasm | |
| cytosol |
| GO Biological Process | glycolysis |
|---|---|
| gluconeogenesis | |
| phosphorylation | |
| carbohydrate metabolic process |
| Ariadne Ontology | Glucose metabolism |
|---|
| Group | Glucose metabolism |
|---|---|
| glycolysis | |
| gluconeogenesis | |
| phosphorylation | |
| carbohydrate metabolic process | |
| nucleotide binding | |
| transferase activity | |
| ADP binding | |
| ATP binding | |
| kinase activity | |
| phosphoglycerate kinase activity | |
| soluble fraction | |
| cytoplasm | |
| cytosol |
| MedScan ID | 5230 |
|---|
| Hugo ID | 8896 |
|---|
| Human chromosome position | Xq13 |
|---|
| LocusLink ID | 5230 |
|---|---|
| 18655 | |
| 24644 | |
| 433594 | |
| 668435 |
| Alias | PGKA |
|---|---|
| MIG10 | |
| MGC8947 | |
| MGC117307 | |
| MGC142128 | |
| RP4-570L12.1 | |
| phosphoglycerate kinase 1 | |
| PRP 2 | |
| primer recognition protein 2 | |
| cell migration-inducing gene 10 protein | |
| Pgk-1 | |
| MGC118097 | |
| OTTMUSP00000019855 | |
| Pgk | |
| MGC105265 | |
| LOC214853 | |
| migration-inducing gene 10 protein | |
| OTTHUMP00000023595 | |
| PGK I | |
| PGK1 | |
| phosphoglycerate kinase (EC 2.7.2.3) | |
| phosphoglycerate kinase (Echymipera rufescens) | |
| phosphoglycerate kinase I | |
| Primer recognition protein II | |
| PRP II |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 311800 |
|---|---|
| 300653 |
| Mouse chromosome position | X 45.0 cM |
|---|---|
| 3 | |
| 12 |
| GO ID | 0005524 |
|---|---|
| 0000166 | |
| 0004618 | |
| 0016740 | |
| 0006096 | |
| 0016310 | |
| 0005737 | |
| 0043531 | |
| 0016301 | |
| 0005975 | |
| 0006094 | |
| 0005829 | |
| 0005625 |
| Rat chromosome position | Xq31 |
|---|
| Swiss-Prot Accession | A8K4W6 |
|---|---|
| P00558 | |
| P09411 | |
| P16617 | |
| Q3TPE6 | |
| Q3UKV8 | |
| Q5XJE7 | |
| Q5M945 | |
| Q6P508 | |
| Q5J7W1 | |
| Q6IBT6 | |
| Q8NI87 |
| PIR ID | A25567 |
|---|---|
| A33792 | |
| I59050 |
| Unigene ID | Hs.78771 |
|---|---|
| Mm.336204 | |
| Mm.336205 | |
| Rn.108127 | |
| Hs.701989 |
| KEGG ID | hsa:5230 |
|---|---|
| mmu:18655 | |
| rno:24644 | |
| mmu:433594 | |
| mmu:668435 |
| EC Number | 2.7.2.3 |
|---|
| Swiss-Prot ID | PGK1_MOUSE |
|---|---|
| PGK1_RAT | |
| PGK1_HUMAN | |
| A8K4W6_HUMAN |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00555069 |
|---|---|
| IPI00231426 | |
| IPI00169383 |
| Homologene ID | 21542 |
|---|
| RGD ID | 619878 |
|---|
| MGI ID | 97555 |
|---|---|
| 3643179 | |
| 3648557 |