| URN | urn:agi-llid:1634 |
|---|---|
| Total Entities | 0 |
| Connectivity | 1111 |
| Name | DCN |
| Description | decorin |
| Notes | binds the N-terminal region of collagen VI; may play a role in extracellular matrix assembly [RGD] |
| GO Molecular Function | extracellular matrix binding |
|---|---|
| protein N-terminus binding | |
| collagen binding | |
| glycosaminoglycan binding |
| GO Cellular Component | extracellular matrix |
|---|---|
| extracellular region | |
| Golgi lumen | |
| lysosomal lumen | |
| proteinaceous extracellular matrix | |
| extracellular space | |
| collagen type VI |
| GO Biological Process | small molecule metabolic process |
|---|---|
| dermatan sulfate biosynthetic process | |
| chondroitin sulfate biosynthetic process | |
| chondroitin sulfate catabolic process | |
| chondroitin sulfate metabolic process | |
| peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan | |
| kidney development | |
| organ morphogenesis | |
| placenta development | |
| skeletal muscle tissue development | |
| aging | |
| extracellular matrix organization | |
| response to lipopolysaccharide | |
| wound healing | |
| response to mechanical stimulus | |
| carbohydrate metabolic process | |
| glycosaminoglycan metabolic process |
| Pathway | Proteins Involved in Pathogenesis of Atherosclerosis |
|---|---|
| Proteins Involved in Pathogenesis of Pulmonary Hypertension | |
| Proteins Involved in Pathogenesis of Glioma | |
| TGFB3-TGFBR2 Expression Targets | |
| TGFB1-TGFBR2 Expression Targets | |
| GH1-GHR/NF-kB/ELK-SRF/MYC Expression Targets | |
| GH1-GHR/STAT Expression Targets | |
| F2 -> AP-1/CREB/ELK-SRF/SP1 Expression Targets | |
| F2 -> STAT1/NF-kB Expression Targets | |
| Serotonin/Gq Expression Targets | |
| PDGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGF/STAT Expression Targets | |
| IL1B Expression Targets | |
| transforming growth factor-beta Smad dependent signaling pathway | |
| transforming growth factor-beta Smad dependent signaling pathway | |
| altered transforming growth factor-beta Smad dependent signaling pathway | |
| transforming growth factor-beta Smad dependent signaling pathway |
| Group | Extracellular matrix polymerization |
|---|---|
| small molecule metabolic process | |
| dermatan sulfate biosynthetic process | |
| chondroitin sulfate biosynthetic process | |
| chondroitin sulfate catabolic process | |
| chondroitin sulfate metabolic process | |
| peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan | |
| kidney development | |
| organ morphogenesis | |
| placenta development | |
| skeletal muscle tissue development | |
| aging | |
| extracellular matrix organization | |
| response to lipopolysaccharide | |
| wound healing | |
| response to mechanical stimulus | |
| carbohydrate metabolic process | |
| glycosaminoglycan metabolic process | |
| extracellular matrix binding | |
| protein N-terminus binding | |
| collagen binding | |
| glycosaminoglycan binding | |
| extracellular matrix | |
| extracellular region | |
| Golgi lumen | |
| lysosomal lumen | |
| proteinaceous extracellular matrix | |
| extracellular space | |
| collagen type VI | |
| Secreted proteins | |
| Biofluids assayable substances |
| LocusLink ID | 1634 |
|---|---|
| 13179 | |
| 29139 |
| Cell Localization | Extracellular |
|---|---|
| Secreted | |
| Extracellular space | |
| Extracellular matrix |
| GO ID | 0005518 |
|---|---|
| 0050840 | |
| 0005539 | |
| 0047485 | |
| 0007568 | |
| 0005975 | |
| 0030206 | |
| 0030207 | |
| 0030204 | |
| 0030208 | |
| 0030198 | |
| 0030203 | |
| 0001822 | |
| 0009887 | |
| 0019800 | |
| 0001890 | |
| 0032496 | |
| 0009612 | |
| 0007519 | |
| 0044281 | |
| 0042060 | |
| 0005796 | |
| 0005589 | |
| 0031012 | |
| 0005576 | |
| 0005615 | |
| 0043202 | |
| 0005578 | |
| 0005515 |
| Alias | CSCD |
|---|---|
| PG40 | |
| PGII | |
| PGS2 | |
| DSPG2 | |
| SLRR1B | |
| decorin | |
| PG-S2 | |
| bone proteoglycan II | |
| decorin proteoglycan | |
| proteoglycan core protein | |
| small leucine-rich protein 1B | |
| dermatan sulphate proteoglycans II | |
| DC | |
| mDcn | |
| DSPG | |
| dermatan sulfate proteoglycan-II (decorin) | |
| MGC94682 | |
| Dcn | |
| decorins | |
| dermatan sulfate proteoglycan-ii | |
| Bone proteoglycan II precursor |
| Mouse chromosome position | 10 50.27 cM |
|---|---|
| 10 55.0 cM |
| OMIM ID | 125255 |
|---|---|
| 610048 |
| Rat chromosome position | 7q13 |
|---|
| Hugo ID | 2705 |
|---|
| Human chromosome position | 12q21.33 |
|---|
| Swiss-Prot Accession | P07585 |
|---|---|
| Q6FH10 | |
| P28654 | |
| Q3UKR1 | |
| Q01129 | |
| Q9P0Z0 | |
| Q9P0Z1 | |
| Q9Y5N8 | |
| Q9Y5N9 |
| PIR ID | S29145 |
|---|---|
| A45016 | |
| B28457 | |
| A55454 |
| Unigene ID | Hs.156316 |
|---|---|
| Mm.56769 | |
| Rn.106103 | |
| Hs.706840 | |
| Hs.642609 |
| KEGG ID | hsa:1634 |
|---|---|
| mmu:13179 | |
| rno:29139 |
| Swiss-Prot ID | PGS2_RAT |
|---|---|
| PGS2_HUMAN | |
| PGS2_MOUSE |
| Ensembl ID | ENSG00000011465 |
|---|---|
| ENSP00000052754 | |
| ENST00000052754 | |
| ENSP00000376862 | |
| ENST00000393155 | |
| ENSP00000401021 | |
| ENST00000425043 | |
| ENSMUSG00000019929 | |
| ENSMUSP00000100924 | |
| ENSMUST00000105287 | |
| ENSMUSP00000131431 | |
| ENSMUST00000163448 | |
| ENSRNOG00000004554 | |
| ENSRNOP00000006070 | |
| ENSRNOT00000006070 |
| Homologene ID | 22430 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 94872 |
|---|
| RGD ID | 61895 |
|---|
| MedScan ID | 1634 |
|---|