| Hugo ID | 4893 |
|---|---|
| Name | Hgf |
| Description | hepatocyte growth factor |
| Notes | plays a role in positive regulation of cell proliferation; may promote entry into the cell cycle [RGD] |
| Owner | Public |
| URN | urn:agi-llid:3082 |
| Connectivity | 1633 |
| Source | Curated |
|---|
| LocusLink ID | 3082 |
|---|---|
| 15234 | |
| 24446 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 142409 |
|---|
| Alias | SF |
|---|---|
| HGFB | |
| HPTA | |
| F-TCF | |
| hepatocyte growth factor | |
| scatter factor | |
| hepatopoietin A | |
| lung fibroblast-derived mitogen | |
| fibroblast-derived tumor cytotoxic factor | |
| NK1 | |
| NK2 | |
| HGF/SF | |
| SF/HGF | |
| C230052L06Rik | |
| Hepatocyte growth factor (scatter factor) |
| GO ID | 0005509 |
|---|---|
| 0008083 | |
| 0004252 | |
| 0007596 | |
| 0007067 | |
| 0006508 | |
| 0008372 | |
| 0000187 | |
| 0006916 | |
| 0008283 | |
| 0000902 | |
| 0048012 | |
| 0051450 | |
| 0005171 | |
| 0006928 | |
| 0008284 |
| Swiss-Prot Accession | P14210 |
|---|---|
| Q59H59 | |
| O55027 | |
| Q08048 | |
| Q53WS5 | |
| P17945 |
| Unigene ID | Hs.396530 |
|---|---|
| Mm.267078 | |
| Rn.10468 |
| RGD ID | 2794 |
|---|
| MGI ID | 96079 |
|---|
| Cell Localization | Extracellular |
|---|
| Pathway | HGF |
|---|---|
| MET -> STAT1 signaling pathway | |
| MET -> STAT3 signaling pathway | |
| MET -> STAT5A signaling pathway | |
| MET -> STAT5B signaling pathway | |
| scatter factor-hepatocyte growth factor signaling pathway |
| Group | notch_ligands |
|---|---|
| hepatocyte growth factor receptor signaling pathway | |
| activation of MAPK activity | |
| cell motility | |
| cell proliferation | |
| mitosis | |
| anti-apoptosis | |
| cell morphogenesis | |
| myoblast proliferation | |
| positive regulation of cell proliferation | |
| proteolysis | |
| blood coagulation | |
| cellular_component | |
| calcium ion binding | |
| growth factor activity | |
| hepatocyte growth factor receptor binding | |
| serine-type endopeptidase activity |