| URN | urn:agi-llid:64116 |
|---|---|
| Total Entities | 0 |
| Connectivity | 100 |
| Name | Slc39a8 |
| Description | solute carrier family 39 (zinc transporter), member 8 |
| Notes | This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008] |
| GO Molecular Function | metal ion transmembrane transporter activity |
|---|
| GO Cellular Component | membrane |
|---|---|
| integral component of membrane | |
| organelle membrane | |
| plasma membrane |
| GO Biological Process | transmembrane transport |
|---|---|
| ion transport | |
| metal ion transport | |
| zinc ion transport | |
| transport |
| Pathway | iron homeostasis pathway |
|---|
| Group | Me++ homeostasis |
|---|---|
| transmembrane transport | |
| metal ion transmembrane transporter activity | |
| ion transport | |
| metal ion transport | |
| zinc ion transport | |
| transport | |
| membrane | |
| integral component of membrane | |
| organelle membrane | |
| plasma membrane |
| LocusLink ID | 64116 |
|---|---|
| 67547 | |
| 295455 |
| Cell Localization | Plasma membrane |
|---|---|
| Membrane |
| GO ID | 0046873 |
|---|---|
| 0055085 | |
| 0006829 | |
| 0016021 | |
| 0031090 | |
| 0005886 | |
| 0006811 | |
| 0030001 | |
| 0006810 | |
| 0016020 |
| Alias | ZIP8 |
|---|---|
| PP3105 | |
| BIGM103 | |
| LZT-Hs6 | |
| zinc transporter ZIP8 | |
| ZIP-8 | |
| Zrt- and Irt-like protein 8 | |
| solute carrier family 39 member 8 | |
| LIV-1 subfamily of ZIP zinc transporter 6 | |
| BCG induced integral membrane protein BIGM103 | |
| solute carrier family 39 (metal ion transporter), member 8 | |
| BCG-induced integral membrane protein in monocyte clone 103 protein | |
| AA986696 | |
| 4933419D20Rik | |
| solute carrier family 39 (zinc transporter), member VIII | |
| SLC39A8 | |
| solute carrier family 39 (metal ion transporter), member VIII | |
| solute carrier family 39 (zinc transporter), member 8 | |
| up-regulated by BCG-CWS | |
| BCG-induced gene in monocytes, clone 103 | |
| OTTMUSP00000029072 | |
| BCG-induced gene in monocytes, clone | |
| 4933419D20 | |
| MGC108852 | |
| OTTMUSP00000029071 |
| Mouse chromosome position | 3 63.04 cM |
|---|
| OMIM ID | 608732 |
|---|
| Rat chromosome position | 2q43 |
|---|
| Hugo ID | 20862 |
|---|
| Human chromosome position | 4q22-q24 |
|---|
| Swiss-Prot Accession | Q9C0K1 |
|---|---|
| Q91W10 | |
| Q5FVQ0 | |
| B4E2H3 | |
| Q96SM9 | |
| Q9BVC0 | |
| Q9NSA4 | |
| Q8BTQ3 | |
| Q8BUD6 | |
| Q9D426 | |
| Q9D5V4 |
| Unigene ID | Hs.288034 |
|---|---|
| Mm.30239 | |
| Mm.491277 | |
| Rn.28321 |
| KEGG ID | hsa:64116 |
|---|---|
| mmu:67547 | |
| rno:295455 |
| Swiss-Prot ID | S39A8_HUMAN |
|---|---|
| S39A8_RAT | |
| S39A8_MOUSE |
| Ensembl ID | ENSG00000138821 |
|---|---|
| ENSP00000349174 | |
| ENST00000356736 | |
| ENSP00000394548 | |
| ENST00000424970 | |
| ENSP00000378310 | |
| ENST00000394833 | |
| ENSMUSG00000053897 | |
| ENSMUSP00000136634 | |
| ENSMUST00000180196 | |
| ENSMUSP00000128245 | |
| ENSMUST00000167390 | |
| ENSMUSP00000080640 | |
| ENSMUST00000081978 | |
| ENSMUSP00000029810 | |
| ENSMUST00000029810 | |
| ENSRNOG00000012508 | |
| ENSRNOP00000030977 | |
| ENSRNOT00000033413 |
| Homologene ID | 11155 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1914797 |
|---|
| RGD ID | 1308236 |
|---|
| MedScan ID | 64116 |
|---|