| URN | urn:agi-llid:2632 |
|---|---|
| Connectivity | 5 |
| Name | Gbe1 |
| Description | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) |
| Notes | This monomeric enzyme functions in glycogen symthesis by catalyzing the formation of alpha 1,6- glucosidic linkages. It is most highly expressed in liver and muscle. Deficiency can result in glycogen storage disease IV (Andersen's disease). |
| Pathway | glycogen biosynthetic pathway |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| transferase activity | |
| cation binding | |
| sugar binding | |
| transferase activity, transferring glycosyl groups | |
| 1,4-alpha-glucan branching enzyme activity | |
| hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO Cellular Component | soluble fraction |
|---|---|
| cytosol |
| GO Biological Process | generation of precursor metabolites and energy |
|---|---|
| glycogen biosynthetic process | |
| glycogen metabolic process | |
| carbohydrate metabolic process |
| Ariadne Ontology | Glycogen synthesis |
|---|
| Group | Glycogen synthesis |
|---|---|
| catalytic activity | |
| generation of precursor metabolites and energy | |
| glycogen biosynthetic process | |
| glycogen metabolic process | |
| carbohydrate metabolic process | |
| transferase activity | |
| cation binding | |
| sugar binding | |
| transferase activity, transferring glycosyl groups | |
| 1,4-alpha-glucan branching enzyme activity | |
| hydrolase activity, hydrolyzing O-glycosyl compounds | |
| soluble fraction | |
| cytosol |
| MedScan ID | 2632 |
|---|
| Hugo ID | 4180 |
|---|
| Human chromosome position | 3p12.3 |
|---|
| LocusLink ID | 2632 |
|---|---|
| 74185 | |
| 288333 |
| Alias | GBE |
|---|---|
| 1,4-alpha-glucan-branching enzyme | |
| brancher enzyme | |
| OTTHUMP00000213833 | |
| glycogen branching enzyme | |
| glycogen-branching enzyme | |
| amylo-(1,4 to 1,6) transglucosidase | |
| amylo-(1,4 to 1,6) transglycosylase | |
| D16Ertd536e | |
| 2310045H19Rik | |
| 2810426P10Rik | |
| 1,4-alpha-glucan branching enzyme | |
| 2310045H19 | |
| 2810426P10 | |
| branching enzyme 1 | |
| branching enzyme I | |
| DNA segment, Chr 16, ERATO Doi 536, expressed | |
| Gbe I | |
| Gbe1 | |
| glucan (1,4-alpha-), branching enzyme | |
| glucan (1,4-alpha-), branching enzyme 1 | |
| glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme) | |
| glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Anderse | |
| glucan (1,4-alpha-), branching enzyme I | |
| glycogen storage disease type IV gene | |
| Glycogen branching enzyme | |
| RIKEN cDNA 2810426P10 gene | |
| glucan (1,4-alpha-) |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 607839 |
|---|---|
| 232500 |
| Mouse chromosome position | 16 41.9 cM |
|---|
| GO ID | 0003844 |
|---|---|
| 0043169 | |
| 0004553 | |
| 0016757 | |
| 0005975 | |
| 0006091 | |
| 0005978 | |
| 0005977 | |
| 0005829 | |
| 0003824 | |
| 0005529 | |
| 0016740 | |
| 0005625 | |
| 0005575 | |
| 0003674 | |
| 0008150 | |
| 0004556 |
| Rat chromosome position | 11p11 |
|---|
| Swiss-Prot Accession | B3KWV3 |
|---|---|
| Q04446 | |
| Q59ET0 | |
| Q9D6Y9 | |
| Q8BT78 | |
| Q8C7E6 | |
| Q5EB55 | |
| Q96EN0 |
| PIR ID | A46075 |
|---|
| Unigene ID | Hs.436062 |
|---|---|
| Mm.396102 | |
| Rn.29938 |
| KEGG ID | hsa:2632 |
|---|---|
| mmu:74185 | |
| rno:288333 |
| EC Number | 2.4.1.18 |
|---|
| Swiss-Prot ID | GLGB_MOUSE |
|---|---|
| GLGB_HUMAN | |
| B3KWV3_HUMAN | |
| Q5EB55_RAT | |
| Q59ET0_HUMAN |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00109823 |
|---|---|
| IPI00296635 | |
| IPI00363180 | |
| IPI00793109 | |
| IPI00789251 | |
| IPI00458769 | |
| IPI00565915 |
| Homologene ID | 129 |
|---|
| RGD ID | 1309968 |
|---|
| MGI ID | 1921435 |
|---|