| Hugo ID | 7029 |
|---|---|
| Name | Met |
| Description | met proto-oncogene |
| Notes | hepatocyte growth factor receptor; functions as a heterodimeric tyrosine kinase [RGD] |
| Owner | Public |
| URN | urn:agi-llid:4233 |
| Connectivity | 712 |
| Source | Curated |
|---|
| LocusLink ID | 4233 |
|---|---|
| 17295 | |
| 24553 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 164860 |
|---|---|
| 114550 | |
| 605074 |
| Alias | HGFR |
|---|---|
| RCCP2 | |
| met proto-oncogene | |
| Oncogene MET | |
| HGF | |
| Par4 | |
| c-Met | |
| HGF receptor | |
| pulmonary adenoma resistance 4 | |
| hepatocyte growth factor receptor |
| GO ID | 0005524 |
|---|---|
| 0005008 | |
| 0000166 | |
| 0005515 | |
| 0004713 | |
| 0004872 | |
| 0016740 | |
| 0008283 | |
| 0007275 | |
| 0006468 | |
| 0007165 | |
| 0009925 | |
| 0005887 | |
| 0016020 | |
| 0016301 | |
| 0004672 | |
| 0004674 | |
| 0000187 | |
| 0030534 | |
| 0007420 | |
| 0048012 | |
| 0007517 | |
| 0051450 | |
| 0046777 | |
| 0005615 | |
| 0016021 | |
| 0005624 | |
| 0001764 |
| Swiss-Prot Accession | P08581 |
|---|---|
| Q12875 | |
| Q14825 | |
| Q59EB3 | |
| Q9UDX7 | |
| Q9UEJ3 | |
| Q9UMU9 | |
| P16056 | |
| O35515 | |
| P97523 | |
| Q99MC5 |
| Unigene ID | Hs.132966 |
|---|---|
| Mm.86844 | |
| Rn.10617 |
| RGD ID | 3082 |
|---|
| MGI ID | 96969 |
|---|---|
| 1197520 |
| Cell Localization | Plasma membrane |
|---|
| Pathway | HGF |
|---|---|
| MET -> STAT1 signaling pathway | |
| MET -> STAT3 signaling pathway | |
| MET -> STAT5A signaling pathway | |
| MET -> STAT5B signaling pathway | |
| scatter factor-hepatocyte growth factor signaling pathway |
| Group | Kinases |
|---|---|
| notch_receptors | |
| development | |
| signal transduction | |
| hepatocyte growth factor receptor signaling pathway | |
| activation of MAPK activity | |
| neuron migration | |
| cell proliferation | |
| myoblast proliferation | |
| protein amino acid phosphorylation | |
| protein amino acid autophosphorylation | |
| brain development | |
| muscle development | |
| adult behavior | |
| membrane | |
| basal plasma membrane | |
| membrane fraction | |
| integral to membrane | |
| integral to plasma membrane | |
| extracellular space | |
| nucleotide binding | |
| protein binding | |
| ATP binding | |
| transferase activity | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| protein-tyrosine kinase activity | |
| hepatocyte growth factor receptor activity | |
| receptor activity |