| URN | urn:agi-llid:11197 |
|---|---|
| Connectivity | 45 |
| Name | Wif1 |
| Description | Wnt inhibitory factor 1 |
| Notes | human homolog has decreased mRNA expression in some prostate cancers and other cancers; may act as a secreted inhibitor of the Wnt signaling pathway [RGD] |
| Pathway | canonical Wnt signaling pathway |
|---|---|
| altered canonical Wnt signaling pathway | |
| canonical Wnt signaling pathway | |
| altered canonical Wnt signaling pathway | |
| Wnt signaling, canonical pathway | |
| altered Wnt signaling, canonical pathway |
| GO Molecular Function | Wnt-protein binding |
|---|---|
| protein tyrosine kinase activity |
| GO Cellular Component | extracellular region |
|---|
| GO Biological Process | multicellular organismal development |
|---|---|
| signal transduction | |
| negative regulation of Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway |
| Group | extracellular region |
|---|---|
| multicellular organismal development | |
| signal transduction | |
| negative regulation of Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway | |
| Wnt-protein binding | |
| protein tyrosine kinase activity |
| MedScan ID | 11197 |
|---|
| Hugo ID | 18081 |
|---|
| Human chromosome position | 12q14.3 |
|---|
| LocusLink ID | 11197 |
|---|---|
| 24117 | |
| 114557 |
| Alias | WIF-1 |
|---|---|
| UNQ191/PRO217 | |
| wnt inhibitory factor 1 | |
| AW107799 | |
| WIF I | |
| WIF1 | |
| WNT inhibitory factor I |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 605186 |
|---|
| Mouse chromosome position | 10 |
|---|---|
| 10 D2 |
| GO ID | 0004713 |
|---|---|
| 0016055 | |
| 0007275 | |
| 0007165 | |
| 0005576 | |
| 0017147 | |
| 0030178 | |
| 0003674 | |
| 0008150 | |
| 0005575 | |
| 0007267 | |
| 0005615 | |
| 0016021 | |
| 0016020 |
| Rat chromosome position | 7q22 |
|---|
| Swiss-Prot Accession | Q9Y5W5 |
|---|---|
| Q3TYU1 | |
| Q9WUA1 | |
| Q99KR2 | |
| Q6IN38 | |
| Q6UXI1 | |
| Q8WVG4 | |
| Q924Y6 |
| PIR ID | A59180 |
|---|
| Unigene ID | Hs.284122 |
|---|---|
| Mm.32831 | |
| Rn.74256 |
| KEGG ID | hsa:11197 |
|---|---|
| mmu:24117 | |
| rno:114557 |
| Swiss-Prot ID | WIF1_MOUSE |
|---|---|
| WIF1_HUMAN | |
| WIF1_RAT | |
| Q3TYU1_MOUSE |
| Cell Localization | Secreted |
|---|---|
| Extracellular |
| IPI ID | IPI00124441 |
|---|---|
| IPI00001863 | |
| IPI00205190 | |
| IPI00554094 | |
| IPI00462278 |
| Homologene ID | 31430 |
|---|
| RGD ID | 619774 |
|---|
| MGI ID | 1344332 |
|---|