| Name | Taldo1 |
|---|---|
| Description | transaldolase 1 |
| Notes | Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. |
| Owner | Public |
| URN | urn:agi-llid:6888 |
| Connectivity | 98 |
| LocusLink ID | 6888 |
|---|---|
| 21351 | |
| 83688 |
| OMIM ID | 602063 |
|---|---|
| 606003 |
| GO ID | 0005515 |
|---|---|
| 0004801 | |
| 0016740 | |
| 0005975 | |
| 0008152 | |
| 0006098 | |
| 0005737 | |
| 0003824 | |
| 0003674 | |
| 0048029 | |
| 0005529 | |
| 0008150 | |
| 0006002 | |
| 0019682 | |
| 0009052 | |
| 0005575 | |
| 0005829 | |
| 0005792 | |
| 0005625 |
| Hugo ID | 11559 |
|---|
| Human chromosome position | 11p15.5-p15.4 |
|---|
| Unigene ID | Hs.438678 |
|---|---|
| Mm.29182 | |
| Rn.3136 |
| KEGG ID | hsa:6888 |
|---|---|
| mmu:21351 | |
| rno:83688 |
| Alias | TAL |
|---|---|
| TALH | |
| TAL-H | |
| TALDOR | |
| transaldolase 1 | |
| glycerone transferase | |
| dihydroxyacetone transferase | |
| TALDO1 | |
| TALDO Is | |
| TALDO1s | |
| TALDO | |
| Transaldolase | |
| dihydroxyacetonetransferase | |
| transaldolases | |
| Transketolases | |
| transaldolase I | |
| transaldolase (Cricetulus griseus) | |
| dihydroxyacetonetransferases | |
| TALDO I | |
| TAL(H) | |
| TAL H |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Mouse chromosome position | 7 F3-F4 |
|---|
| Rat chromosome position | 1q41 |
|---|
| Cell Localization | Cytoplasm |
|---|
| Homologene ID | 4916 |
|---|
| Pathway | pentose phosphate pathway |
|---|
| MGI ID | 1274789 |
|---|
| Ariadne Ontology | Pentose-phosphate shunt |
|---|
| RGD ID | 620674 |
|---|
| GO Molecular Function | molecular_function |
|---|---|
| catalytic activity | |
| protein binding | |
| sugar binding | |
| monosaccharide binding | |
| transferase activity | |
| transaldolase activity |
| GO Cellular Component | cellular_component |
|---|---|
| soluble fraction | |
| microsome | |
| cytoplasm | |
| cytosol |
| GO Biological Process | biological_process |
|---|---|
| metabolic process | |
| pentose-phosphate shunt | |
| pentose-phosphate shunt, non-oxidative branch | |
| fructose 6-phosphate metabolic process | |
| glyceraldehyde-3-phosphate metabolic process | |
| carbohydrate metabolic process |
| Group | cellular_component |
|---|---|
| soluble fraction | |
| microsome | |
| cytoplasm | |
| cytosol | |
| molecular_function | |
| catalytic activity | |
| protein binding | |
| sugar binding | |
| monosaccharide binding | |
| transferase activity | |
| transaldolase activity | |
| biological_process | |
| metabolic process | |
| pentose-phosphate shunt | |
| pentose-phosphate shunt, non-oxidative branch | |
| fructose 6-phosphate metabolic process | |
| glyceraldehyde-3-phosphate metabolic process | |
| carbohydrate metabolic process | |
| Pentose-phosphate shunt |