| URN | urn:agi-llid:4793 |
|---|---|
| Total Entities | 0 |
| Connectivity | 245 |
| Name | Nfkbib |
| Description | nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta |
| Notes | a stress protein inducible by hyperthermia or proteasome inhibitors [RGD] |
| Ariadne Ontology | NFKBI |
|---|---|
| Biofluids assayable substances |
| GO Molecular Function | NF-kappaB binding |
|---|---|
| transcription coactivator activity | |
| signal transducer activity |
| GO Cellular Component | I-kappaB-NF-kappaB complex |
|---|---|
| cytoplasm | |
| cytosol | |
| nucleus |
| GO Biological Process | cytoplasmic sequestering of NF-kappaB |
|---|---|
| signal transduction | |
| toll-like receptor signaling pathway | |
| toll-like receptor 2 signaling pathway | |
| toll-like receptor 3 signaling pathway | |
| toll-like receptor 4 signaling pathway | |
| MyD88-dependent toll-like receptor signaling pathway | |
| MyD88-independent toll-like receptor signaling pathway | |
| toll-like receptor 1 signaling pathway | |
| TRIF-dependent toll-like receptor signaling pathway | |
| Toll signaling pathway | |
| positive regulation of NF-kappaB transcription factor activity | |
| transcription, DNA-dependent | |
| innate immune response | |
| positive regulation of type I interferon production |
| Pathway | nuclear factor kappa B signaling pathway |
|---|---|
| nuclear factor kappa B signaling pathway | |
| nuclear factor kappa B signaling pathway |
| Group | NFKBI |
|---|---|
| cytoplasmic sequestering of NF-kappaB | |
| signal transduction | |
| toll-like receptor signaling pathway | |
| toll-like receptor 2 signaling pathway | |
| toll-like receptor 3 signaling pathway | |
| toll-like receptor 4 signaling pathway | |
| MyD88-dependent toll-like receptor signaling pathway | |
| MyD88-independent toll-like receptor signaling pathway | |
| toll-like receptor 1 signaling pathway | |
| TRIF-dependent toll-like receptor signaling pathway | |
| Toll signaling pathway | |
| positive regulation of NF-kappaB transcription factor activity | |
| transcription, DNA-dependent | |
| innate immune response | |
| positive regulation of type I interferon production | |
| NF-kappaB binding | |
| transcription coactivator activity | |
| signal transducer activity | |
| I-kappaB-NF-kappaB complex | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| Biofluids assayable substances |
| Source | Curated |
|---|---|
| GO component |
| MedScan ID | 4793 |
|---|
| Hugo ID | 7798 |
|---|
| Human chromosome position | 19q13.1 |
|---|
| LocusLink ID | 4793 |
|---|---|
| 18036 | |
| 81525 | |
| 525408 |
| Alias | IKBB |
|---|---|
| TRIP9 | |
| NF-kappa-B inhibitor beta | |
| ikB-B | |
| TRIP-9 | |
| ikB-beta | |
| ikappaBbeta | |
| NF-kappa-BIB | |
| I-kappa-B-beta | |
| TR-interacting protein 9 | |
| thyroid receptor-interacting protein 9 | |
| IkB | |
| I(Kappa)B(beta) | |
| nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta | |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | |
| TR- interactive protein 9 | |
| OTTMUSP00000018309 | |
| Thyroid receptor interacting protein 9 | |
| Thyroid receptor interactive protein 9 | |
| TR- interacting protein 9 | |
| TR- interactive protein IX | |
| Nfkbib | |
| Thyroid receptor interactive protein IX | |
| OTTMUSP00000018308 | |
| IkBbeta | |
| MGC36057 | |
| MGC93398 | |
| NF-kappaB inhibitor beta |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus | |
| Bos taurus |
| OMIM ID | 604495 |
|---|
| Unigene ID | Hs.9731 |
|---|---|
| Mm.220333 | |
| Rn.8395 | |
| Mm.379654 | |
| Bt.20178 |
| KEGG ID | hsa:4793 |
|---|---|
| mmu:18036 | |
| rno:81525 |
| Swiss-Prot Accession | Q15653 |
|---|---|
| Q60778 | |
| Q5U342 | |
| Q9JIA3 | |
| Q564F1 | |
| Q9D6L5 | |
| A8K3F4 | |
| Q96BJ7 | |
| Q96LS1 | |
| Q59EM7 | |
| Q80WN0 | |
| Q80WN1 | |
| Q8VC27 | |
| IKBB_HUMAN | |
| IKBB_RAT |
| GO ID | 0004871 |
|---|---|
| 0003713 | |
| 0002755 | |
| 0002756 | |
| 0035666 | |
| 0008063 | |
| 0007253 | |
| 0045087 | |
| 0051092 | |
| 0032481 | |
| 0007165 | |
| 0034130 | |
| 0034134 | |
| 0034138 | |
| 0034142 | |
| 0002224 | |
| 0006351 | |
| 0005829 | |
| 0005634 | |
| 0005737 | |
| 0051059 | |
| 0033256 | |
| 0006350 | |
| 0005515 | |
| 0004872 |
| Swiss-Prot ID | IKBB_MOUSE |
|---|---|
| IKBB_HUMAN | |
| Q5U342_RAT | |
| Q564F1_MOUSE | |
| Q96LS1_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| Nucleus |
| IPI ID | IPI00310330 |
|---|---|
| IPI00161119 | |
| IPI00514744 | |
| IPI00480740 | |
| IPI00556848 | |
| IPI00387046 | |
| IPI00474801 | |
| IPI00200350 | |
| IPI00388959 |
| Mouse chromosome position | 7 |
|---|---|
| 7 A3-B3 |
| Rat chromosome position | 1q21 |
|---|
| Homologene ID | 37631 |
|---|
| MGI ID | 104752 |
|---|
| RGD ID | 621887 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|
| Homo sapiens Chromosome position | 19q13.1 |
|---|
| Microarray ID | 99982_at |
|---|
| FunctionalClass | protein binding |
|---|---|
| receptor | |
| signal transducer | |
| transcription coactivator |
| Mus musculus Chromosome position | 7 A3-B3 |
|---|
| KEGG pathway | Adipocytokine signaling pathway |
|---|---|
| B cell receptor signaling pathway | |
| T cell receptor signaling pathway |
| Rattus norvegicus Chromosome position | 1q21 |
|---|
| Bos taurus Chromosome position | 18 |
|---|