| URN | urn:agi-llid:4644 |
|---|---|
| Total Entities | 0 |
| Connectivity | 381 |
| Name | Myo5a |
| Description | myosin VA (heavy chain 12, myoxin) |
| Notes | may play a role in secretory granule transport [RGD] |
| GO Molecular Function | motor activity |
|---|---|
| microfilament motor activity | |
| calcium-dependent protein binding | |
| ATP-dependent protein binding | |
| calmodulin binding | |
| SNARE binding | |
| syntaxin-1 binding | |
| Rab GTPase binding | |
| actin binding | |
| protein heterodimerization activity | |
| nucleotide binding | |
| ATP binding | |
| calcium ion binding |
| GO Cellular Component | cell |
|---|---|
| myosin complex | |
| intermediate filament | |
| actomyosin | |
| microtubule plus-end | |
| actomyosin, myosin complex part | |
| cytoplasm | |
| Golgi apparatus | |
| secretory granule | |
| insulin-responsive compartment | |
| synaptic vesicle | |
| melanosome | |
| growth cone | |
| ruffle | |
| neuron projection | |
| photoreceptor outer segment | |
| axon | |
| neuronal cell body |
| GO Biological Process | pigmentation |
|---|---|
| long-chain fatty acid biosynthetic process | |
| melanin biosynthetic process | |
| melanin metabolic process | |
| neuromuscular process controlling balance | |
| visual perception | |
| myelination | |
| odontogenesis | |
| anagen | |
| developmental pigmentation | |
| melanocyte differentiation | |
| synapse organization | |
| regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | |
| synaptic transmission | |
| insulin secretion | |
| exocytosis | |
| regulation of exocytosis | |
| actin filament-based movement | |
| vesicle transport along actin filament | |
| melanosome localization | |
| melanosome transport | |
| protein localization to plasma membrane | |
| cellular response to insulin stimulus | |
| locomotion involved in locomotory behavior | |
| cellular protein metabolic process | |
| transport | |
| vesicle-mediated transport | |
| protein transport | |
| endoplasmic reticulum localization | |
| secretory granule localization |
| Pathway | Melanoma Overview |
|---|---|
| insulin responsive facilitative sugar transporter mediated glucose transport pathway | |
| altered insulin responsive facilitative sugar transporter mediated glucose transport pathway | |
| insulin responsive facilitative sugar transporter mediated glucose transport pathway |
| Group | Actomyosin based movement |
|---|---|
| pigmentation | |
| long-chain fatty acid biosynthetic process | |
| melanin biosynthetic process | |
| melanin metabolic process | |
| neuromuscular process controlling balance | |
| visual perception | |
| myelination | |
| odontogenesis | |
| anagen | |
| developmental pigmentation | |
| melanocyte differentiation | |
| synapse organization | |
| regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | |
| synaptic transmission | |
| insulin secretion | |
| exocytosis | |
| regulation of exocytosis | |
| actin filament-based movement | |
| vesicle transport along actin filament | |
| melanosome localization | |
| melanosome transport | |
| protein localization to plasma membrane | |
| cellular response to insulin stimulus | |
| locomotion involved in locomotory behavior | |
| motor activity | |
| microfilament motor activity | |
| cellular protein metabolic process | |
| transport | |
| vesicle-mediated transport | |
| protein transport | |
| endoplasmic reticulum localization | |
| secretory granule localization | |
| calcium-dependent protein binding | |
| ATP-dependent protein binding | |
| calmodulin binding | |
| SNARE binding | |
| syntaxin-1 binding | |
| Rab GTPase binding | |
| actin binding | |
| protein heterodimerization activity | |
| nucleotide binding | |
| ATP binding | |
| calcium ion binding | |
| cell | |
| myosin complex | |
| intermediate filament | |
| actomyosin | |
| microtubule plus-end | |
| actomyosin, myosin complex part | |
| cytoplasm | |
| Golgi apparatus | |
| secretory granule | |
| insulin-responsive compartment | |
| synaptic vesicle | |
| melanosome | |
| growth cone | |
| ruffle | |
| neuron projection | |
| photoreceptor outer segment | |
| axon | |
| neuronal cell body | |
| Secreted proteins |
| LocusLink ID | 4644 |
|---|---|
| 17918 | |
| 25017 |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0005524 |
|---|---|
| 0017137 | |
| 0003779 | |
| 0005509 | |
| 0005516 | |
| 0000146 | |
| 0030048 | |
| 0042640 | |
| 0044267 | |
| 0032869 | |
| 0051643 | |
| 0006887 | |
| 0030073 | |
| 0031987 | |
| 0042759 | |
| 0042438 | |
| 0030318 | |
| 0032402 | |
| 0042552 | |
| 0042476 | |
| 0072659 | |
| 0015031 | |
| 0031585 | |
| 0032252 | |
| 0050808 | |
| 0007268 | |
| 0006810 | |
| 0016192 | |
| 0007601 | |
| 0005794 | |
| 0042641 | |
| 0005737 | |
| 0030426 | |
| 0032593 | |
| 0005882 | |
| 0042470 | |
| 0035371 | |
| 0016459 | |
| 0043005 | |
| 0043025 | |
| 0001750 | |
| 0001726 | |
| 0043008 | |
| 0000149 | |
| 0048306 | |
| 0003774 | |
| 0000166 | |
| 0046982 | |
| 0017075 | |
| 0048066 | |
| 0006582 | |
| 0032400 | |
| 0050885 | |
| 0043473 | |
| 0017157 | |
| 0030050 | |
| 0042642 | |
| 0030424 | |
| 0005623 | |
| 0030141 | |
| 0008021 | |
| 0051015 | |
| 0003674 | |
| 0008150 | |
| 0051010 | |
| 0005515 | |
| 0007010 |
| Alias | GS1 |
|---|---|
| MYO5 | |
| MYH12 | |
| MYR12 | |
| unconventional myosin-Va | |
| myoxin | |
| myosin V | |
| myosin-12 | |
| myosin-Va | |
| myosin, heavy polypeptide kinase | |
| dilute myosin heavy chain, non-muscle | |
| d | |
| Dbv | |
| MVa | |
| flr | |
| MyoVA | |
| Sev-1 | |
| flail | |
| d-120J | |
| AI413174 | |
| AI661011 | |
| 9630007J19Rik | |
| RP24-189I2.1 | |
| flailer | |
| dilute lethal-20J protein | |
| Dop | |
| myosin 5a | |
| dilute-opisthotonus | |
| Dilute | |
| Sev I | |
| mysoin heavy chain XII | |
| Myosin Va | |
| myosin VA (heavy chain 12, myoxin) | |
| mysoin heavy chain 12 | |
| OTTHUMP00000174452 | |
| OTTHUMP00000174453 | |
| OTTMUSP00000017756 | |
| OTTMUSP00000019176 | |
| Myosin heavy chain 12 | |
| RIKEN cDNA 9630007J19 gene | |
| OTTMUSP00000046608 | |
| 9630007J19 | |
| actin-associated molecular motor | |
| Myo5a | |
| d-120Js | |
| dilute lethal-20J (d-l20J) protein | |
| lethal-20J | |
| LOC113119 | |
| LOC116110 | |
| mus musculus dilute, myosin heavy chain 12, gallus gallus p190 | |
| hypothetical protein LOC269036 | |
| myosin VA (heavy polypeptide 12, myoxin) | |
| Myosin heavy chain 12 | |
| LOC269036 |
| Mouse chromosome position | 9 42.26 cM |
|---|---|
| 9 42.0 cM |
| OMIM ID | 160777 |
|---|---|
| 214450 |
| Rat chromosome position | 8q24 |
|---|
| Hugo ID | 7602 |
|---|
| Human chromosome position | 15q21 |
|---|
| Swiss-Prot Accession | Q9UES4 |
|---|---|
| Q9Y4I1 | |
| A8CDT9 | |
| F8WE88 | |
| G3V394 | |
| Q99104 | |
| Q9QYF3 | |
| A8MZC5 | |
| O60653 | |
| Q07902 | |
| Q16249 | |
| Q9UE30 | |
| Q9UE31 | |
| E9PUE5 |
| PIR ID | A53016 |
|---|---|
| A59254 | |
| B59254 | |
| I52966 | |
| A46761 |
| Unigene ID | Hs.21213 |
|---|---|
| Hs.596221 | |
| Mm.3645 | |
| Rn.44865 |
| KEGG ID | hsa:4644 |
|---|---|
| mmu:17918 | |
| rno:25017 |
| Swiss-Prot ID | MYO5A_RAT |
|---|---|
| MYO5A_HUMAN | |
| MYO5A_MOUSE |
| Ensembl ID | ENSG00000197535 |
|---|---|
| ENSP00000382177 | |
| ENST00000399231 | |
| ENSP00000348693 | |
| ENST00000356338 | |
| ENSP00000382179 | |
| ENST00000399233 | |
| ENSP00000350945 | |
| ENST00000358212 | |
| ENSMUSG00000034593 | |
| ENSMUSP00000116028 | |
| ENSMUST00000123128 |
| Homologene ID | 20100 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 105976 |
|---|
| RGD ID | 3143 |
|---|
| MedScan ID | 4644 |
|---|