Protein Itga9

URN urn:agi-llid:3677
Total Entities 0
Connectivity 72
Name Itga9
Description integrin, alpha 9
Notes This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]

Ariadne Ontology Focal junction assembly
ITG

GO Molecular Function collagen binding
laminin binding

GO Cellular Component membrane
integrin complex
basal plasma membrane
alpha9-beta1 integrin complex
integral to membrane
plasma membrane

GO Biological Process cell adhesion
integrin-mediated signaling pathway
neutrophil chemotaxis
axon guidance
wound healing

Pathway pancreatic cancer pathway

Group Focal junction assembly
ITG
cell adhesion
integrin-mediated signaling pathway
neutrophil chemotaxis
axon guidance
wound healing
collagen binding
laminin binding
membrane
integrin complex
basal plasma membrane
alpha9-beta1 integrin complex
integral to membrane
plasma membrane

MedScan ID 3677

Hugo ID 6145

Human chromosome position 3p21.3

GenBank ID NC_000003
NM_002207
NP_002198
NG_016166
NC_018914
AC_000135
AC092055
AC093415
AP006240
CH471055
EAW64501
AK026826
AK123884
BC030198
AAH30198
BX647350
D25303
BAA04984
L24158
AAA16099
Q13797
NC_000075
NM_133721
NP_598482
NM_001113514
NP_001106986
AC_000031
AC156800
AC159000
AC165257
CH466587
EDL09248
CT486004
CAX15643
AJ344342
CAC69080
AK011287
AK032822
AK083987
BAC39086
AK139690
BAE24106
AK153585
BB638856
BC049939
AAH49939
BC150824
AAI50825
CF913701
CN698186
NC_005107
XM_001061864
XP_001061864
AC_000076
XM_002727107
XP_002727153
CA512590
CF109211
CK359386

LocusLink ID 3677
3680
104099
685004

Alias RLC
ITGA4L
ALPHA-RLC
integrin alpha-9
integrin alpha-RLC
(alpha)9
AI461869
D130073C02
D9Ertd428e
2610002H11Rik
6720458D17Rik
integrin alpha 9
Itga9l
integrin, alpha 9
DNA segment, Chr 9, ERATO Doi 428, expressed
LOC687154
LOC207691
ITGA9
integrin, alpha 4-like
integrin alpha 9 subunit
integin, alpha 9
6720458D17
alpha 9 integrin
2610002H11
alpha rlc integrin

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 603963

Unigene ID Hs.113157
Mm.335520
Rn.38697

KEGG ID hsa:3680
mmu:104099
rno:685004

Swiss-Prot Accession Q13797
Q8N6H6
E9QAP0
Q3UT74
B8JK39
Q14638

GO ID 0005518
0043236
0007411
0007155
0007229
0030593
0042060
0034679
0009925
0008305
0005886
0016021
0016020

PIR ID I58409

Swiss-Prot ID ITA9_HUMAN

Cell Localization Membrane
Plasma membrane

IPI ID IPI00015181

Mouse chromosome position 9 67.0 cM

Rat chromosome position 8q32

Homologene ID 1664

MGI ID 104756

RGD ID 1311191

Primary Cell Localization Plasma membrane