Protein Atp6ap2

URN urn:agi-llid:10159
Connectivity 51
Name Atp6ap2
Description ATPase, H+ transporting, lysosomal accessory protein 2
Notes This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq]

Pathway renin-angiotensin system signaling pathway
Copy oenin-angiotensin cascade pathway
renin-angiotensin cascade pathway

GO Molecular Function receptor activity

GO Cellular Component membrane
external side of plasma membrane
integral to membrane

GO Biological Process positive regulation of transforming growth factor-beta1 production
regulation of MAPKKK cascade
angiotensin maturation

Ariadne Ontology Lysosomal H+ import

Group Lysosomal H+ import
positive regulation of transforming growth factor-beta1 production
regulation of MAPKKK cascade
angiotensin maturation
receptor activity
membrane
external side of plasma membrane
integral to membrane

MedScan ID 10159

Hugo ID 18305

Human chromosome position Xp11.4

LocusLink ID 10159
70495
302526

Alias M8-9
MRXE
XMRE
HT028
ELDF10
ATP6IP2
MSTP009
APT6M8-9
ATP6M8-9
MGC99577
renin receptor
N14F
OTTHUMP00000025770
OTTHUMP00000025773
OTTHUMP00000025774
V-ATPase M8.9 subunit
renin/prorenin receptor
ER-localized type I transmembrane adaptor
embryonic liver differentiation factor 10
ATPase H(+)-transporting lysosomal-interacting protein 2
ATPase, H+ transporting, lysosomal interacting protein 2
vacuolar ATP synthase membrane sector-associated protein M8-9
vacuolar proton ATP synthase membrane sector associated protein M8-9
ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9
(P)RR
5730403E06Rik
RP24-392J24.1
OTTMUSP00000018429
(pro)renin receptor
ATPase, H+ transporting, lysosomal interacting protein 1
MGC94783
ATPase, H(+)-transporting, lysosomal-interacting protein 2
5730403E06
APT6M8 IX
ATP6AP2
ATP6M8 IX
ATPase membrane sector associated protein M8 IX
ATPase membrane sector associated protein M8-9
ATPase, H transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9
ATPase, H transporting, lysosomal accessory protein 2
ATPase, H transporting, lysosomal accessory protein II
ATPase, H transporting, lysosomal interacting protein 2
ATPase, H transporting, lysosomal interacting protein II
ATPase, H transporting, lysosomal interactive protein 2
ATPase, H transporting, lysosomal interactive protein II
ATPase, H+ transporting, lysosomal accessory protein 2
ATPase, H+ transporting, lysosomal accessory protein II
ATPase, H+ transporting, lysosomal interacting protein II
ATPase, H+ transporting, lysosomal interactive protein 2
ATPase, H+ transporting, lysosomal interactive protein II
LOC95880
M8 IX
Mental retardation, X-linked, with epilepsy gene
OTTHUMP00000025771
renin receptors
vacuolar ATP synthase membrane sector associated protein M8 IX
vacuolar ATP synthase membrane sector associated protein M8-9
vacuolar ATP synthetase membrane sector associated protein M8 IX
vacuolar ATP synthetase membrane sector associated protein M8-9
vacuolar proton ATP synthetase membrane sector associated protein M8-9

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000023
NM_005765
NP_005756
NT_079573
NW_927701
NW_001842361
NG_008874
AC_000066
AC_000155
AC092473
AF354120
AAL11062
CH471141
EAW59424
AF109363
AAQ13511
AF248966
AAG44564
AF291814
AAM47531
AK075382
BAC11582
AK293510
BAH11525
AK296614
BAH12399
AK297007
BAH12473
AK297760
BAH12660
AK314633
AK315948
BAH14319
AL049929
CAB43210
AY038990
AAK83467
AY429341
AAR06910
BC010395
AAH10395
BC084541
AAH84541
Y17975
CAA76984
O75787
Q96PH0
NC_000086
NM_027439
NP_081715
NT_039700
NW_001035161
AC_000042
BX000537
CAM27889
AB192471
BAE92936
AK017482
BAB30766
AK029405
BAC26436
AK076495
BAC36365
AK151735
AK168139
AW475779
AW985491
BC014706
AAH14706
BY784908
Q1XID4
Q9CYN9
NC_005120
XM_217592
XP_217592
NW_048034
NW_001091912
XM_001060853
XP_001060853
AC_000089
CH474009
EDL97631
EDL97632
EDL97633
AB188298
BAD67178
BC079339
AAH79339
Q6AXS4

OMIM ID 300556
300423

Mouse chromosome position X

GO ID 0004872
0002003
0032914
0043408
0009897
0016021
0016020

Rat chromosome position Xq13

Swiss-Prot Accession O75787
Q96PH0
Q9CYN9
Q1XID4
Q6AXS4
A2BDN5
Q8BVU6
Q91YU5
Q5QTQ7
Q6T7F5
Q8NBP3
Q8NG15
Q96FV6
Q96LB5
Q9H2P8
Q9UG89

PIR ID T08667

Unigene ID Hs.495960
Mm.25148
Rn.12944

KEGG ID hsa:10159
mmu:70495
rno:302526

Swiss-Prot ID RENR_MOUSE
RENR_HUMAN
A2BDN5_MOUSE

Cell Localization Membrane
Lysosome

IPI ID IPI00459331
IPI00168884
IPI00642797
IPI00642918
IPI00872971
IPI00358308

Homologene ID 38097

RGD ID 1561269

MGI ID 1917745