| URN | urn:agi-llid:54894 |
|---|---|
| Connectivity | 2 |
| Name | Rnf43 |
| Description | ring finger protein 43 |
| Notes | RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM] |
| Pathway | Wnt signaling, canonical pathway |
|---|---|
| altered Wnt signaling, canonical pathway |
| GO Molecular Function | ligase activity |
|---|---|
| metal ion binding | |
| zinc ion binding |
| GO Cellular Component | membrane |
|---|---|
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| nuclear envelope | |
| nucleus | |
| integral to membrane |
| GO Biological Process | modification-dependent protein catabolic process |
|---|
| Group | modification-dependent protein catabolic process |
|---|---|
| ligase activity | |
| metal ion binding | |
| zinc ion binding | |
| membrane | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| nuclear envelope | |
| nucleus | |
| integral to membrane |
| MedScan ID | 54894 |
|---|
| Hugo ID | 18505 |
|---|
| Human chromosome position | 17q22 |
|---|
| LocusLink ID | 54894 |
|---|---|
| 207742 | |
| 303412 |
| Alias | URCC |
|---|---|
| RNF124 | |
| FLJ20315 | |
| FLJ77466 | |
| FLJ99338 | |
| MGC125630 | |
| DKFZp781H0392 | |
| DKFZp781H02126 | |
| RING finger protein 43 | |
| 4732452J19Rik | |
| RP23-449P23.1 | |
| RGD1305204 | |
| 4732452J19 | |
| LOC192957 | |
| RNF43 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 612482 |
|---|
| Mouse chromosome position | 11 |
|---|
| GO ID | 0016874 |
|---|---|
| 0046872 | |
| 0008270 | |
| 0005783 | |
| 0005789 | |
| 0016021 | |
| 0016020 | |
| 0005635 | |
| 0005634 | |
| 0019941 |
| Rat chromosome position | 10q26 |
|---|
| Swiss-Prot Accession | Q68DV7 |
|---|---|
| A3KMI3 | |
| Q5NCP0 | |
| Q99KA9 | |
| A8K4R2 | |
| B7Z443 | |
| B7Z5D5 | |
| B7Z5J5 | |
| Q65ZA4 | |
| Q6AI04 | |
| Q9NXD0 | |
| B2KGH3 | |
| Q6DI76 | |
| Q8BME0 | |
| Q8C191 | |
| Q8K0X4 |
| Unigene ID | Hs.584916 |
|---|---|
| Mm.440230 | |
| Rn.214174 |
| KEGG ID | hsa:54894 |
|---|---|
| mmu:207742 | |
| rno:303412 |
| Swiss-Prot ID | RNF43_HUMAN |
|---|---|
| RNF43_MOUSE | |
| A3KMI3_MOUSE | |
| B2KGH3_MOUSE |
| Cell Localization | Endoplasmic reticulum membrane |
|---|---|
| Nucleus envelope |
| IPI ID | IPI00744070 |
|---|---|
| IPI00930185 | |
| IPI00930238 | |
| IPI00930434 | |
| IPI00272698 | |
| IPI00626683 | |
| IPI00875921 | |
| IPI00223012 | |
| IPI00370697 |
| Homologene ID | 37742 |
|---|
| RGD ID | 1305204 |
|---|
| MGI ID | 2442609 |
|---|