Protein Gna11

URN	urn:agi-llid:2767
Total Entities	0
Connectivity	403
Name	Gna11
Description	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Notes	may be involved in mediating second messenger signals from the endothelin receptor in adipocytes [RGD]

Ariadne Ontology	Gq
	Secreted proteins
	Biofluids assayable substances

GO Molecular Function	protein complex binding
	G-protein beta-gamma-subunit complex binding
	G-protein coupled receptor binding
	type 2A serotonin receptor binding
	nucleotide binding
	GTP binding
	guanyl nucleotide binding
	metal ion binding
	GTPase activity
	signal transducer activity

GO Cellular Component	membrane
	extrinsic to internal side of plasma membrane
	heterotrimeric G-protein complex
	protein complex
	plasma membrane
	cytoplasm
	cytosol

GO Biological Process	signal transduction
	G-protein coupled receptor signaling pathway
	glutamate receptor signaling pathway
	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
	phospholipase C-activating dopamine receptor signaling pathway
	regulation of melanocyte differentiation
	platelet activation
	GTP catabolic process
	protein ADP-ribosylation
	regulation of action potential
	developmental pigmentation
	skeletal system development
	heart development
	blood coagulation

Pathway	VasopressinR1 -> MEF/MYOD/NFATC/MYOG signaling
	VasopressinR1 -> STAT signaling
	VasopressinR1 -> CREB/ELK-SRF/AP-1/EGR signaling
	EndothelinRb -> AP-1/CREB/ELK-SRF signaling
	AdrenergicRb -> CREB signaling
	EndothelinRa -> AP-1/CREB signaling
	AdrenergicRb -> STAT3 signaling
	AVP/Gq -> STAT Expression Targets
	AVP/Gq -> MEF/MYOD/NFATC/MYOG Expression Targets
	AVP/Gq -> CREB/ELK-SRF/AP-1/EGR Expression Targets
	Epinephrine/Gs Expression Targets
	Noradrenaline/Gs Expression Targets
	EDN1 Expression Targets
	EDN3 Expression Targets
	angiotensin II signaling pathway via AT1 receptor
	angiotensin II signaling pathway via AT1 receptor

Group	Gq
	signal transduction
	G-protein coupled receptor signaling pathway
	glutamate receptor signaling pathway
	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
	phospholipase C-activating dopamine receptor signaling pathway
	regulation of melanocyte differentiation
	platelet activation
	GTP catabolic process
	protein ADP-ribosylation
	regulation of action potential
	developmental pigmentation
	skeletal system development
	heart development
	blood coagulation
	protein complex binding
	G-protein beta-gamma-subunit complex binding
	G-protein coupled receptor binding
	type 2A serotonin receptor binding
	nucleotide binding
	GTP binding
	guanyl nucleotide binding
	metal ion binding
	GTPase activity
	signal transducer activity
	membrane
	extrinsic to internal side of plasma membrane
	heterotrimeric G-protein complex
	protein complex
	plasma membrane
	cytoplasm
	cytosol
	Secreted proteins
	Biofluids assayable substances

MedScan ID	2767

Hugo ID	4379

Human chromosome position	19p13.3

Alias	GNA-11
	guanine nucleotide-binding protein subunit alpha-11
	g alpha-11
	G-protein subunit alpha-11
	guanine nucleotide-binding protein, Gq class, GNA11
	guanine nucleotide-binding protein G(y) subunit alpha
	Dsk7
	E430025L19
	guanine nucleotide regulatory protein G alpha 11
	guanine nucleotide-binding protein alpha 11 subunit
	GA11
	guanine nucleotide binding protein, alpha 11
	Guanine nucleotide-binding protein G(Y), alpha subunit
	LOC126290
	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
	Guanine nucleotide-binding, Gq class, GNA
	G protein alpha 11
	G protein alpha 11 subunit
	Galpha q-11
	Galphaq-11
	Gna11
	G(Y), alpha 11 subunit
	likely ortholog of mouse G protein couple-dreceptor alpha 11

OMIM ID	139313

Cell Localization	Cell membrane
	Cytoplasm

Mouse chromosome position	10 43.0 cM

Rat chromosome position	7q11

Homologene ID	20474

MGI ID	95766

RGD ID	619749

Primary Cell Localization	Cytoplasm