| URN | urn:agi-llid:55193 |
|---|---|
| Total Entities | 0 |
| Connectivity | 49 |
| Name | Pbrm1 |
| Description | polybromo 1 |
| Notes | This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012] |
| Ariadne Ontology | Chromatin remodeling |
|---|
| GO Molecular Function | chromatin binding |
|---|---|
| DNA binding |
| GO Cellular Component | nuclear chromosome |
|---|---|
| kinetochore | |
| nucleus |
| GO Biological Process | mitosis |
|---|---|
| positive regulation of transcription, DNA-dependent | |
| regulation of transcription, DNA-dependent | |
| negative regulation of cell proliferation | |
| cardiac vascular smooth muscle cell development | |
| vasculogenesis involved in coronary vascular morphogenesis | |
| epicardium-derived cardiac endothelial cell differentiation | |
| transcription, DNA-dependent | |
| chromatin modification | |
| chromatin remodeling | |
| placenta development | |
| heart development | |
| heart morphogenesis | |
| blood vessel remodeling |
| Pathway | SWI/SNF BRG1/PBAF Chromatin Remodeling |
|---|---|
| pancreatic cancer pathway |
| Group | Chromatin remodeling |
|---|---|
| mitosis | |
| positive regulation of transcription, DNA-dependent | |
| regulation of transcription, DNA-dependent | |
| negative regulation of cell proliferation | |
| cardiac vascular smooth muscle cell development | |
| vasculogenesis involved in coronary vascular morphogenesis | |
| epicardium-derived cardiac endothelial cell differentiation | |
| transcription, DNA-dependent | |
| chromatin modification | |
| chromatin remodeling | |
| placenta development | |
| heart development | |
| heart morphogenesis | |
| blood vessel remodeling | |
| chromatin binding | |
| DNA binding | |
| nuclear chromosome | |
| kinetochore | |
| nucleus |
| MedScan ID | 55193 |
|---|
| Hugo ID | 30064 |
|---|
| Human chromosome position | 3p21 |
|---|
| LocusLink ID | 55193 |
|---|---|
| 66923 | |
| 306254 |
| Alias | PB1 |
|---|---|
| BAF180 | |
| protein polybromo-1 | |
| polybromo-1D | |
| BRG1-associated factor 180 | |
| AI507524 | |
| 2610016F04Rik | |
| 2310032M22Rik | |
| RGD1565549 | |
| polybromo 1 | |
| OTTHUMP00000202153 | |
| OTTHUMP00000202163 | |
| OTTMUSP00000028229 | |
| OTTMUSP00000028231 | |
| OTTMUSP00000028232 | |
| OTTMUSP00000028234 | |
| OTTMUSP00000028237 | |
| OTTMUSP00000028239 | |
| PBRM1 | |
| polybromo I | |
| OTTHUMP00000202151 | |
| OTTMUSP00000028236 | |
| OTTMUSP00000028240 | |
| BRG1/brm-associated factor 180 | |
| OTTHUMP00000202150 | |
| BRG1/Brahma-associated factor 180 | |
| OTTMUSP00000028238 | |
| MGC156155 | |
| Brahma-associated factor 180 | |
| MGC156156 | |
| brm-associated factor 180 | |
| hPB1 | |
| FLJ11064 | |
| FLJ10645 | |
| 2610016F04 | |
| OTTHUMP00000202149 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 606083 |
|---|
| Unigene ID | Hs.189920 |
|---|---|
| Hs.476320 | |
| Mm.27913 |
| KEGG ID | hsa:55193 |
|---|---|
| mmu:66923 | |
| rno:306254 |
| Swiss-Prot Accession | Q86U86 |
|---|---|
| F8VQD1 | |
| Q8BSQ9 | |
| A1L381 | |
| A1L382 | |
| A4FUJ7 | |
| Q1RMD1 | |
| Q1RMD2 | |
| Q96MS2 | |
| Q9H2T3 | |
| Q9H2T4 | |
| Q9H2T5 | |
| Q9H301 | |
| Q9H314 |
| GO ID | 0003677 |
|---|---|
| 0003682 | |
| 0006338 | |
| 0007507 | |
| 0007067 | |
| 0008285 | |
| 0001890 | |
| 0006355 | |
| 0006351 | |
| 0000776 | |
| 0000228 | |
| 0001974 | |
| 0060948 | |
| 0016568 | |
| 0003349 | |
| 0003007 | |
| 0045893 | |
| 0060979 | |
| 0005634 |
| Swiss-Prot ID | PB1_HUMAN |
|---|
| Cell Localization | Nucleus |
|---|
| IPI ID | IPI00023097 |
|---|---|
| IPI00301041 | |
| IPI00334894 | |
| IPI00384176 | |
| IPI00398781 | |
| IPI00640304 | |
| IPI00873041 | |
| IPI00909142 | |
| IPI00910435 |
| Mouse chromosome position | 14 |
|---|
| Rat chromosome position | 16p16 |
|---|
| Homologene ID | 10044 |
|---|
| MGI ID | 1923998 |
|---|
| RGD ID | 1565549 |
|---|
| Primary Cell Localization | Nucleus |
|---|