| URN | urn:agi-llid:11608 |
|---|---|
| Total Entities | 0 |
| Connectivity | 5 |
| Name | Agtr1b |
| Description | angiotensin II receptor, type 1b |
| Notes | G-protein coupled receptor for angiotensin II; has a role in blood pressure regulation, electrolyte balance and cardiac function [RGD] |
| GO Molecular Function | protein self-association |
|---|---|
| bradykinin receptor binding | |
| protein heterodimerization activity | |
| peptide hormone binding | |
| acetyltransferase activator activity | |
| G-protein coupled receptor activity | |
| angiotensin type II receptor activity | |
| angiotensin type I receptor activity | |
| signal transducer activity |
| GO Cellular Component | membrane |
|---|---|
| vesicle membrane | |
| vesicle lumen | |
| basolateral plasma membrane | |
| integral to membrane | |
| plasma membrane |
| GO Biological Process | signal transduction |
|---|---|
| Rho protein signal transduction | |
| calcium-mediated signaling | |
| G-protein coupled receptor signaling pathway | |
| phospholipase C-activating angiotensin-mediated signaling pathway | |
| positive regulation of cellular protein metabolic process | |
| positive regulation of cholesterol esterification | |
| negative regulation of neuron apoptotic process | |
| elevation of cytosolic calcium ion concentration | |
| elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | |
| cell chemotaxis | |
| cellular response to dexamethasone stimulus | |
| response to stress | |
| response to drug | |
| response to nutrient | |
| response to estrogen stimulus | |
| response to hypoxia | |
| inflammatory response | |
| drinking behavior | |
| positive regulation of branching involved in ureteric bud morphogenesis | |
| regulation of vasoconstriction | |
| positive regulation of phospholipase A2 activity | |
| blood vessel development | |
| kidney development | |
| brain renin-angiotensin system | |
| regulation of systemic arterial blood pressure by circulatory renin-angiotensin | |
| regulation of renal output by angiotensin | |
| renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure |
| Pathway | renin-angiotensin system signaling pathway |
|---|---|
| angiotensin II signaling pathway | |
| angiotensin II signaling pathway via AT1 receptor | |
| renin-angiotensin cascade pathway | |
| angiotensin II signaling pathway via AT1 receptor |
| Group | signal transduction |
|---|---|
| Rho protein signal transduction | |
| calcium-mediated signaling | |
| G-protein coupled receptor signaling pathway | |
| phospholipase C-activating angiotensin-mediated signaling pathway | |
| positive regulation of cellular protein metabolic process | |
| positive regulation of cholesterol esterification | |
| negative regulation of neuron apoptotic process | |
| elevation of cytosolic calcium ion concentration | |
| elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | |
| cell chemotaxis | |
| cellular response to dexamethasone stimulus | |
| response to stress | |
| response to drug | |
| response to nutrient | |
| response to estrogen stimulus | |
| response to hypoxia | |
| inflammatory response | |
| drinking behavior | |
| positive regulation of branching involved in ureteric bud morphogenesis | |
| regulation of vasoconstriction | |
| positive regulation of phospholipase A2 activity | |
| blood vessel development | |
| kidney development | |
| brain renin-angiotensin system | |
| regulation of systemic arterial blood pressure by circulatory renin-angiotensin | |
| regulation of renal output by angiotensin | |
| renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure | |
| protein self-association | |
| bradykinin receptor binding | |
| protein heterodimerization activity | |
| peptide hormone binding | |
| acetyltransferase activator activity | |
| G-protein coupled receptor activity | |
| angiotensin type II receptor activity | |
| angiotensin type I receptor activity | |
| signal transducer activity | |
| membrane | |
| vesicle membrane | |
| vesicle lumen | |
| basolateral plasma membrane | |
| integral to membrane | |
| plasma membrane |
| MedScan ID | 11608 |
|---|
| LocusLink ID | 11608 |
|---|---|
| 81638 |
| Alias | AT1B |
|---|---|
| AT2R1B | |
| Agtr-1b | |
| Angtr-1b | |
| type-1B angiotensin II receptor | |
| AT3 | |
| angiotensin II type-1B receptor | |
| AT1 | |
| Agtr1 | |
| AT<sub>1</sub>R | |
| angiotensin receptor 1 | |
| angiotensin receptor 1b | |
| angiotensin II type-1 receptor | |
| angiotensin II receptor, type-1 | |
| Angiotensin II receptor, type 1 (AT1B) | |
| MGC129325 |
| Organism | Mus musculus |
|---|---|
| Rattus norvegicus |
| Unigene ID | Mm.134863 |
|---|---|
| Rn.9815 |
| KEGG ID | mmu:11608 |
|---|---|
| rno:81638 |
| Swiss-Prot Accession | P29755 |
|---|---|
| Q32MF7 | |
| Q8BU69 | |
| P29089 |
| GO ID | 0004930 |
|---|---|
| 0010698 | |
| 0001596 | |
| 0004945 | |
| 0031711 | |
| 0017046 | |
| 0046982 | |
| 0043621 | |
| 0004871 | |
| 0007186 | |
| 0007266 | |
| 0001568 | |
| 0002035 | |
| 0019722 | |
| 0060326 | |
| 0071549 | |
| 0042756 | |
| 0007204 | |
| 0051482 | |
| 0006954 | |
| 0001822 | |
| 0043524 | |
| 0086097 | |
| 0090190 | |
| 0032270 | |
| 0010873 | |
| 0032430 | |
| 0001991 | |
| 0019229 | |
| 0043627 | |
| 0007165 | |
| 0016323 | |
| 0016021 | |
| 0016020 | |
| 0005886 | |
| 0031983 | |
| 0012506 | |
| 0002019 | |
| 0001999 | |
| 0042493 | |
| 0001666 | |
| 0007584 | |
| 0006950 | |
| 0004872 |
| PIR ID | A42656 |
|---|---|
| JQ1516 | |
| JC1194 |
| Swiss-Prot ID | AGTRB_RAT |
|---|---|
| AGTRB_MOUSE | |
| Q8BU69_MOUSE | |
| Q32MF7_MOUSE |
| Cell Localization | Cell membrane |
|---|
| IPI ID | IPI00325460 |
|---|---|
| IPI00323276 |
| Mouse chromosome position | 3 7.6 cM |
|---|
| Rat chromosome position | 2q24 |
|---|
| Homologene ID | 84871 |
|---|
| MGI ID | 87965 |
|---|
| RGD ID | 2071 |
|---|