| URN | urn:agi-Regulation:inout-urn:agi-llid:2:out-urn:agi-llid:7040::negative |
|---|---|
| References | 3 |
| Connectivity | 2 |
| Effect | negative |
| TextRef | info:pmid/14678766#abs:6 |
|---|---|
| MedLine Reference | 14678766:5 |
| Sentence | Interestingly, plasma alpha(2)M from two DD patients showed markedly increased TGF-beta1 binding. |
| CellLineName | DD |
| TextRef | info:pmid/15226301#abs:8 |
|---|---|
| MedLine Reference | 15226301:7 |
| Sentence | Cell surface annexin VI is also capable of mediating internalization and degradation of cell surface-bound (125)I-TGF-beta(1) and (125)I-alpha(2)M(*) at pH 6 and of forming ternary complexes with (125)I-alpha(2)M(*) and LRP-1 at neutral pH as demonstrated by co-immunoprecipitation. |
| Organism | Mus musculus |
| TextRef | info:pmid/8798779#cont:213 |
|---|---|
| MedLine Reference | 8798779:10212 |
| Sentence | Murine alpha 2 M, but not MUG, inhibits TGF-eta binding to its cellular receptors and the biological response of FBHE cells to TGF-eta. |
| Organism | Mus musculus |
| Journal | J. Biol. Chem |
| Journal Reference | v271 i40 p24982 |
| Journal Link | http://www.jbc.org/cgi/content/full/271/40/24982 |