| URN | urn:agi-llid:5879 |
|---|---|
| Total Entities | 0 |
| Connectivity | 3351 |
| Name | Rac1 |
| Description | ras-related C3 botulinum toxin substrate 1 |
| Notes | The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
| GO Molecular Function | GTPase activity |
|---|---|
| GTP-dependent protein binding | |
| enzyme binding | |
| thioesterase binding | |
| protein kinase binding | |
| Rab GTPase binding | |
| nucleotide binding | |
| GTP binding |
| GO Cellular Component | membrane |
|---|---|
| phagocytic cup | |
| extrinsic component of plasma membrane | |
| ruffle membrane | |
| Golgi membrane | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| cytoplasmic vesicle | |
| cytoplasmic membrane-bounded vesicle | |
| melanosome | |
| trans-Golgi network | |
| lamellipodium |
| GO Biological Process | Fc-gamma receptor signaling pathway involved in phagocytosis |
|---|---|
| regulation of defense response to virus by virus | |
| innate immune response | |
| Fc-epsilon receptor signaling pathway | |
| T cell costimulation | |
| mast cell chemotaxis | |
| cell proliferation | |
| GTP catabolic process | |
| regulation of respiratory burst | |
| positive regulation of phosphatidylinositol 3-kinase activity | |
| bone resorption | |
| negative regulation of interleukin-23 production | |
| blood coagulation | |
| platelet activation | |
| cochlea morphogenesis | |
| auditory receptor cell morphogenesis | |
| Wnt signaling pathway, planar cell polarity pathway | |
| cerebral cortex radially oriented cell migration | |
| embryonic olfactory bulb interneuron precursor migration | |
| dopaminergic neuron differentiation | |
| dendrite morphogenesis | |
| axon guidance | |
| dendrite development | |
| anatomical structure arrangement | |
| substrate adhesion-dependent cell spreading | |
| epithelial cell morphogenesis | |
| cellular component movement | |
| cell adhesion | |
| actin cytoskeleton organization | |
| actin filament organization | |
| actin filament polymerization | |
| positive regulation of actin filament polymerization | |
| intracellular signal transduction | |
| apoptotic signaling pathway | |
| small GTPase mediated signal transduction | |
| Rac protein signal transduction | |
| positive regulation of Rho protein signal transduction | |
| neurotrophin TRK receptor signaling pathway | |
| cell-matrix adhesion | |
| cell motility | |
| cell migration | |
| regulation of cell migration | |
| positive regulation of apoptotic process | |
| ruffle organization | |
| ruffle assembly | |
| lamellipodium assembly | |
| positive regulation of lamellipodium assembly | |
| cell-cell junction organization | |
| phagocytosis, engulfment | |
| engulfment of apoptotic cell | |
| chemotaxis | |
| response to wounding | |
| inflammatory response | |
| hyperosmotic response | |
| positive regulation of DNA replication | |
| positive regulation of protein phosphorylation | |
| regulation of hydrogen peroxide metabolic process | |
| negative regulation of receptor-mediated endocytosis | |
| anatomical structure morphogenesis | |
| endocytosis | |
| viral process | |
| cytoskeleton organization | |
| localization within membrane |
| Pathway | Tight Junction Assembly (Claudins) |
|---|---|
| Tight Junction Assembly (JAMs) | |
| Adherens Junction Assembly (Cadherins) | |
| Adherens Junction Assembly (Nectin) | |
| Dystrophin Glycoprotein Complex Signaling in Duchenne Muscular Dystrophy | |
| Ca2+ Overload in Duchenne Muscular Dystrophy | |
| Duchenne Muscular Dystrophy Overview | |
| IL6 Promotes Inflammation | |
| B-cell Chronic Lymphocytic Leukemia Overview | |
| Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Overview | |
| Breast Cancer Related to WNT Signaling Pathway | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to WNT Signaling Pathway | |
| Insulin Resistance in Hepatocytes | |
| Common Non-genomic Effects of Thyroid Hormones | |
| Proteins Involved in Pathogenesis of Melanoma | |
| B-cell Activation in Systemic Lupus Erythematosus | |
| Neutrophil and Macrophage Function in Systemic Lupus Erythematosus | |
| T-cell-Dependent B-cell Activation | |
| T-cell-Independent B-cell Activation | |
| Natural Killer Cell Activation through C-type Lectin-like Receptors | |
| Natural Killer Cell Activation through ITSM-Containing Receptors | |
| Natural Killer Cell Activation through ITAM-Containing Receptors | |
| Natural Killer Cell Inhibitory Receptor Signaling | |
| Natural Killer Cell Activation through Integrins and non-ITAM-Containing Receptors | |
| Toll-like Receptors Act through MYD88-TIRAP Signaling | |
| Natural Killer Cell Activation | |
| CFTR Up-regulates the Oxidative Stress in Airway Epithelium in Cystic Fibrosis | |
| Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension | |
| Smooth Muscle Cell Dysfunction in Pulmonary Arterial Hypertension | |
| BMP2 Activates Non-Canonical WNT Signaling in Pulmonary Artery Endothelial Cells | |
| BMP2 Activates WNT Signaling in Pulmonary Artery Smooth Muscle Cells | |
| Proteins Involved in Pathogenesis of Glioblastoma | |
| Proteins Involved in Pathogenesis of Glioma | |
| Proteins Involved in Pathogenesis of Astrocytoma | |
| Proteins Involved in Pathogenesis of Medulloblastoma | |
| CCR5 Signaling in Macrophages in HIV Type 1 Infection | |
| Macrophage Survival through CCR5 and CXCR4 Mediated Signaling in HIV Type 1 Infection | |
| TNF and IL1B Induce Metalloproteinase Synthesis | |
| IL1B-Induced Arthralgia in Osteoarthritis | |
| Osteoarthritis Overview | |
| Proteins Involved in Pathogenesis of Neuroblastoma | |
| Dysregulation of Endosomal Trafficking in Amyotrophic Lateral Sclerosis | |
| SOD1 Mutation in Amyotrophic Lateral Sclerosis | |
| Oxidative Stress in Amyotrophic Lateral Sclerosis | |
| Impairment of Microglia Inhibition by Motor Neuron in Amyotrophic Lateral Sclerosis | |
| Cytokine-Dependent Synovial Fibroblast Activation in Rheumatoid Arthritis | |
| Proteins Involved in Pathogenesis of Epilepsy | |
| B-cells Function in Systemic Scleroderma | |
| Role of Scavenger Receptor OLR1 in Inflammation-Related Endothelial Dysfunction in Atherosclerosis | |
| Nociception-related DRD2 expression targets | |
| Nociception-related IL1B expression targets | |
| GFs/TNF -> ion channels | |
| FGFR -> AP-1/CREB/CREBBP/ELK-SRF/MYC signaling | |
| PDGFR -> AP-1/MYC signaling | |
| VEGFR -> AP-1/CREB/MYC signaling | |
| HGFR -> AP-1/CREB/MYC signaling | |
| AngiopoietinR -> AP-1 signaling | |
| ErythropoietinR -> AP-1/CREB/MYC signaling | |
| ThrombopoietinR -> AP-1/CREB/ELK-SRF/MYC signaling | |
| EGFR -> AP-1/CREB/ELK-SRF/MYC signaling | |
| EGFR -> NCOR2 signaling | |
| FrizzledR -> JUN/PAX2 signaling | |
| T-cell receptor -> ATF/CREB signaling | |
| FcIgER -> ELK-SRF signaling | |
| TLR1/2/6 -> NF-kB signaling | |
| IL1R -> STAT3 signaling | |
| IL1R -> NF-kB signaling | |
| AGER -> CREB/SP1 signaling | |
| EGFR -> AP-1/ATF2 signaling | |
| EGFR/ERBB2 -> TP53 signaling | |
| EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG signaling | |
| KIT -> MITF signaling | |
| IGF1R -> MEF/MYOD/MYOG signaling | |
| GDNF -> HSF1 signaling | |
| NTRK -> AP-1/CREB/ELK-SRF/MYC/SMAD3/TP53 signaling | |
| FibronectinR -> NF-kB signaling | |
| FibronectinR -> AP-1/ELK-SRF/SREBF signaling | |
| EDG2 -> ELK-SRF signaling | |
| DopamineR2 -> AP-1/CREB/ELK-SRF signaling | |
| VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling | |
| VasopressinR1 -> CREB/ELK-SRF/AP-1/EGR signaling | |
| EndothelinRb -> AP-1/CREB/ELK-SRF signaling | |
| VasopressinR2 -> CREB/ELK-SRF/AP-1/EGR signaling | |
| VasopressinR2 -> MEF/MYOD/NFATC/MYOG signaling | |
| ThrombinR -> AP-1/CREB/ELK-SRF/SP1 signaling | |
| ROS and RNS in the Regulation of Vasoconstriction and Vasodilation | |
| ROS in Angiotensin-Mediated Cardiovascular Remodeling and Hypertrophy | |
| ROS in Triggering Vascular Inflammation | |
| WNT7A Expression Targets | |
| WNT1 Expression Targets | |
| WNT4 Expression Targets | |
| WNT3A Expression Targets | |
| TLR1/2/6 Expression Targets | |
| Fibronectin Expression Targets | |
| CD247 Expression Targets | |
| FCGR3A Expression Targets | |
| Dopamine/Gi Expression Targets | |
| S100A Expression Targets | |
| S100B Expression Targets | |
| S100P Expression Target | |
| HMGB1 Expression Targets | |
| TTR Expression Targets | |
| AREG/AP-1 Expression Targets | |
| AREG/NFATC Expression Target | |
| BTC/NFATC Expression Targets | |
| EGF/TP53 Expression Targets | |
| EREG/AP-1/ATF Expression Targets | |
| HBEGF/AP-1/ATF Expression Targets | |
| HBEGF/MEF/MYOD Expression Target | |
| HBEGF/TP53 Expression Targets | |
| NRG1/AP-1/ATF Expression Targets | |
| NRG1/MEF/MYOD Expression Targets | |
| NRG1/TP53 Expression Target | |
| TGFA/MEF/MYOD/NFATC Expression Targets | |
| TGFA/TP53 Expression Targets | |
| GDNF/HSF1 Expression Targets | |
| IGF2/MEF/MYOD Expression Targets | |
| CTGF/AP-1/CREB/MYC Expression Targets | |
| CTGF/NCOR2 Expression Target | |
| Erythropoietin/AP-1/MYC/CREB Expression Targets | |
| FLT3LG/AP-1/CREB/CREBBP Expression Targets | |
| GAS6/AP-1/CREB Expression Targets | |
| PGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| Thrombopoietin/AP-1/CREB/CREBBP/MYC Expression Targets | |
| AREG/CREB/CREBBP Expression Targets | |
| AREG/NCOR2 Expression Targets | |
| EGF/NCOR2 Expression Target | |
| EREG/CREB Expression Target | |
| HBEGF/CREB/MYC Expression Targets | |
| NRG1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| TGFA/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| FGF1/AP-1/CREB/ELK-SRF/MYC Expression Targets | |
| FGF1/NCOR2 Expression Target | |
| FGF2/NCOR2 Expression Targets | |
| FGF4/AP-1/MYC Expression Targets | |
| FGF7/AP-1/CREB/CREBBP/MYC Expression Targets | |
| FGF8/AP-1/CREB/MYC Expression Targets | |
| FGF9/AP-1/CREB/MYC Expression Targets | |
| FGF10/AP-1/CREB/CREBBP/MYC Expression Targets | |
| FGF18/AP-1/CREB Expression Targets | |
| FGF23/NCOR2 Expression Targets | |
| CSF1/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGFB/AP-1/CREB/MYC Expression Target | |
| PDGFC/CREB Expression Target | |
| PDGFD/AP-1 Expression Targets | |
| VEGFA/NCOR2 Expression Target | |
| ANGPT1/CREB/CREBBP Expression Targets | |
| ANGPT2/AP-1/CREBBP/MYC Expression Targets | |
| FIGF/AP-1 Expression Target | |
| FIGF/NCOR2 Expression Target | |
| F2 -> AP-1/CREB/ELK-SRF/SP1 Expression Targets | |
| PLG -> AP-1/CREB/ELK-SRF/SP1 Expression Targets | |
| AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets | |
| AVP/Gq -> CREB/ELK-SRF/AP-1/EGR Expression Targets | |
| AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets | |
| AVP/Gs -> CREB/ELK-SRF/AP-1/EGR Expression Targets | |
| EDN1 Expression Targets | |
| EDN3 Expression Targets | |
| IL16/ATF/CREB/CREBBP Expression Target | |
| CD8/ATF/CREB/CREBBP Expression Targets | |
| CD80/ATF/CREB/CREBBP Expression Targets | |
| CD86/ATF/CREB/CREBBP Expression Targets | |
| CD72/CREB/CREBBP Expression Targets | |
| PDCD1/ATF/CREB/CREBBP Expression Targets | |
| TCR/CREB/CREBBP/ATF Expression Targets | |
| FGF2/AP-1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| IL1A Expression Targets | |
| WNT5A Expression Targets | |
| EGF/AP-1/ATF Expression Targets | |
| EGF/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| EGF/MEF/MYOD/NFATC Expression Targets | |
| HGF/AP-1/CREB/ELK-SRF/MYC Expression Targets | |
| IGF1/MEF/MYOD/MYOG Expression Targets | |
| Insulin/MEF/MYOD Expression Targets | |
| KITLG/AP-1/CREB/CREBBP/MYC Expression Targets | |
| LPA Expression Targets | |
| PDGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| TGFA/AP-1/ATF Expression Targets | |
| VEGFA/AP-1/CREBBP/MYC Expression Targets | |
| IL1B Expression Targets | |
| BTC/AP-1/ATF/CREB Expression Targets | |
| Wnt signaling, the planar cell polarity pathway | |
| p38 MAPK signaling pathway | |
| c-Jun N-terminal kinases MAPK signaling pathway | |
| the planar cell polarity Wnt signaling pathway | |
| c-Jun N-terminal kinases MAPK signaling pathway | |
| p38 MAPK signaling pathway | |
| the planar cell polarity Wnt signaling pathway | |
| insulin responsive facilitative sugar transporter mediated glucose transport pathway |
| Group | Rac/CDC42 |
|---|---|
| Fc-gamma receptor signaling pathway involved in phagocytosis | |
| regulation of defense response to virus by virus | |
| innate immune response | |
| Fc-epsilon receptor signaling pathway | |
| T cell costimulation | |
| mast cell chemotaxis | |
| cell proliferation | |
| GTP catabolic process | |
| GTPase activity | |
| regulation of respiratory burst | |
| positive regulation of phosphatidylinositol 3-kinase activity | |
| bone resorption | |
| negative regulation of interleukin-23 production | |
| blood coagulation | |
| platelet activation | |
| cochlea morphogenesis | |
| auditory receptor cell morphogenesis | |
| Wnt signaling pathway, planar cell polarity pathway | |
| cerebral cortex radially oriented cell migration | |
| embryonic olfactory bulb interneuron precursor migration | |
| dopaminergic neuron differentiation | |
| dendrite morphogenesis | |
| axon guidance | |
| dendrite development | |
| anatomical structure arrangement | |
| substrate adhesion-dependent cell spreading | |
| epithelial cell morphogenesis | |
| cellular component movement | |
| cell adhesion | |
| actin cytoskeleton organization | |
| actin filament organization | |
| actin filament polymerization | |
| positive regulation of actin filament polymerization | |
| intracellular signal transduction | |
| apoptotic signaling pathway | |
| small GTPase mediated signal transduction | |
| Rac protein signal transduction | |
| positive regulation of Rho protein signal transduction | |
| neurotrophin TRK receptor signaling pathway | |
| cell-matrix adhesion | |
| cell motility | |
| cell migration | |
| regulation of cell migration | |
| positive regulation of apoptotic process | |
| ruffle organization | |
| ruffle assembly | |
| lamellipodium assembly | |
| positive regulation of lamellipodium assembly | |
| cell-cell junction organization | |
| phagocytosis, engulfment | |
| engulfment of apoptotic cell | |
| chemotaxis | |
| response to wounding | |
| inflammatory response | |
| hyperosmotic response | |
| positive regulation of DNA replication | |
| positive regulation of protein phosphorylation | |
| regulation of hydrogen peroxide metabolic process | |
| negative regulation of receptor-mediated endocytosis | |
| anatomical structure morphogenesis | |
| endocytosis | |
| viral process | |
| cytoskeleton organization | |
| localization within membrane | |
| GTP-dependent protein binding | |
| enzyme binding | |
| thioesterase binding | |
| protein kinase binding | |
| Rab GTPase binding | |
| nucleotide binding | |
| GTP binding | |
| membrane | |
| phagocytic cup | |
| extrinsic component of plasma membrane | |
| ruffle membrane | |
| Golgi membrane | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| cytoplasmic vesicle | |
| cytoplasmic membrane-bounded vesicle | |
| melanosome | |
| trans-Golgi network | |
| lamellipodium | |
| Secreted proteins | |
| Biofluids assayable substances |
| Source | Curated |
|---|---|
| ResNet | |
| GO component | |
| RGD modified |
| LocusLink ID | 5879 |
|---|---|
| 19353 | |
| 363875 | |
| 100781 | |
| 171377 | |
| 52352 | |
| 281440 | |
| 327204 | |
| 393898 |
| Cell Localization | Cytoplasm |
|---|---|
| Cell membrane | |
| Melanosome | |
| Plasma membrane |
| GO ID | 0005525 |
|---|---|
| 0030742 | |
| 0003924 | |
| 0017137 | |
| 0019899 | |
| 0019901 | |
| 0031996 | |
| 0038095 | |
| 0038096 | |
| 0031295 | |
| 0060071 | |
| 0030036 | |
| 0030041 | |
| 0048532 | |
| 0009653 | |
| 0097190 | |
| 0002093 | |
| 0007411 | |
| 0007596 | |
| 0045453 | |
| 0007155 | |
| 0048870 | |
| 0008283 | |
| 0045216 | |
| 0007160 | |
| 0006928 | |
| 0021799 | |
| 0090103 | |
| 0048813 | |
| 0071542 | |
| 0021831 | |
| 0043652 | |
| 0003382 | |
| 0006972 | |
| 0006954 | |
| 0045087 | |
| 0035556 | |
| 0030032 | |
| 0051668 | |
| 0002551 | |
| 0032707 | |
| 0048261 | |
| 0048011 | |
| 0030168 | |
| 0045740 | |
| 0035025 | |
| 0030838 | |
| 0043065 | |
| 0010592 | |
| 0043552 | |
| 0001934 | |
| 0030334 | |
| 0050690 | |
| 0010310 | |
| 0060263 | |
| 0009611 | |
| 0097178 | |
| 0031529 | |
| 0007264 | |
| 0034446 | |
| 0016032 | |
| 0000139 | |
| 0005829 | |
| 0019897 | |
| 0030027 | |
| 0042470 | |
| 0001891 | |
| 0005886 | |
| 0032587 | |
| 0005802 | |
| 0000166 | |
| 0006184 | |
| 0007015 | |
| 0016477 | |
| 0006935 | |
| 0007010 | |
| 0016358 | |
| 0006897 | |
| 0006911 | |
| 0042995 | |
| 0005737 | |
| 0016023 | |
| 0031410 | |
| 0005622 | |
| 0016020 | |
| 0016601 | |
| 0006915 | |
| 0051056 | |
| 0008624 | |
| 0023034 | |
| 0005624 | |
| 0005515 | |
| 0015031 | |
| 0050775 | |
| 0005579 |
| Alias | MIG5 |
|---|---|
| Rac-1 | |
| TC-25 | |
| p21-Rac1 | |
| ras-related C3 botulinum toxin substrate 1 | |
| ras-like protein TC25 | |
| cell migration-inducing gene 5 protein | |
| AL023026 | |
| D5Ertd559e | |
| rho family, small GTP binding protein Rac1 | |
| ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1) | |
| TC25 | |
| ras-related C3 botulinum toxin substrate 1 isoform Rac I | |
| RAS-related C3 botulinum substrate I | |
| ras-related C3 botulinum toxin substrate 1 isoform Rac1 | |
| RAC1_HUMAN | |
| rho family, small GTP binding Rac | |
| RAS-related C3 botulinum substrate 1 | |
| ras-related C3 botulinum toxin substrate 1 isoform Rac1b | |
| ras-related C3 botulinum toxin substrate I | |
| small gtp binding protein rac1 | |
| rac1 GTP binding protein | |
| rac1 GTP-binding protein | |
| migration-inducing protein 5 | |
| rho family, small GTP binding protein Rac I | |
| DNA segment, Chr 5, ERATO Doi 559, expressed | |
| Rac1B | |
| rac1c | |
| GTP-binding protein rac I | |
| GTP-binding protein rac1 | |
| LOC136000 | |
| LOC155330 | |
| Rac(V12) | |
| Rac1 | |
| MGC111543 | |
| Rac I | |
| p21-Rac I | |
| OTTMUSP00000022620 | |
| migration-inducing protein V | |
| migration-inducing gene 5 | |
| ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | |
| Ras-like protein TC25 | |
| expressed sequence AL023026 | |
| isoform rac1b | |
| rac1b splicing isoform | |
| splicing isoform rac1b | |
| MGC55823 | |
| chromosome | |
| fd16e02 | |
| scaffold | |
| wu:fd16e02 | |
| zgc:55823 | |
| zgc:55917 | |
| zgc:86934 | |
| RAC related | |
| RAC related (21.5 kD) | |
| RAC related (21.5 kD) (ced-10) | |
| ced-10 | |
| similar to CEll Death abnormality CED-10 | |
| similar to CEll Death abnormality CED-10, RAC related (21.5 kD) (ced-10) |
| Mouse chromosome position | 5 82.22 cM |
|---|---|
| 5 82.0 cM |
| OMIM ID | 602048 |
|---|
| Rat chromosome position | 12p11 |
|---|
| Hugo ID | 9801 |
|---|
| Human chromosome position | 7p22 |
|---|
| Swiss-Prot Accession | A4D2P1 |
|---|---|
| P63000 | |
| A4D2P0 | |
| K7Q7T7 | |
| P63001 | |
| Q6RUV5 | |
| O95501 | |
| P15154 | |
| Q9BTB4 | |
| Q3Y4D3 | |
| Q5JAA8 | |
| Q59FQ0 | |
| Q3TLP8 | |
| Q8BPG5 | |
| Q8C4N8 | |
| Q9D859 | |
| Q923X0 | |
| AAB22206 |
| PIR ID | A60347 |
|---|---|
| A34788 |
| Unigene ID | Hs.413812 |
|---|---|
| Mm.292510 | |
| Mm.469963 | |
| Mm.475073 | |
| Rn.29157 | |
| Mm.342177 | |
| Mm.466548 | |
| Mm.74208 | |
| Hs.632900 | |
| Hs.633454 | |
| Hs.551925 | |
| Mm.432479 | |
| Bt.75763 | |
| Dr.117150 | |
| Dr.4711 |
| KEGG ID | hsa:5879 |
|---|---|
| mmu:19353 | |
| rno:363875 |
| Swiss-Prot ID | RAC1_RAT |
|---|---|
| RAC1_MOUSE | |
| RAC1_HUMAN | |
| A4D2P0_HUMAN | |
| A4D2P1_HUMAN |
| Ensembl ID | ENSG00000136238 |
|---|---|
| ENSP00000258737 | |
| ENST00000348035 | |
| ENSMUSG00000001847 | |
| ENSMUSP00000079380 | |
| ENSMUST00000080537 | |
| ENSMUSP00000098058 | |
| ENSMUST00000100489 | |
| ENSRNOG00000001068 | |
| ENSRNOP00000001417 | |
| ENSRNOT00000001417 |
| Homologene ID | 69035 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus | |
| Bos taurus | |
| Danio rerio |
| MGI ID | 97845 |
|---|---|
| 2141016 | |
| 1261850 |
| RGD ID | 619755 |
|---|
| MedScan ID | 5879 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00010271 |
|---|---|
| IPI00219675 | |
| IPI00422092 | |
| IPI00761613 | |
| IPI00555566 | |
| IPI00394837 | |
| IPI00127408 | |
| IPI00780227 |
| KEGG pathway | Adherens junction |
|---|---|
| Axon guidance | |
| B cell receptor signaling pathway | |
| Colorectal cancer | |
| Fc epsilon RI signaling pathway | |
| Focal adhesion | |
| Leukocyte transendothelial migration | |
| MAPK signaling pathway | |
| Natural killer cell mediated cytotoxicity | |
| Pancreatic cancer | |
| Regulation of actin cytoskeleton | |
| Renal cell carcinoma | |
| Toll-like receptor signaling pathway | |
| VEGF signaling pathway | |
| Wnt signaling pathway |
| Microarray ID | 101555_at |
|---|
| Homo sapiens Chromosome position | 7p22 |
|---|
| FunctionalClass | GTP binding |
|---|---|
| GTP-dependent protein binding | |
| GTPase | |
| nucleotide binding | |
| protein binding |
| Bos taurus Chromosome position | 25 |
|---|
| Mus musculus Chromosome position | 5 82.0 cM |
|---|---|
| 5 |
| Rattus norvegicus Chromosome position | 12p11 |
|---|