| URN | urn:agi-llid:8031 |
|---|---|
| Total Entities | 0 |
| Connectivity | 135 |
| Name | Ncoa4 |
| Description | nuclear receptor coactivator 4 |
| Notes | This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009] |
| GO Molecular Function | transcription coactivator activity |
|---|---|
| androgen receptor binding |
| GO Cellular Component | mitochondrion |
|---|---|
| nucleus |
| GO Biological Process | male gonad development |
|---|---|
| androgen receptor signaling pathway | |
| response to hormone | |
| positive regulation of transcription, DNA-templated | |
| transcription, DNA-templated |
| Pathway | Prostate Cancer Overview |
|---|---|
| Proteins Involved in Pathogenesis of Prostate Cancer | |
| iron homeostasis pathway |
| Group | male gonad development |
|---|---|
| androgen receptor signaling pathway | |
| response to hormone | |
| positive regulation of transcription, DNA-templated | |
| transcription coactivator activity | |
| transcription, DNA-templated | |
| androgen receptor binding | |
| mitochondrion | |
| nucleus |
| LocusLink ID | 8031 |
|---|---|
| 27057 | |
| 619385 |
| GO ID | 0050681 |
|---|---|
| 0003713 | |
| 0030521 | |
| 0008584 | |
| 0045893 | |
| 0009725 | |
| 0006351 | |
| 0005634 | |
| 0005739 |
| Alias | RFG |
|---|---|
| ELE1 | |
| PTC3 | |
| ARA70 | |
| RP11-481A12.4 | |
| nuclear receptor coactivator 4 | |
| NCoA-4 | |
| ret fused | |
| 70 kDa AR-activator | |
| RET-activating gene ELE1 | |
| 70 kDa androgen receptor coactivator | |
| androgen receptor-associated protein of 70 kDa | |
| ELE1alpha | |
| nuclear receptor coactivator IV | |
| OTTHUMP00000019601 | |
| OTTHUMP00000019602 | |
| OTTHUMP00000019603 | |
| RET-activating gene ELE I | |
| RIKEN cDNA 1110034E15 gene | |
| androgen receptor-associated protein 70 | |
| RFG/ELE1alpha/ARA70 | |
| RIKEN cDNA 4432406M01 gene | |
| 4432406M01Rik | |
| NCOA4 | |
| 4432406M01 | |
| 4432406M01Rik(2) | |
| AI227008 | |
| MGC72479 | |
| DKFZp762E1112 | |
| ELE I | |
| GNB:557270 | |
| 1110034E15 | |
| 1110034E15Rik |
| Mouse chromosome position | 14 |
|---|
| OMIM ID | 601984 |
|---|---|
| 188550 |
| Rat chromosome position | 16p16 |
|---|
| Hugo ID | 7671 |
|---|
| Human chromosome position | 10q11.2 |
|---|
| Swiss-Prot Accession | Q13772 |
|---|---|
| Q96E88 | |
| B2R5V0 | |
| B4DZ85 | |
| B4DF87 | |
| Q5U4H9 | |
| B1H215 | |
| A8K8W5 | |
| B4E260 | |
| E9PAV7 | |
| J3KQN8 | |
| Q14239 |
| PIR ID | S61532 |
|---|
| Unigene ID | Hs.643658 |
|---|---|
| Hs.709644 | |
| Mm.371598 | |
| Mm.477186 | |
| Rn.165968 | |
| Rn.198999 |
| KEGG ID | hsa:8031 |
|---|---|
| mmu:27057 | |
| rno:619385 |
| Swiss-Prot ID | NCOA4_HUMAN |
|---|
| Ensembl ID | ENSG00000138293 |
|---|---|
| ENSP00000395465 | |
| ENST00000452682 | |
| ENSP00000405146 | |
| ENST00000438493 | |
| ENSP00000390713 | |
| ENST00000443446 | |
| ENSP00000363200 | |
| ENST00000374087 | |
| ENSP00000344552 | |
| ENST00000344348 | |
| ENSMUSG00000056234 | |
| ENSMUSP00000126071 | |
| ENSMUST00000163336 | |
| ENSMUSP00000107625 | |
| ENSMUST00000111994 | |
| ENSRNOG00000019768 | |
| ENSRNOP00000026803 | |
| ENSRNOT00000026803 | |
| ENSRNOP00000061299 | |
| ENSRNOT00000066062 |
| Homologene ID | 38052 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1350932 |
|---|
| RGD ID | 1563014 |
|---|
| MedScan ID | 8031 |
|---|