| URN | urn:agi-llid:5836 |
|---|---|
| Connectivity | 23 |
| Name | Pygl |
| Description | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) |
| Notes | catalyzes the rate-limiting step of glycogen catabolism [RGD] |
| Pathway | glycogen degradation pathway |
|---|
| GO Molecular Function | nucleotide binding |
|---|---|
| drug binding | |
| vitamin binding | |
| transferase activity | |
| purine binding | |
| sugar binding | |
| pyridoxal phosphate binding | |
| protein homodimerization activity | |
| AMP binding | |
| ATP binding | |
| bile acid binding | |
| glucose binding | |
| transferase activity, transferring glycosyl groups | |
| phosphorylase activity | |
| glycogen phosphorylase activity |
| GO Cellular Component | soluble fraction |
|---|---|
| cytoplasm |
| GO Biological Process | 5-phosphoribose 1-diphosphate biosynthetic process |
|---|---|
| glycogen metabolic process | |
| glycogen catabolic process | |
| carbohydrate metabolic process | |
| glucose homeostasis |
| Ariadne Ontology | Glycogen degradation |
|---|
| Group | Glycogen degradation |
|---|---|
| 5-phosphoribose 1-diphosphate biosynthetic process | |
| glycogen metabolic process | |
| glycogen catabolic process | |
| carbohydrate metabolic process | |
| glucose homeostasis | |
| nucleotide binding | |
| drug binding | |
| vitamin binding | |
| transferase activity | |
| purine binding | |
| sugar binding | |
| pyridoxal phosphate binding | |
| protein homodimerization activity | |
| AMP binding | |
| ATP binding | |
| bile acid binding | |
| glucose binding | |
| transferase activity, transferring glycosyl groups | |
| phosphorylase activity | |
| glycogen phosphorylase activity | |
| soluble fraction | |
| cytoplasm |
| MedScan ID | 5836 |
|---|
| Hugo ID | 9725 |
|---|
| Human chromosome position | 14q21-q22 |
|---|
| LocusLink ID | 5836 |
|---|---|
| 110095 | |
| 64035 |
| Alias | GSD6 |
|---|---|
| glycogen phosphorylase, liver form | |
| OTTMUSP00000031636 | |
| liver glycogen phosphorylase | |
| Lgp | |
| glycogen phosphorylase, liver | |
| glycogen storage disease type VI gene | |
| Hers disease gene | |
| liver glycogen phosphorylases | |
| Phosphorylase, glycogen, liver | |
| phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) gene | |
| PYGL | |
| Hers disease | |
| glycogen storage disease type VI | |
| phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | |
| phosphorylase, glycogen, liver (Hers disease, glycogen storage disease type |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 232700 |
|---|
| Mouse chromosome position | 12 30.0 cM |
|---|
| GO ID | 0016208 |
|---|---|
| 0005524 | |
| 0032052 | |
| 0008144 | |
| 0005536 | |
| 0008184 | |
| 0000166 | |
| 0042803 | |
| 0002060 | |
| 0030170 | |
| 0005529 | |
| 0016757 | |
| 0019842 | |
| 0006015 | |
| 0005975 | |
| 0042593 | |
| 0005980 | |
| 0005977 | |
| 0005737 | |
| 0005625 | |
| 0004645 | |
| 0016740 | |
| 0005730 | |
| 0005634 | |
| 0005886 | |
| 0003824 |
| Rat chromosome position | 6q24 |
|---|
| Swiss-Prot Accession | P06737 |
|---|---|
| Q6P1L4 | |
| Q3UKJ0 | |
| Q3TJQ7 | |
| Q3UEJ6 | |
| Q8BLV0 | |
| Q91WP9 | |
| Q9ET01 | |
| P09811 | |
| A6NDQ4 | |
| O60567 | |
| O60752 | |
| O60913 | |
| Q501V9 | |
| Q641R5 | |
| Q96G82 |
| PIR ID | A25518 |
|---|---|
| S22338 |
| Unigene ID | Hs.282417 |
|---|---|
| Mm.256926 | |
| Mm.447796 | |
| Rn.21399 |
| KEGG ID | hsa:5836 |
|---|---|
| mmu:110095 | |
| rno:64035 |
| EC Number | 2.4.1.1 |
|---|
| Swiss-Prot ID | PYGL_HUMAN |
|---|---|
| PYGL_RAT | |
| Q3UKJ0_MOUSE | |
| Q91WP9_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00783313 |
|---|---|
| IPI00190179 | |
| IPI00653254 | |
| IPI00787186 | |
| IPI00319525 | |
| IPI00856665 |
| Homologene ID | 84371 |
|---|
| RGD ID | 620687 |
|---|
| MGI ID | 97829 |
|---|