Ariadne Genomics Inc. Hsd11b2 ---| Nr3c2 cortisol ---- Nr3c2 cortisone cortisol aldosterone aldosterone biosynthetic pathway steroid hormone biosynthetic pathway Nr3c2 target genes Hsd11b2 Nr3c2 ---> translocated Nr3c2 complex translocated Nr3c2 complex Nr3c2 aldosterone ---- Nr3c2 cortisol ---> cortisone Nr3c2 ---- Nr3c2 chaperones Nr3c2 corepressors ---- translocated Nr3c2 complex Nr3c2 coactivators ---- translocated Nr3c2 complex Nr3c2 coactivators --+> translocated Nr3c2 complex Nr3c2 corepressors ---| translocated Nr3c2 complex translocated Nr3c2 complex ---> Nr3c2 target genes Nr3c2 chaperones Nr3c2 corepressors Nr3c2 coactivators