| URN | urn:agi-llid:90226 |
|---|---|
| Connectivity | 47 |
| Name | Ucn2 |
| Description | urocortin 2 |
| Notes | This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq] |
| Pathway | corticotropin-releasing hormone signaling pathway |
|---|
| GO Molecular Function | hormone binding |
|---|---|
| receptor binding | |
| hormone activity | |
| G-protein-coupled receptor binding |
| GO Cellular Component | extracellular region |
|---|---|
| extracellular space |
| GO Biological Process | cell proliferation |
|---|---|
| digestion | |
| response to stress | |
| tissue regeneration | |
| negative regulation of gonadotropin secretion | |
| cAMP biosynthetic process | |
| cellular response to glucocorticoid stimulus |
| Group | extracellular region |
|---|---|
| cell proliferation | |
| digestion | |
| response to stress | |
| tissue regeneration | |
| negative regulation of gonadotropin secretion | |
| cAMP biosynthetic process | |
| cellular response to glucocorticoid stimulus | |
| hormone binding | |
| receptor binding | |
| hormone activity | |
| G-protein-coupled receptor binding | |
| extracellular space |
| MedScan ID | 90226 |
|---|
| Hugo ID | 18414 |
|---|
| Human chromosome position | 3p21.3 |
|---|
| LocusLink ID | 90226 |
|---|---|
| 170896 |
| Alias | UR |
|---|---|
| SRP | |
| URP | |
| UCNI | |
| UCN-II | |
| urocortin-2 | |
| ucn II | |
| urocortin II | |
| urocortin-related peptide | |
| stresscopin-related peptide | |
| Ucn3 | |
| urocortin 3 |
| Organism | Homo sapiens |
|---|---|
| Rattus norvegicus |
| OMIM ID | 605902 |
|---|
| GO ID | 0001664 |
|---|---|
| 0005179 | |
| 0042562 | |
| 0005102 | |
| 0006171 | |
| 0008283 | |
| 0007586 | |
| 0006950 | |
| 0005576 | |
| 0071385 | |
| 0032277 | |
| 0042246 | |
| 0005615 |
| Rat chromosome position | 8q32 |
|---|
| Swiss-Prot Accession | Q96RP3 |
|---|---|
| A1YKY4 | |
| Q91WW1 | |
| Q9BUG0 |
| Unigene ID | Hs.631914 |
|---|---|
| Rn.153037 |
| KEGG ID | hsa:90226 |
|---|---|
| rno:170896 |
| Swiss-Prot ID | UCN2_HUMAN |
|---|---|
| UCN2_RAT | |
| A1YKY4_RAT |
| Cell Localization | Secreted |
|---|
| IPI ID | IPI00030945 |
|---|---|
| IPI00207163 |
| Homologene ID | 50048 |
|---|
| RGD ID | 620765 |
|---|