| URN | urn:agi-llid:30061 |
|---|---|
| Total Entities | 0 |
| Connectivity | 397 |
| Name | Slc40a1 |
| Description | solute carrier family 40 (iron-regulated transporter), member 1 |
| Notes | The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4). [provided by RefSeq, Jul 2008] |
| GO Molecular Function | iron ion transmembrane transporter activity |
|---|
| GO Cellular Component | membrane |
|---|---|
| integral component of membrane | |
| integral component of plasma membrane | |
| plasma membrane | |
| cytoplasm | |
| multivesicular body | |
| synaptic vesicle |
| GO Biological Process | lymphocyte homeostasis |
|---|---|
| spleen development | |
| spleen trabecula formation | |
| multicellular organismal iron ion homeostasis | |
| transmembrane transport | |
| iron ion transmembrane transport | |
| cellular iron ion homeostasis | |
| apoptotic process | |
| negative regulation of apoptotic process | |
| ion transport | |
| iron ion transport | |
| anatomical structure morphogenesis | |
| endothelium development | |
| transport | |
| iron ion homeostasis |
| Pathway | iron homeostasis pathway |
|---|
| Group | Me++ homeostasis |
|---|---|
| lymphocyte homeostasis | |
| spleen development | |
| spleen trabecula formation | |
| multicellular organismal iron ion homeostasis | |
| transmembrane transport | |
| iron ion transmembrane transport | |
| iron ion transmembrane transporter activity | |
| cellular iron ion homeostasis | |
| apoptotic process | |
| negative regulation of apoptotic process | |
| ion transport | |
| iron ion transport | |
| anatomical structure morphogenesis | |
| endothelium development | |
| transport | |
| iron ion homeostasis | |
| membrane | |
| integral component of membrane | |
| integral component of plasma membrane | |
| plasma membrane | |
| cytoplasm | |
| multivesicular body | |
| synaptic vesicle | |
| Secreted proteins | |
| Biofluids assayable substances |
| LocusLink ID | 30061 |
|---|---|
| 53945 | |
| 170840 |
| Cell Localization | Plasma membrane |
|---|---|
| Cell membrane |
| GO ID | 0005381 |
|---|---|
| 0009653 | |
| 0006915 | |
| 0006879 | |
| 0003158 | |
| 0034755 | |
| 0002260 | |
| 0060586 | |
| 0060345 | |
| 0055085 | |
| 0005737 | |
| 0016021 | |
| 0005887 | |
| 0005771 | |
| 0005886 | |
| 0008021 | |
| 0006811 | |
| 0055072 | |
| 0006826 | |
| 0043066 | |
| 0048536 | |
| 0006810 | |
| 0016020 |
| Alias | FPN1 |
|---|---|
| HFE4 | |
| MTP1 | |
| IREG1 | |
| MST079 | |
| MSTP079 | |
| SLC11A3 | |
| solute carrier family 40 member 1 | |
| iron regulated gene 1 | |
| putative ferroportin 1 variant IIIA | |
| putative ferroportin 1 variant IIIB | |
| solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3 | |
| MTP | |
| Ol5 | |
| Pcm | |
| Dusg | |
| Slc39a1 | |
| ferroportin 1 | |
| ferroportin-1 | |
| polycythaemia | |
| duodenal-specific | |
| SLC11A3 iron transporter | |
| metal transporter protein 1 | |
| iron-regulated transporter 1 | |
| metal transporting protein 1 | |
| solute carrier family 39 (iron-regulated transporter), member 1 | |
| CAR1 | |
| cell adhesion regulator | |
| Fpt1 | |
| MTP I | |
| OTTHUMP00000207310 | |
| SLC40A1 | |
| solute carrier family 40 (iron-regulated transporter), member 1 | |
| solute carrier family 40 (iron-regulated transporter), member I | |
| ferroportin | |
| iron regulated gene I | |
| LOC227053 | |
| ferroportin 1 variant iiib | |
| ferroportin 1, iron regulated gene 1 | |
| FPN I | |
| IREG I | |
| ferroportin I |
| Mouse chromosome position | 1 |
|---|
| OMIM ID | 604653 |
|---|---|
| 606069 |
| Rat chromosome position | 9q22 |
|---|
| Hugo ID | 10909 |
|---|
| Human chromosome position | 2q32 |
|---|
| Swiss-Prot Accession | Q9NP59 |
|---|---|
| Q9JHI9 | |
| G3V6H7 | |
| Q923U9 | |
| Q6FI62 | |
| Q7Z4F8 | |
| Q8IVB2 | |
| Q9NRL0 | |
| Q9Z1C9 | |
| Q3UHZ9 | |
| Q8BME5 | |
| Q8BUM5 | |
| Q9JIM9 | |
| Q9JKP4 |
| Unigene ID | Hs.643005 |
|---|---|
| Mm.28756 | |
| Rn.15324 |
| KEGG ID | hsa:30061 |
|---|---|
| mmu:53945 | |
| rno:170840 |
| Swiss-Prot ID | S40A1_HUMAN |
|---|---|
| S40A1_RAT | |
| S40A1_MOUSE |
| Ensembl ID | ENSG00000138449 |
|---|---|
| ENSP00000261024 | |
| ENST00000261024 | |
| ENSMUSG00000025993 | |
| ENSMUSP00000027137 | |
| ENSMUST00000027137 | |
| ENSRNOG00000003872 | |
| ENSRNOP00000005228 | |
| ENSRNOT00000005228 |
| Homologene ID | 40959 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1315204 |
|---|
| RGD ID | 620180 |
|---|
| MedScan ID | 30061 |
|---|