| URN | urn:agi-llid:3243 |
|---|---|
| Total Entities | 0 |
| Connectivity | 1269 |
| Name | Shh |
| Description | sonic hedgehog |
| Notes | This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly. [provided by RefSeq] |
| Ariadne Ontology | SHH |
|---|---|
| Secreted proteins | |
| Biofluids assayable substances |
| GO Molecular Function | morphogen activity |
|---|---|
| receptor binding | |
| glycoprotein binding | |
| patched binding | |
| laminin-1 binding | |
| glycosaminoglycan binding | |
| calcium ion binding | |
| zinc ion binding | |
| hydrolase activity | |
| peptidase activity | |
| signal transducer activity |
| GO Cellular Component | membrane |
|---|---|
| extracellular matrix | |
| extracellular region | |
| membrane raft | |
| plasma membrane | |
| cell surface | |
| endoplasmic reticulum | |
| Golgi apparatus | |
| transport vesicle | |
| nucleus | |
| axon | |
| dendrite | |
| neuronal cell body | |
| extracellular space |
| GO Biological Process | cell proliferation |
|---|---|
| positive regulation of penile erection | |
| cell communication | |
| cell death | |
| epithelial-mesenchymal signaling involved in prostate gland development | |
| mesenchymal smoothened signaling pathway involved in prostate gland development | |
| regulation of epithelial cell proliferation involved in prostate gland development | |
| positive regulation of epithelial cell proliferation involved in prostate gland development | |
| regulation of mesenchymal cell proliferation involved in prostate gland development | |
| cell-cell signaling | |
| epithelial-mesenchymal cell signaling | |
| negative regulation of Wnt receptor signaling pathway | |
| negative regulation of canonical Wnt receptor signaling pathway | |
| positive regulation of smoothened signaling pathway | |
| positive regulation of Wnt receptor signaling pathway | |
| regulation of nodal signaling pathway involved in determination of lateral mesoderm left-right asymmetry | |
| signal transduction | |
| regulation of cell proliferation | |
| smoothened signaling pathway | |
| smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation | |
| canonical Wnt receptor signaling pathway | |
| negative regulation of proteasomal ubiquitin-dependent protein catabolic process | |
| positive regulation of transcription, DNA-dependent | |
| positive regulation of transcription from RNA polymerase II promoter | |
| negative regulation of transcription from RNA polymerase II promoter | |
| negative regulation of transcription elongation from RNA polymerase II promoter | |
| regulation of transcription, DNA-dependent | |
| positive regulation of hh target transcription factor activity | |
| negative regulation of cell differentiation | |
| negative regulation of alpha-beta T cell differentiation | |
| negative regulation of ureter smooth muscle cell differentiation | |
| negative regulation of kidney smooth muscle cell differentiation | |
| negative regulation of T cell proliferation | |
| negative regulation of cell migration | |
| negative regulation of apoptotic process | |
| positive regulation of cell division | |
| positive regulation of cell differentiation | |
| positive regulation of cell proliferation | |
| positive regulation of skeletal muscle cell proliferation | |
| positive regulation of mesenchymal cell proliferation | |
| positive regulation of mesenchymal cell proliferation involved in ureter development | |
| positive regulation of neuroblast proliferation | |
| positive regulation of cerebellar granule cell precursor proliferation | |
| positive regulation of oligodendrocyte progenitor proliferation | |
| positive regulation of immature T cell proliferation in thymus | |
| positive regulation of alpha-beta T cell differentiation | |
| positive regulation of T cell differentiation in thymus | |
| positive regulation of neuron differentiation | |
| positive regulation of oligodendrocyte differentiation | |
| positive regulation of photoreceptor cell differentiation | |
| positive regulation of striated muscle cell differentiation | |
| positive regulation of kidney smooth muscle cell differentiation | |
| positive regulation of ureter smooth muscle cell differentiation | |
| positive regulation of protein import into nucleus | |
| regulation of protein localization to nucleus | |
| regulation of epithelial cell differentiation | |
| regulation of apoptotic process | |
| cell fate commitment | |
| cell development | |
| cell fate specification | |
| osteoblast development | |
| stem cell development | |
| oligodendrocyte development | |
| vasculogenesis | |
| vasculogenesis involved in coronary vascular morphogenesis | |
| lymphoid progenitor cell differentiation | |
| T cell differentiation in thymus | |
| oligodendrocyte differentiation | |
| Bergmann glial cell differentiation | |
| striated muscle cell differentiation | |
| myoblast differentiation | |
| myotube differentiation | |
| ventral spinal cord interneuron specification | |
| neuron fate commitment | |
| CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | |
| androgen metabolic process | |
| neural crest cell migration | |
| establishment of cell polarity | |
| cellular response to lithium ion | |
| apoptotic process | |
| protein localization to nucleus | |
| intermediate filament organization | |
| positive thymic T cell selection | |
| negative thymic T cell selection | |
| mesenchymal cell proliferation | |
| epithelial cell proliferation involved in salivary gland morphogenesis | |
| mesenchymal cell proliferation involved in lung development | |
| metanephric mesenchymal cell proliferation involved in metanephros development | |
| neuroblast proliferation | |
| response to organic nitrogen | |
| response to estradiol stimulus | |
| response to retinoic acid | |
| response to ethanol | |
| axon guidance | |
| response to hypoxia | |
| response to axon injury | |
| negative regulation of gene expression | |
| negative regulation of protein catabolic process | |
| negative regulation of cholesterol efflux | |
| regulation of prostatic bud formation | |
| positive regulation of sclerotome development | |
| positive regulation of skeletal muscle tissue development | |
| positive regulation of gene expression | |
| regulation of gene expression | |
| regulation of proteolysis | |
| multicellular organismal development | |
| anatomical structure development | |
| pattern specification process | |
| anatomical structure formation involved in morphogenesis | |
| developmental growth | |
| prostate gland development | |
| male genitalia development | |
| male genitalia morphogenesis | |
| prostatic bud formation | |
| branching involved in prostate gland morphogenesis | |
| prostate epithelial cord elongation | |
| primary prostatic bud elongation | |
| embryonic digit morphogenesis | |
| embryonic foregut morphogenesis | |
| heart looping | |
| embryonic digestive tract morphogenesis | |
| branching morphogenesis of a tube | |
| limb bud formation | |
| hair follicle morphogenesis | |
| angiogenesis | |
| lung lobe morphogenesis | |
| fungiform papilla morphogenesis | |
| fungiform papilla formation | |
| hindgut morphogenesis | |
| organ formation | |
| branching involved in salivary gland morphogenesis | |
| formation of anatomical boundary | |
| patterning of blood vessels | |
| branching involved in ureteric bud morphogenesis | |
| epithelial tube branching involved in lung morphogenesis | |
| bud outgrowth involved in lung branching | |
| neural tube formation | |
| salivary gland cavitation | |
| embryo development | |
| forebrain development | |
| midbrain development | |
| ventral midline development | |
| palate development | |
| hindbrain development | |
| fungiform papilla development | |
| somite development | |
| inner ear development | |
| central nervous system development | |
| vasculature development | |
| renal system development | |
| embryonic skeletal system development | |
| artery development | |
| respiratory tube development | |
| pancreas development | |
| embryonic organ development | |
| lung development | |
| trachea development | |
| kidney development | |
| heart development | |
| tongue development | |
| camera-type eye development | |
| metanephros development | |
| thyroid gland development | |
| thymus development | |
| right lung development | |
| left lung development | |
| ectoderm development | |
| multicellular structure septum development | |
| digestive tract mesoderm development | |
| lung epithelium development | |
| hair follicle development | |
| skin development | |
| lung-associated mesenchyme development | |
| striated muscle tissue development | |
| limb development | |
| embryonic pattern specification | |
| dorsal-ventral pattern formation | |
| anterior-posterior pattern specification | |
| telencephalon regionalization | |
| spinal cord dorsal-ventral patterning | |
| dorsal-ventral neural tube patterning | |
| determination of left-right symmetry | |
| determination of left-right asymmetry in lateral mesoderm | |
| digestive tract morphogenesis | |
| embryonic morphogenesis | |
| embryonic limb morphogenesis | |
| embryonic forelimb morphogenesis | |
| embryonic hindlimb morphogenesis | |
| odontogenesis | |
| lung morphogenesis | |
| trachea morphogenesis | |
| tongue morphogenesis | |
| odontogenesis of dentin-containing tooth | |
| blood coagulation | |
| endocytosis | |
| proteolysis | |
| intein-mediated protein splicing |
| Pathway | EDA Expression Targets |
|---|---|
| NOTCH Expression Targets | |
| pancreatic cancer pathway | |
| pancreatic cancer pathway |
| Group | SHH |
|---|---|
| cell proliferation | |
| positive regulation of penile erection | |
| cell communication | |
| cell death | |
| epithelial-mesenchymal signaling involved in prostate gland development | |
| mesenchymal smoothened signaling pathway involved in prostate gland development | |
| regulation of epithelial cell proliferation involved in prostate gland development | |
| positive regulation of epithelial cell proliferation involved in prostate gland development | |
| regulation of mesenchymal cell proliferation involved in prostate gland development | |
| cell-cell signaling | |
| epithelial-mesenchymal cell signaling | |
| negative regulation of Wnt receptor signaling pathway | |
| negative regulation of canonical Wnt receptor signaling pathway | |
| positive regulation of smoothened signaling pathway | |
| positive regulation of Wnt receptor signaling pathway | |
| regulation of nodal signaling pathway involved in determination of lateral mesoderm left-right asymmetry | |
| signal transduction | |
| regulation of cell proliferation | |
| smoothened signaling pathway | |
| smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation | |
| canonical Wnt receptor signaling pathway | |
| negative regulation of proteasomal ubiquitin-dependent protein catabolic process | |
| positive regulation of transcription, DNA-dependent | |
| positive regulation of transcription from RNA polymerase II promoter | |
| negative regulation of transcription from RNA polymerase II promoter | |
| negative regulation of transcription elongation from RNA polymerase II promoter | |
| regulation of transcription, DNA-dependent | |
| positive regulation of hh target transcription factor activity | |
| negative regulation of cell differentiation | |
| negative regulation of alpha-beta T cell differentiation | |
| negative regulation of ureter smooth muscle cell differentiation | |
| negative regulation of kidney smooth muscle cell differentiation | |
| negative regulation of T cell proliferation | |
| negative regulation of cell migration | |
| negative regulation of apoptotic process | |
| positive regulation of cell division | |
| positive regulation of cell differentiation | |
| positive regulation of cell proliferation | |
| positive regulation of skeletal muscle cell proliferation | |
| positive regulation of mesenchymal cell proliferation | |
| positive regulation of mesenchymal cell proliferation involved in ureter development | |
| positive regulation of neuroblast proliferation | |
| positive regulation of cerebellar granule cell precursor proliferation | |
| positive regulation of oligodendrocyte progenitor proliferation | |
| positive regulation of immature T cell proliferation in thymus | |
| positive regulation of alpha-beta T cell differentiation | |
| positive regulation of T cell differentiation in thymus | |
| positive regulation of neuron differentiation | |
| positive regulation of oligodendrocyte differentiation | |
| positive regulation of photoreceptor cell differentiation | |
| positive regulation of striated muscle cell differentiation | |
| positive regulation of kidney smooth muscle cell differentiation | |
| positive regulation of ureter smooth muscle cell differentiation | |
| positive regulation of protein import into nucleus | |
| regulation of protein localization to nucleus | |
| regulation of epithelial cell differentiation | |
| regulation of apoptotic process | |
| cell fate commitment | |
| cell development | |
| cell fate specification | |
| osteoblast development | |
| stem cell development | |
| oligodendrocyte development | |
| vasculogenesis | |
| vasculogenesis involved in coronary vascular morphogenesis | |
| lymphoid progenitor cell differentiation | |
| T cell differentiation in thymus | |
| oligodendrocyte differentiation | |
| Bergmann glial cell differentiation | |
| striated muscle cell differentiation | |
| myoblast differentiation | |
| myotube differentiation | |
| ventral spinal cord interneuron specification | |
| neuron fate commitment | |
| CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | |
| androgen metabolic process | |
| neural crest cell migration | |
| establishment of cell polarity | |
| cellular response to lithium ion | |
| apoptotic process | |
| protein localization to nucleus | |
| intermediate filament organization | |
| positive thymic T cell selection | |
| negative thymic T cell selection | |
| mesenchymal cell proliferation | |
| epithelial cell proliferation involved in salivary gland morphogenesis | |
| mesenchymal cell proliferation involved in lung development | |
| metanephric mesenchymal cell proliferation involved in metanephros development | |
| neuroblast proliferation | |
| response to organic nitrogen | |
| response to estradiol stimulus | |
| response to retinoic acid | |
| response to ethanol | |
| axon guidance | |
| response to hypoxia | |
| response to axon injury | |
| negative regulation of gene expression | |
| negative regulation of protein catabolic process | |
| negative regulation of cholesterol efflux | |
| regulation of prostatic bud formation | |
| positive regulation of sclerotome development | |
| positive regulation of skeletal muscle tissue development | |
| positive regulation of gene expression | |
| regulation of gene expression | |
| regulation of proteolysis | |
| multicellular organismal development | |
| anatomical structure development | |
| pattern specification process | |
| anatomical structure formation involved in morphogenesis | |
| developmental growth | |
| prostate gland development | |
| male genitalia development | |
| male genitalia morphogenesis | |
| prostatic bud formation | |
| branching involved in prostate gland morphogenesis | |
| prostate epithelial cord elongation | |
| primary prostatic bud elongation | |
| embryonic digit morphogenesis | |
| embryonic foregut morphogenesis | |
| heart looping | |
| embryonic digestive tract morphogenesis | |
| branching morphogenesis of a tube | |
| limb bud formation | |
| hair follicle morphogenesis | |
| angiogenesis | |
| lung lobe morphogenesis | |
| fungiform papilla morphogenesis | |
| fungiform papilla formation | |
| hindgut morphogenesis | |
| organ formation | |
| branching involved in salivary gland morphogenesis | |
| formation of anatomical boundary | |
| patterning of blood vessels | |
| branching involved in ureteric bud morphogenesis | |
| epithelial tube branching involved in lung morphogenesis | |
| bud outgrowth involved in lung branching | |
| neural tube formation | |
| salivary gland cavitation | |
| embryo development | |
| forebrain development | |
| midbrain development | |
| ventral midline development | |
| palate development | |
| hindbrain development | |
| fungiform papilla development | |
| somite development | |
| inner ear development | |
| central nervous system development | |
| vasculature development | |
| renal system development | |
| embryonic skeletal system development | |
| artery development | |
| respiratory tube development | |
| pancreas development | |
| embryonic organ development | |
| lung development | |
| trachea development | |
| kidney development | |
| heart development | |
| tongue development | |
| camera-type eye development | |
| metanephros development | |
| thyroid gland development | |
| thymus development | |
| right lung development | |
| left lung development | |
| ectoderm development | |
| multicellular structure septum development | |
| digestive tract mesoderm development | |
| lung epithelium development | |
| hair follicle development | |
| skin development | |
| lung-associated mesenchyme development | |
| striated muscle tissue development | |
| limb development | |
| embryonic pattern specification | |
| dorsal-ventral pattern formation | |
| anterior-posterior pattern specification | |
| telencephalon regionalization | |
| spinal cord dorsal-ventral patterning | |
| dorsal-ventral neural tube patterning | |
| determination of left-right symmetry | |
| determination of left-right asymmetry in lateral mesoderm | |
| digestive tract morphogenesis | |
| embryonic morphogenesis | |
| embryonic limb morphogenesis | |
| embryonic forelimb morphogenesis | |
| embryonic hindlimb morphogenesis | |
| odontogenesis | |
| lung morphogenesis | |
| trachea morphogenesis | |
| tongue morphogenesis | |
| odontogenesis of dentin-containing tooth | |
| blood coagulation | |
| endocytosis | |
| proteolysis | |
| intein-mediated protein splicing | |
| morphogen activity | |
| receptor binding | |
| glycoprotein binding | |
| patched binding | |
| laminin-1 binding | |
| glycosaminoglycan binding | |
| calcium ion binding | |
| zinc ion binding | |
| hydrolase activity | |
| peptidase activity | |
| signal transducer activity | |
| membrane | |
| extracellular matrix | |
| extracellular region | |
| membrane raft | |
| plasma membrane | |
| cell surface | |
| endoplasmic reticulum | |
| Golgi apparatus | |
| transport vesicle | |
| nucleus | |
| axon | |
| dendrite | |
| neuronal cell body | |
| extracellular space | |
| Secreted proteins | |
| Biofluids assayable substances |
| MedScan ID | 3243 |
|---|
| Hugo ID | 10848 |
|---|
| Human chromosome position | 7q36 |
|---|
| LocusLink ID | 3243 |
|---|---|
| 6469 | |
| 20423 | |
| 29499 |
| Alias | TPT |
|---|---|
| HHG1 | |
| HLP3 | |
| HPE3 | |
| SMMCI | |
| TPTPS | |
| MCOPCB5 | |
| tcag7.582 | |
| sonic hedgehog protein | |
| sonic hedgehog homolog | |
| Hx | |
| Dsh | |
| Hxl3 | |
| M100081 | |
| 9530036O11Rik | |
| HHG-1 | |
| short digits | |
| hemimelic extra toes | |
| Vhh-1 | |
| Triphalangeal thumb-polysyndactyly syndrome protein | |
| short digits mutant | |
| Shh | |
| sonic hedgehog | |
| Sonic hedgehog , human homolog of | |
| Triphalangeal thumb-polysyndactyly syndrome gene | |
| sonic hedgehog homolog (Drosophila) | |
| holoprosencephaly 3 | |
| Histocompatibility X antigen | |
| HHG I | |
| OTTMUSP00000023583 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600725 |
|---|---|
| 142945 | |
| 611638 | |
| 269160 | |
| 147250 | |
| 120200 | |
| 174500 |
| Unigene ID | Hs.164537 |
|---|---|
| Mm.57202 | |
| Rn.10432 |
| KEGG ID | hsa:6469 |
|---|---|
| mmu:20423 | |
| rno:29499 |
| Swiss-Prot Accession | Q15465 |
|---|---|
| Q62226 | |
| Q63673 | |
| A4D247 | |
| Q75MC9 | |
| Q8C765 | |
| Q9R179 |
| GO ID | 0005509 |
|---|---|
| 0001948 | |
| 0005539 | |
| 0043237 | |
| 0016015 | |
| 0005113 | |
| 0008233 | |
| 0004871 | |
| 0008270 | |
| 0060020 | |
| 0043369 | |
| 0033077 | |
| 0008209 | |
| 0009952 | |
| 0006915 | |
| 0060840 | |
| 0007411 | |
| 0007596 | |
| 0060445 | |
| 0001658 | |
| 0048754 | |
| 0060447 | |
| 0043010 | |
| 0060070 | |
| 0048468 | |
| 0001708 | |
| 0007267 | |
| 0071285 | |
| 0007417 | |
| 0003140 | |
| 0007502 | |
| 0021904 | |
| 0009953 | |
| 0007398 | |
| 0009790 | |
| 0048557 | |
| 0042733 | |
| 0048617 | |
| 0035115 | |
| 0035116 | |
| 0030326 | |
| 0009880 | |
| 0048706 | |
| 0006897 | |
| 0060664 | |
| 0060738 | |
| 0030010 | |
| 0030900 | |
| 0048859 | |
| 0031069 | |
| 0007507 | |
| 0001947 | |
| 0030902 | |
| 0007442 | |
| 0048839 | |
| 0016539 | |
| 0045109 | |
| 0060459 | |
| 0060174 | |
| 0030324 | |
| 0060428 | |
| 0060463 | |
| 0060484 | |
| 0002320 | |
| 0030539 | |
| 0048808 | |
| 0060916 | |
| 0060783 | |
| 0072136 | |
| 0001656 | |
| 0030901 | |
| 0080125 | |
| 0045445 | |
| 0014902 | |
| 0042130 | |
| 0046639 | |
| 0043066 | |
| 0090090 | |
| 0045596 | |
| 0030336 | |
| 0090370 | |
| 2000357 | |
| 0032435 | |
| 0034244 | |
| 0000122 | |
| 2000062 | |
| 0045060 | |
| 0001755 | |
| 0001841 | |
| 0007405 | |
| 0048663 | |
| 0042475 | |
| 0014003 | |
| 0048645 | |
| 0002076 | |
| 0060021 | |
| 0031016 | |
| 0007389 | |
| 0001569 | |
| 0033089 | |
| 0030177 | |
| 0046638 | |
| 0051781 | |
| 0008284 | |
| 0060769 | |
| 0007228 | |
| 0033092 | |
| 2000358 | |
| 2000729 | |
| 0002052 | |
| 0048714 | |
| 0070447 | |
| 0060406 | |
| 0046534 | |
| 0042307 | |
| 0061189 | |
| 0014858 | |
| 0048643 | |
| 0045880 | |
| 0051155 | |
| 0045944 | |
| 0045893 | |
| 2000063 | |
| 0045059 | |
| 0060516 | |
| 0060523 | |
| 0030850 | |
| 0034504 | |
| 0006508 | |
| 0042127 | |
| 0030856 | |
| 0060782 | |
| 1900175 | |
| 0060685 | |
| 1900180 | |
| 0030162 | |
| 0072001 | |
| 0048678 | |
| 0032355 | |
| 0045471 | |
| 0001666 | |
| 0010243 | |
| 0032526 | |
| 0060458 | |
| 0060662 | |
| 0043588 | |
| 0007224 | |
| 0021938 | |
| 0061053 | |
| 0048864 | |
| 0021978 | |
| 0048538 | |
| 0030878 | |
| 0043587 | |
| 0060439 | |
| 0001570 | |
| 0007418 | |
| 0021521 | |
| 0005794 | |
| 0009986 | |
| 0005783 | |
| 0031012 | |
| 0005615 | |
| 0045121 | |
| 0005634 | |
| 0005886 | |
| 0030133 | |
| 0016787 | |
| 0048856 | |
| 0048646 | |
| 0001525 | |
| 0060442 | |
| 0007154 | |
| 0008219 | |
| 0045165 | |
| 0008283 | |
| 0007368 | |
| 0048589 | |
| 0048546 | |
| 0048598 | |
| 0048568 | |
| 0060441 | |
| 0060684 | |
| 0061196 | |
| 0061198 | |
| 0061197 | |
| 0001942 | |
| 0001822 | |
| 0060173 | |
| 0060425 | |
| 0010463 | |
| 0007275 | |
| 0030178 | |
| 0010629 | |
| 0042177 | |
| 0042476 | |
| 0048709 | |
| 0045597 | |
| 0021940 | |
| 0010628 | |
| 0002053 | |
| 0045666 | |
| 0060513 | |
| 0042981 | |
| 0060768 | |
| 0010468 | |
| 0006355 | |
| 0030323 | |
| 0007165 | |
| 0021513 | |
| 0051146 | |
| 0014706 | |
| 0043586 | |
| 0060438 | |
| 0001944 | |
| 0060979 | |
| 0030424 | |
| 0030425 | |
| 0005576 | |
| 0016020 | |
| 0043025 | |
| 0005102 | |
| 0016563 | |
| 0048314 | |
| 0010553 | |
| 0051151 | |
| 0010552 | |
| 0051152 | |
| 0045449 | |
| 0005624 | |
| 0043193 |
| PIR ID | A49425 |
|---|---|
| B53193 |
| Swiss-Prot ID | SHH_HUMAN |
|---|---|
| SHH_MOUSE | |
| SHH_RAT |
| Cell Localization | Secreted |
|---|---|
| extracellular space | |
| Cell membrane | |
| Extracellular |
| IPI ID | IPI00017480 |
|---|---|
| IPI00123314 | |
| IPI00211101 | |
| IPI00893003 | |
| IPI00892712 | |
| IPI00894434 |
| Mouse chromosome position | 5 16.0 cM |
|---|
| Rat chromosome position | 4q11 |
|---|
| Homologene ID | 30961 |
|---|
| MGI ID | 98297 |
|---|
| RGD ID | 3673 |
|---|
| Primary Cell Localization | Extracellular |
|---|