| URN | urn:agi-llid:5837 |
|---|---|
| Connectivity | 57 |
| Name | Pygm |
| Description | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) |
| Notes | Glycogen phosphorylase (EC 2.4.1.1) catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate.[supplied by OMIM] |
| Pathway | glycogen degradation pathway |
|---|
| GO Molecular Function | nucleotide binding |
|---|---|
| drug binding | |
| transferase activity | |
| sugar binding | |
| pyridoxal phosphate binding | |
| protein homodimerization activity | |
| AMP binding | |
| transferase activity, transferring glycosyl groups | |
| phosphorylase activity | |
| glycogen phosphorylase activity |
| GO Cellular Component | soluble fraction |
|---|---|
| cytoplasm | |
| cytosol | |
| sarcoplasmic reticulum | |
| Z disc |
| GO Biological Process | glycogen metabolic process |
|---|---|
| glycogen catabolic process | |
| cellular calcium ion homeostasis | |
| response to organic substance | |
| response to hypoxia | |
| response to cAMP | |
| carbohydrate metabolic process |
| Ariadne Ontology | Glycogen degradation |
|---|
| Group | Glycogen degradation |
|---|---|
| glycogen metabolic process | |
| glycogen catabolic process | |
| cellular calcium ion homeostasis | |
| response to organic substance | |
| response to hypoxia | |
| response to cAMP | |
| carbohydrate metabolic process | |
| nucleotide binding | |
| drug binding | |
| transferase activity | |
| sugar binding | |
| pyridoxal phosphate binding | |
| protein homodimerization activity | |
| AMP binding | |
| transferase activity, transferring glycosyl groups | |
| phosphorylase activity | |
| glycogen phosphorylase activity | |
| soluble fraction | |
| cytoplasm | |
| cytosol | |
| sarcoplasmic reticulum | |
| Z disc |
| MedScan ID | 5837 |
|---|
| Hugo ID | 9726 |
|---|
| Human chromosome position | 11q12-q13.2 |
|---|
| LocusLink ID | 5837 |
|---|---|
| 19309 | |
| 24701 |
| Alias | glycogen phosphorylase, muscle form |
|---|---|
| myophosphorylase | |
| AI115133 | |
| OTTMUSP00000020157 | |
| OTTMUSP00000023596 | |
| Muscpho | |
| muscle glycogen phosphorylase | |
| Phosphorylase, glycogen; muscle (McArdle syndrome) | |
| glycogen storage disease type V gene | |
| LOC361713 | |
| LOC82368 | |
| McArdle syndrome gene | |
| muscle glycogen phosphorylases | |
| muscle phosphorylase | |
| muscle phosphorylase a | |
| muscle phosphorylase b | |
| muscle phosphorylases | |
| Muscphos | |
| myophosphorylases | |
| phosphorylase, glycogen, muscle | |
| Phosphorylase, glycogen, muscle (McArdle syndrome) | |
| PYGM | |
| glycogen phosphorylase | |
| McArdle syndrome | |
| glycogen storage disease type V | |
| phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | |
| phosphorylase, glycogen, muscle (McArdle syndrome, glycogen storage disease |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 608455 |
|---|---|
| 232600 |
| Mouse chromosome position | 19 2.0 cM |
|---|
| GO ID | 0016208 |
|---|---|
| 0008144 | |
| 0008184 | |
| 0000166 | |
| 0030170 | |
| 0005529 | |
| 0016757 | |
| 0005975 | |
| 0006874 | |
| 0005980 | |
| 0005977 | |
| 0051591 | |
| 0001666 | |
| 0005737 | |
| 0005829 | |
| 0016529 | |
| 0005625 | |
| 0004645 | |
| 0016740 | |
| 0010033 | |
| 0030018 | |
| 0042803 | |
| 0005515 | |
| 0003824 |
| Rat chromosome position | 1q43 |
|---|
| Swiss-Prot Accession | A6NDY6 |
|---|---|
| P11217 | |
| Q9WUB3 | |
| Q9CTZ0 | |
| P09812 | |
| Q64607 | |
| A0AVK1 |
| PIR ID | A27335 |
|---|
| Unigene ID | Hs.154084 |
|---|---|
| Mm.27806 | |
| Rn.11238 |
| KEGG ID | hsa:5837 |
|---|---|
| mmu:19309 | |
| rno:24701 |
| EC Number | 2.4.1.1 |
|---|
| Swiss-Prot ID | PYGM_HUMAN |
|---|---|
| PYGM_MOUSE | |
| A6NDY6_HUMAN |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00218130 |
|---|---|
| IPI00225275 | |
| IPI00657751 | |
| IPI00831057 | |
| IPI00190181 | |
| IPI00895591 |
| Homologene ID | 2145 |
|---|
| RGD ID | 3461 |
|---|
| MGI ID | 97830 |
|---|