| URN | urn:agi-llid:51156 |
|---|---|
| Total Entities | 0 |
| Connectivity | 59 |
| Name | Serpina10 |
| Description | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| Notes | The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010] |
| GO Molecular Function | peptidase inhibitor activity |
|---|---|
| serine-type endopeptidase inhibitor activity | |
| heparin binding |
| GO Cellular Component | extracellular region |
|---|---|
| extracellular space |
| GO Biological Process | regulation of acrosome reaction |
|---|---|
| hemostasis | |
| blood coagulation | |
| tissue regeneration | |
| regulation of proteolysis | |
| negative regulation of peptidase activity | |
| negative regulation of endopeptidase activity |
| Pathway | Coagulation Cascade |
|---|---|
| coagulation cascade pathway |
| Group | regulation of acrosome reaction |
|---|---|
| hemostasis | |
| blood coagulation | |
| tissue regeneration | |
| regulation of proteolysis | |
| peptidase inhibitor activity | |
| serine-type endopeptidase inhibitor activity | |
| negative regulation of peptidase activity | |
| negative regulation of endopeptidase activity | |
| heparin binding | |
| extracellular region | |
| extracellular space | |
| Secreted proteins |
| LocusLink ID | 51156 |
|---|---|
| 217847 | |
| 171154 |
| Cell Localization | Secreted |
|---|
| GO ID | 0008201 |
|---|---|
| 0004867 | |
| 0007596 | |
| 0010951 | |
| 0060046 | |
| 0030162 | |
| 0005615 | |
| 0030414 | |
| 0007599 | |
| 0010466 | |
| 0005576 | |
| 0042246 |
| Alias | PZI |
|---|---|
| ZPI | |
| UNQ707/PRO1358 | |
| protein Z-dependent protease inhibitor | |
| serpin A10 | |
| PZ-dependent protease inhibitor | |
| serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | |
| Rasp1 | |
| RASP-1 | |
| regeneration-associated serpin 1 | |
| serpin peptidase inhibitor, clade A, member 10 | |
| plasma protein associated with liver regeneration | |
| serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | |
| serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiprotease, antitrypsin), member 10 | |
| serine (or cysteine) protease inhibitor, clade A (alpha-1 antiprotease, antitrypsin), member 10 | |
| Serpina10 | |
| serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | |
| serpin peptidase inhibitor, clade A (alpha-1 antiprotease, antitrypsin), member 10 | |
| CENTERIN | |
| Rasp I | |
| MGC108600 | |
| MGC25863 | |
| OTTMUSP00000032369 | |
| protein Z-dependent protease inhibitorprecursor | |
| protein Z-dependent proteinase inhibitor | |
| protein Z-dependent proteinase inhibitorprecursor | |
| PZ-dependent proteinase inhibitor |
| Mouse chromosome position | 12 |
|---|
| OMIM ID | 605271 |
|---|
| Rat chromosome position | 6q32 |
|---|
| Hugo ID | 15996 |
|---|
| Human chromosome position | 14q32.13 |
|---|
| Swiss-Prot Accession | Q9UK55 |
|---|---|
| Q8R121 | |
| Q62975 | |
| Q8VCV8 | |
| A5Z2A5 | |
| Q6UWX9 | |
| Q86U20 |
| Unigene ID | Hs.118620 |
|---|---|
| Mm.29094 | |
| Rn.10502 |
| KEGG ID | hsa:51156 |
|---|---|
| mmu:217847 | |
| rno:171154 |
| Swiss-Prot ID | ZPI_MOUSE |
|---|---|
| ZPI_HUMAN |
| Ensembl ID | ENSG00000140093 |
|---|---|
| ENSP00000261994 | |
| ENST00000261994 | |
| ENSP00000376809 | |
| ENST00000393096 | |
| ENSMUSG00000061947 | |
| ENSMUSP00000048357 | |
| ENSMUST00000044231 | |
| ENSRNOG00000050761 | |
| ENSRNOP00000064104 | |
| ENSRNOT00000073709 |
| Homologene ID | 9414 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 2667725 |
|---|
| RGD ID | 621220 |
|---|
| MedScan ID | 51156 |
|---|