Protein Camkk1

URN	urn:agi-llid:11121
Total Entities	0
Connectivity	50
Name	Camkk1
Description	calcium/calmodulin-dependent protein kinase kinase 1, alpha
Notes	The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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Ariadne Ontology	CAMKK

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GO Molecular Function	calmodulin binding
	nucleotide binding
	ATP binding
	transferase activity
	transferase activity, transferring phosphorus-containing groups
	kinase activity
	protein kinase activity
	protein serine-threonine kinase activity
	calmodulin-dependent protein kinase activity

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GO Cellular Component	cytoplasm
	cytosol
	nucleus

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GO Biological Process	synaptic transmission
	positive regulation of protein kinase activity
	activation of protein kinase activity
	protein phosphorylation
	phosphorylation

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Pathway	T-cell receptor -> CREBBP signaling
	EGFR/ERBB3 -> MEF/MYOD/NFATC/MYOG signaling
	NeuropeptideYR -> ATF/CREB signaling
	VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling
	VasopressinR2 -> MEF/MYOD/NFATC/MYOG signaling
	NPY Expression Targets
	HBEGF/MEF/MYOD Expression Target
	NRG1/MEF/MYOD Expression Targets
	TGFA/MEF/MYOD/NFATC Expression Targets
	AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
	AVP/Gs -> MEF/MYOD/NFATC/MYOG Expression Targets
	IL16/ATF/CREB/CREBBP Expression Target
	CD8/ATF/CREB/CREBBP Expression Targets
	CD80/ATF/CREB/CREBBP Expression Targets
	CD86/ATF/CREB/CREBBP Expression Targets
	CD72/CREB/CREBBP Expression Targets
	PDCD1/ATF/CREB/CREBBP Expression Targets
	TCR/CREB/CREBBP/ATF Expression Targets
	adenosine monophosphate-activated protein kinase (AMPK) signaling pathway

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Group	CAMKK
	synaptic transmission
	positive regulation of protein kinase activity
	activation of protein kinase activity
	protein phosphorylation
	phosphorylation
	calmodulin binding
	nucleotide binding
	ATP binding
	transferase activity
	transferase activity, transferring phosphorus-containing groups
	kinase activity
	protein kinase activity
	protein serine-threonine kinase activity
	calmodulin-dependent protein kinase activity
	cytoplasm
	cytosol
	nucleus

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MedScan ID	11121

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Hugo ID	1469

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Human chromosome position	17p13.2

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GenBank ID	NC_000017
	NM_032294
	NP_115670
	NM_172206
	NP_757343
	NM_172207
	NP_757344
	NC_018928
	AC_000149
	AC005940
	CH471108
	EAW90474
	EAW90475
	EAW90476
	AF370377
	AAQ15213
	AF425232
	AAN37386
	AF425301
	AAN37387
	AK128601
	AL136576
	CAB66511
	BC011401
	BC031647
	AAH31647
	BC043487
	AAH43487
	Q8N5S9
	DQ892421
	ABM83347
	DQ895635
	ABM86561
	NC_000077
	NM_018883
	NP_061371
	NT_166317
	AC_000033
	AF461702
	AAL67849
	AF461703
	AF461704
	AF461705
	AF461706
	AL670399
	CAI24784
	CAI24785
	CH466596
	EDL12707
	CU210938
	CAQ51966
	CAQ51967
	AF117384
	AAF08348
	AI846603
	AK144483
	BC017529
	AAH17529
	Q8VBY2
	NC_005109
	NM_031662
	NP_113850
	AC_000078
	CH473948
	EDM05132
	AB023658
	BAA75246
	L42810
	AAC42070
	S83194
	AAB46910
	P97756

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LocusLink ID	11121
	84254
	55984
	60341

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Alias	CAMKKA
	calcium/calmodulin-dependent protein kinase kinase 1
	caMKK 1
	caM-KK 1
	caM-KK alpha
	CAMKK alpha protein
	caM-kinase kinase 1
	caM-kinase IV kinase
	caM-kinase kinase alpha
	calcium/calmodulin-dependent protein kinase kinase alpha
	Camkk
	AI846603
	CaMKKalpha
	RP23-263M10.4
	caMKK alpha
	calcium calmodulin dependent protein kinase kinase alpha
	alpha CaMKK
	OTTHUMP00000115904
	Camkk1
	CAM-KKA
	CaM-KKalpha
	DKFZp761M0423
	OTTHUMP00000115903
	Camkk I
	OTTMUSP00000006419
	OTTMUSP00000006420
	MGC34095
	calcium/calmodulin-dependent kinase 1 alpha
	calcium/calmodulin-dependent protein kinase 1 alpha isoform a
	calcium/calmodulin-dependent protein kinase 1 alpha isoform b
	calcium/calmodulin-dependent protein kinase kinase 1, alpha

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Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus

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OMIM ID	611411

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Unigene ID	Hs.8417
	Mm.9998
	Rn.4851

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KEGG ID	hsa:84254
	mmu:55984
	rno:60341

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Swiss-Prot Accession	Q8N5S9
	B1AUD2
	Q8VBY2
	P97756
	Q64572
	Q794E3
	Q9BQH3
	Q9R054

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EC Number	2.7.11.17

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GO ID	0005524
	0005516
	0004683
	0032147
	0007268
	0005829
	0005634
	0016301
	0000166
	0004672
	0004674
	0016740
	0016772
	0016310
	0045860
	0006468
	0005737

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PIR ID	A57156

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Swiss-Prot ID	KKCC1_RAT
	KKCC1_HUMAN
	KKCC1_MOUSE

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Cell Localization	Cytoplasm
	Nucleus

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IPI ID	IPI00207573
	IPI00017083
	IPI00166909
	IPI00626535

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Mouse chromosome position	11

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Rat chromosome position	10q24

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Homologene ID	10327

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MGI ID	1891766

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RGD ID	62023

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Primary Cell Localization	Cytoplasm

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