| URN | urn:agi-llid:1452 |
|---|---|
| Total Entities | 0 |
| Connectivity | 174 |
| Name | Csnk1a1 |
| Description | casein kinase 1, alpha 1 |
| Notes | splice variant isoforms CKI alpha and CKI alpha L both have casein kinase I activity but display differences in substrate kinetics [RGD] |
| Ariadne Ontology | Secreted proteins |
|---|
| GO Molecular Function | glycoprotein binding |
|---|---|
| phosphoprotein binding | |
| nucleotide binding | |
| ATP binding | |
| peptide binding | |
| magnesium ion binding | |
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity |
| GO Cellular Component | mRNA cleavage and polyadenylation specificity factor complex |
|---|---|
| nuclear speck | |
| chromosome, centromeric region | |
| kinetochore | |
| condensed chromosome kinetochore | |
| microtubule organizing center | |
| centrosome | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cytosol | |
| chromosome | |
| cytoskeleton | |
| nucleus |
| GO Biological Process | cell division |
|---|---|
| cell cycle | |
| mitosis | |
| signal transduction | |
| cell surface receptor signaling pathway | |
| Wnt receptor signaling pathway | |
| cell morphogenesis | |
| protein phosphorylation | |
| phosphorylation |
| Pathway | Wnt signaling, canonical pathway |
|---|---|
| altered Wnt signaling, canonical pathway | |
| canonical Wnt signaling pathway | |
| Wnt signaling, canonical pathway | |
| altered Wnt signaling, canonical pathway |
| Group | cell division |
|---|---|
| cell cycle | |
| mitosis | |
| signal transduction | |
| cell surface receptor signaling pathway | |
| Wnt receptor signaling pathway | |
| cell morphogenesis | |
| protein phosphorylation | |
| phosphorylation | |
| glycoprotein binding | |
| phosphoprotein binding | |
| nucleotide binding | |
| ATP binding | |
| peptide binding | |
| magnesium ion binding | |
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| mRNA cleavage and polyadenylation specificity factor complex | |
| nuclear speck | |
| chromosome, centromeric region | |
| kinetochore | |
| condensed chromosome kinetochore | |
| microtubule organizing center | |
| centrosome | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cytosol | |
| chromosome | |
| cytoskeleton | |
| nucleus | |
| Secreted proteins |
| MedScan ID | 1452 |
|---|
| Hugo ID | 2451 |
|---|
| Human chromosome position | 5q32 |
|---|
| LocusLink ID | 1452 |
|---|---|
| 93687 | |
| 113927 |
| Alias | CK1 |
|---|---|
| CK1a | |
| CKIa | |
| HLCDGP1 | |
| PRO2975 | |
| CK1alpha | |
| CKIalpha | |
| casein kinase I isoform alpha | |
| CKI-alpha | |
| clock regulator kinase | |
| down-regulated in lung cancer | |
| Csnk1a | |
| 2610208K14Rik | |
| 4632404G05Rik | |
| 5430427P18Rik | |
| casein kinase I-alpha | |
| Csnk1a I | |
| OTTHUMP00000224000 | |
| MGC30571 | |
| MGC29354 | |
| MGC156603 | |
| LOC153687 | |
| Csnk1a1 | |
| 4632404G05 | |
| HLCDGP I | |
| 5430427P18 | |
| casein kinase 1, alpha | |
| casein kinase 1, alpha 1 | |
| Casein kinase I, alpha isoform | |
| CK1 alpha | |
| 2610208K14 | |
| RIKEN cDNA 5430427P18 gene | |
| RIKEN cDNA 2610208K14 gene | |
| RIKEN cDNA 4632404G05 gene | |
| CK I | |
| CK 1 | |
| CK-1 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600505 |
|---|
| Unigene ID | Hs.529862 |
|---|---|
| Hs.712555 | |
| Mm.26908 | |
| Mm.472989 | |
| Mm.473442 | |
| Rn.23810 | |
| Hs.699188 | |
| Mm.391711 | |
| Mm.393114 |
| KEGG ID | hsa:1452 |
|---|---|
| mmu:93687 | |
| rno:113927 |
| Swiss-Prot Accession | P48729 |
|---|---|
| Q6PJ06 | |
| Q05DL3 | |
| Q6PJ87 | |
| Q8BK63 | |
| P97633 | |
| P97634 | |
| D3DQG0 | |
| D3DQG1 | |
| Q4JJA0 | |
| Q5U046 | |
| Q5U047 | |
| Q6FGA2 | |
| Q96HD2 | |
| Q9UDK3 | |
| Q71TU5 | |
| Q8WXF2 | |
| Q9P137 | |
| Q3TVX1 | |
| Q3U772 | |
| Q3U844 |
| EC Number | 2.7.11.1 |
|---|---|
| 2.7.1.- |
| GO ID | 0005524 |
|---|---|
| 0004672 | |
| 0004674 | |
| 0016055 | |
| 0051301 | |
| 0000902 | |
| 0007166 | |
| 0007067 | |
| 0006468 | |
| 0007165 | |
| 0005813 | |
| 0000777 | |
| 0005829 | |
| 0005847 | |
| 0016607 | |
| 0030529 | |
| 0001948 | |
| 0016301 | |
| 0000287 | |
| 0000166 | |
| 0042277 | |
| 0051219 | |
| 0016740 | |
| 0016772 | |
| 0007049 | |
| 0016310 | |
| 0005694 | |
| 0000775 | |
| 0005737 | |
| 0005856 | |
| 0000776 | |
| 0005634 | |
| 0005815 | |
| 0005625 | |
| 0005515 | |
| 0005575 | |
| 0008150 | |
| 0004681 | |
| 0004680 | |
| 0000004 | |
| 0008372 |
| PIR ID | A57011 |
|---|---|
| S46254 |
| Swiss-Prot ID | KC1A_RAT |
|---|---|
| KC1A_HUMAN | |
| D3DQG1_HUMAN | |
| Q05DL3_HUMAN | |
| Q6PJ06_HUMAN | |
| D3DQG0_HUMAN | |
| Q6PJ87_MOUSE |
| Cell Localization | Cytoplasm |
|---|---|
| cytoskeleton | |
| centrosome | |
| Chromosome | |
| centromere | |
| kinetochore | |
| Nucleus speckle |
| IPI ID | IPI00206466 |
|---|---|
| IPI00231832 | |
| IPI00183400 | |
| IPI00448798 | |
| IPI00467055 | |
| IPI00292086 | |
| IPI00330729 |
| Mouse chromosome position | 18 |
|---|---|
| 18 D3 |
| Rat chromosome position | 18q12.1 |
|---|
| Homologene ID | 111694 |
|---|---|
| 37546 |
| MGI ID | 1934950 |
|---|
| RGD ID | 71098 |
|---|