| URN | urn:agi-llid:2773 |
|---|---|
| Connectivity | 91 |
| Name | Gnai3 |
| Description | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
| Notes | has GTPase activity; involved in zymogen granule-plasma membrane fusion in pancreatic cells [RGD] |
| Pathway | CannabinoidR -> AP-1/EGR signaling |
|---|---|
| NeuropeptideYR -> ATF/CREB signaling | |
| SerotoninR1 -> FOS signaling | |
| angiotensin II signaling pathway via AT2 receptor |
| GO Molecular Function | signal transducer activity |
|---|---|
| nucleotide binding | |
| metabotropic serotonin receptor binding | |
| guanyl nucleotide binding | |
| GTP binding | |
| GTPase activity |
| GO Cellular Component | plasma membrane |
|---|---|
| cytoplasm | |
| membrane raft | |
| Golgi apparatus | |
| Golgi membrane | |
| zymogen granule | |
| membrane fraction | |
| heterotrimeric G-protein complex |
| GO Biological Process | transport |
|---|---|
| negative regulation of synaptic transmission | |
| regulation of heart contraction | |
| signal transduction | |
| negative regulation of adenylate cyclase activity | |
| vesicle fusion | |
| negative regulation of secretion | |
| G-protein coupled receptor protein signaling pathway |
| Ariadne Ontology | Gi-o |
|---|
| Group | Gi-o |
|---|---|
| transport | |
| negative regulation of synaptic transmission | |
| regulation of heart contraction | |
| signal transduction | |
| negative regulation of adenylate cyclase activity | |
| vesicle fusion | |
| negative regulation of secretion | |
| G-protein coupled receptor protein signaling pathway | |
| signal transducer activity | |
| nucleotide binding | |
| metabotropic serotonin receptor binding | |
| guanyl nucleotide binding | |
| GTP binding | |
| GTPase activity | |
| plasma membrane | |
| cytoplasm | |
| membrane raft | |
| Golgi apparatus | |
| Golgi membrane | |
| zymogen granule | |
| membrane fraction | |
| heterotrimeric G-protein complex |
| MedScan ID | 2773 |
|---|
| Hugo ID | 4387 |
|---|
| Human chromosome position | 1p13 |
|---|
| LocusLink ID | 2773 |
|---|---|
| 14679 | |
| 25643 |
| Alias | 87U6 |
|---|---|
| FLJ26559 | |
| RP5-1160K1.2 | |
| guanine nucleotide-binding protein G(k) subunit alpha | |
| g(i) alpha-3 | |
| Gnai-3 | |
| AI158965 | |
| AW537698 | |
| Galphai3 | |
| RP23-89M15.4 | |
| OTTMUSP00000007641 | |
| guanine nucleotide binding protein, alpha inhibiting 3 | |
| GIP3A | |
| Guanine nucleotide binding, protein, alpha inhibiting polypeptide 3 | |
| G alpha i3 | |
| G protein alpha inhibiting activity polypeptide 3 | |
| G protein alpha inhibiting activity polypeptide III | |
| G(i) alpha III | |
| G(i3) | |
| G(k) alpha | |
| Gnai3 | |
| guanine nucleotide binding protein (G protein), alpha inhibiting 3 | |
| guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | |
| guanine nucleotide binding protein, alpha inhibiting III | |
| Guanine nucleotide-binding protein G(k), alpha subunit | |
| LOC126995 | |
| OTTHUMP00000013368 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 139370 |
|---|
| Mouse chromosome position | 3 48.8 cM |
|---|
| GO ID | 0005525 |
|---|---|
| 0003924 | |
| 0019001 | |
| 0031821 | |
| 0000166 | |
| 0004871 | |
| 0007186 | |
| 0007194 | |
| 0050805 | |
| 0006810 | |
| 0006906 | |
| 0005794 | |
| 0005737 | |
| 0005624 | |
| 0045121 | |
| 0005886 | |
| 0042588 | |
| 0008016 | |
| 0007165 | |
| 0005834 | |
| 0051048 | |
| 0000139 |
| Rat chromosome position | 2q34 |
|---|
| Swiss-Prot Accession | P08754 |
|---|---|
| Q5TZX1 | |
| Q9DC51 | |
| Q3TJH1 | |
| P08753 | |
| Q45QM8 | |
| P17539 | |
| A2AE36 | |
| Q3TGV1 | |
| Q61019 |
| PIR ID | E27423 |
|---|---|
| S02348 |
| Unigene ID | Hs.73799 |
|---|---|
| Mm.271703 | |
| Rn.4368 |
| KEGG ID | hsa:2773 |
|---|---|
| mmu:14679 | |
| rno:25643 |
| Swiss-Prot ID | GNAI3_RAT |
|---|---|
| GNAI3_HUMAN | |
| GNAI3_MOUSE | |
| Q5TZX1_HUMAN | |
| A2AE36_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00231726 |
|---|---|
| IPI00220578 | |
| IPI00338854 |
| Homologene ID | 55975 |
|---|
| RGD ID | 2714 |
|---|
| MGI ID | 95773 |
|---|