| Name | Tkt |
|---|---|
| Description | transketolase (Wernicke-Korsakoff syndrome) |
| Notes | human homolog is a key enzyme in the pentose-phosphate pathway and may be associated with Wernicke-Korsakoff syndrome [RGD] |
| Owner | Public |
| URN | urn:agi-llid:7086 |
| Connectivity | 104 |
| LocusLink ID | 7086 |
|---|---|
| 21881 | |
| 64524 |
| OMIM ID | 606781 |
|---|---|
| 277730 |
| GO ID | 0005509 |
|---|---|
| 0005515 | |
| 0016740 | |
| 0004802 | |
| 0008152 | |
| 0040008 | |
| 0003824 | |
| 0046872 | |
| 0000287 | |
| 0048029 | |
| 0005529 | |
| 0030976 | |
| 0006098 | |
| 0009052 | |
| 0046390 | |
| 0005789 | |
| 0005792 | |
| 0005777 | |
| 0005625 |
| Hugo ID | 11834 |
|---|
| Human chromosome position | 3p14.3 |
|---|
| Unigene ID | Hs.89643 |
|---|---|
| Mm.290692 | |
| Rn.5950 |
| KEGG ID | hsa:7086 |
|---|---|
| mmu:21881 | |
| rno:64524 |
| Alias | TKT1 |
|---|---|
| FLJ34765 | |
| transketolase | |
| p68 | |
| transketolase (Wernicke-Korsakoff syndrome) | |
| TKT I | |
| P(68) | |
| TKT |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Mouse chromosome position | 14 B1 |
|---|
| Rat chromosome position | 16p16 |
|---|
| Cell Localization | Cytoplasm |
|---|
| Homologene ID | 68154 |
|---|
| Pathway | pentose phosphate pathway |
|---|
| MGI ID | 105992 |
|---|
| Ariadne Ontology | Pentose-phosphate shunt |
|---|
| RGD ID | 621036 |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| protein binding | |
| sugar binding | |
| monosaccharide binding | |
| thiamin pyrophosphate binding | |
| metal ion binding | |
| calcium ion binding | |
| magnesium ion binding | |
| transferase activity | |
| transketolase activity |
| GO Cellular Component | soluble fraction |
|---|---|
| microsome | |
| endoplasmic reticulum membrane | |
| peroxisome |
| GO Biological Process | metabolic process |
|---|---|
| regulation of growth | |
| ribose phosphate biosynthetic process | |
| pentose-phosphate shunt | |
| pentose-phosphate shunt, non-oxidative branch |
| Group | soluble fraction |
|---|---|
| microsome | |
| endoplasmic reticulum membrane | |
| peroxisome | |
| catalytic activity | |
| protein binding | |
| sugar binding | |
| monosaccharide binding | |
| thiamin pyrophosphate binding | |
| metal ion binding | |
| calcium ion binding | |
| magnesium ion binding | |
| transferase activity | |
| transketolase activity | |
| metabolic process | |
| regulation of growth | |
| ribose phosphate biosynthetic process | |
| pentose-phosphate shunt | |
| pentose-phosphate shunt, non-oxidative branch | |
| Pentose-phosphate shunt |