| URN | urn:agi-llid:22801 |
|---|---|
| Total Entities | 0 |
| Connectivity | 36 |
| Name | Itga11 |
| Description | integrin, alpha 11 |
| Notes | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008] |
| Ariadne Ontology | Focal junction assembly |
|---|---|
| ITG |
| GO Molecular Function | collagen binding |
|---|
| GO Cellular Component | membrane |
|---|---|
| integrin complex | |
| integral to membrane | |
| plasma membrane |
| GO Biological Process | cell adhesion |
|---|---|
| integrin-mediated signaling pathway | |
| cell-matrix adhesion | |
| substrate-dependent cell migration | |
| muscle organ development |
| Pathway | pancreatic cancer pathway |
|---|
| Group | Focal junction assembly |
|---|---|
| ITG | |
| cell adhesion | |
| integrin-mediated signaling pathway | |
| cell-matrix adhesion | |
| substrate-dependent cell migration | |
| muscle organ development | |
| collagen binding | |
| membrane | |
| integrin complex | |
| integral to membrane | |
| plasma membrane |
| MedScan ID | 22801 |
|---|
| Hugo ID | 6136 |
|---|
| Human chromosome position | 15q23 |
|---|
| LocusLink ID | 22801 |
|---|---|
| 319480 | |
| 315744 |
| Alias | HsT18964 |
|---|---|
| MSTP018 | |
| integrin alpha-11 | |
| 4732459H24Rik | |
| integrin a11 | |
| 4732459H24 | |
| ITGA11 | |
| integrin alpha 11 | |
| alpha xi integrin | |
| alpha 11 integrin | |
| Integrin alpha XI |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604789 |
|---|
| Unigene ID | Hs.436416 |
|---|---|
| Mm.34883 | |
| Rn.64478 |
| KEGG ID | hsa:22801 |
|---|---|
| mmu:319480 | |
| rno:315744 |
| Swiss-Prot Accession | B3KTN6 |
|---|---|
| Q9UKX5 | |
| Q7TQC3 | |
| Q8CE84 | |
| P61622 | |
| Q8WYI8 | |
| Q9UKQ1 |
| GO ID | 0005518 |
|---|---|
| 0007155 | |
| 0007160 | |
| 0007229 | |
| 0007517 | |
| 0008305 | |
| 0005886 | |
| 0006929 | |
| 0016021 | |
| 0016020 |
| Swiss-Prot ID | ITA11_HUMAN |
|---|
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00215613 |
|---|
| Mouse chromosome position | 9 |
|---|
| Rat chromosome position | 8q24 |
|---|
| Homologene ID | 8151 |
|---|
| MGI ID | 2442114 |
|---|
| RGD ID | 1311711 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|