| URN | urn:agi-llid:111 |
|---|---|
| Total Entities | 0 |
| Connectivity | 228 |
| Name | Adcy5 |
| Description | adenylate cyclase 5 |
| Notes | ADCY5 belongs to the adenylate cyclase (EC 4.6.1.1) family of enzymes responsible for the synthesis of cAMP (Ludwig and Seuwen, 2002 [PubMed 12503609]).[supplied by OMIM] |
| GO Molecular Function | adenylate cyclase activity |
|---|---|
| calcium- and calmodulin-responsive adenylate cyclase activity | |
| lyase activity | |
| phosphorus-oxygen lyase activity | |
| adenylate cyclase binding | |
| protein heterodimerization activity | |
| nucleotide binding | |
| ATP binding | |
| metal ion binding |
| GO Cellular Component | membrane |
|---|---|
| membrane raft | |
| integral component of membrane | |
| plasma membrane | |
| cell projection | |
| endosome | |
| cilium | |
| primary cilium | |
| sarcolemma |
| GO Biological Process | innate immune response |
|---|---|
| small molecule metabolic process | |
| cyclic nucleotide biosynthetic process | |
| cAMP biosynthetic process | |
| energy reserve metabolic process | |
| neuromuscular process controlling balance | |
| transmembrane transport | |
| signal transduction | |
| intracellular signal transduction | |
| adenosine receptor signaling pathway | |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway | |
| adenylate cyclase-activating dopamine receptor signaling pathway | |
| adenylate cyclase-activating G-protein coupled receptor signaling pathway | |
| adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| synaptic transmission | |
| water transport | |
| cellular response to glucagon stimulus | |
| locomotory behavior | |
| activation of protein kinase A activity | |
| activation of phospholipase C activity |
| Pathway | Cardiovascular Effects of Hyperthyroidism |
|---|---|
| dopamine signaling pathway | |
| glucagon signaling pathway |
| Group | ADCY |
|---|---|
| innate immune response | |
| small molecule metabolic process | |
| cyclic nucleotide biosynthetic process | |
| cAMP biosynthetic process | |
| adenylate cyclase activity | |
| calcium- and calmodulin-responsive adenylate cyclase activity | |
| energy reserve metabolic process | |
| neuromuscular process controlling balance | |
| transmembrane transport | |
| signal transduction | |
| intracellular signal transduction | |
| adenosine receptor signaling pathway | |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway | |
| adenylate cyclase-activating dopamine receptor signaling pathway | |
| adenylate cyclase-activating G-protein coupled receptor signaling pathway | |
| adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| synaptic transmission | |
| water transport | |
| cellular response to glucagon stimulus | |
| locomotory behavior | |
| activation of protein kinase A activity | |
| activation of phospholipase C activity | |
| lyase activity | |
| phosphorus-oxygen lyase activity | |
| adenylate cyclase binding | |
| protein heterodimerization activity | |
| nucleotide binding | |
| ATP binding | |
| metal ion binding | |
| membrane | |
| membrane raft | |
| integral component of membrane | |
| plasma membrane | |
| cell projection | |
| endosome | |
| cilium | |
| primary cilium | |
| sarcolemma | |
| Secreted proteins |
| LocusLink ID | 111 |
|---|---|
| 224129 | |
| 64532 |
| Cell Localization | Cytoplasm |
|---|---|
| Membrane | |
| Cell projection | |
| Cilium |
| GO ID | 0005524 |
|---|---|
| 0004016 | |
| 0008179 | |
| 0046872 | |
| 0046982 | |
| 0007202 | |
| 0034199 | |
| 0001973 | |
| 0007189 | |
| 0007191 | |
| 0007193 | |
| 0007195 | |
| 0071377 | |
| 0006112 | |
| 0007173 | |
| 0008543 | |
| 0045087 | |
| 0035556 | |
| 0007626 | |
| 0050885 | |
| 0048011 | |
| 0007165 | |
| 0044281 | |
| 0007268 | |
| 0055085 | |
| 0006833 | |
| 0016021 | |
| 0005886 | |
| 0072372 | |
| 0008294 | |
| 0016829 | |
| 0000166 | |
| 0016849 | |
| 0006171 | |
| 0009190 | |
| 0042995 | |
| 0005929 | |
| 0005768 | |
| 0016020 | |
| 0045121 | |
| 0042383 | |
| 0000287 | |
| 0007242 | |
| 0044424 | |
| 0005624 |
| Alias | AC5 |
|---|---|
| FDFM | |
| adenylate cyclase type 5 | |
| adenylyl cyclase 5 | |
| adenylate cyclase type V | |
| ATP pyrophosphate-lyase 5 | |
| AW121902 | |
| adenylyl cyclase type V | |
| LOC255218 | |
| OTTHUMP00000215643 | |
| OTTHUMP00000215641 | |
| LOC224129 | |
| OTTHUMP00000215642 | |
| Adenylate cyclase, type V | |
| adenylate cyclase 5 | |
| ADCY5 | |
| hypothetical protein LOC224129 | |
| expressed sequence AW121902 | |
| AC 5 | |
| AC-5 | |
| AC(5) |
| Mouse chromosome position | 16 |
|---|---|
| 16 B-5 |
| OMIM ID | 600293 |
|---|---|
| 606703 |
| Rat chromosome position | 11q22 |
|---|
| Hugo ID | 236 |
|---|
| Human chromosome position | 3q21.1 |
|---|---|
| 3q13.2-q21 |
| Swiss-Prot Accession | O95622 |
|---|---|
| B7Z2C7 | |
| B3KWA8 | |
| P84309 | |
| Q04400 | |
| Q3TU67 | |
| Q3UH09 | |
| Q5BL06 | |
| B7Z8A6 | |
| Q7RTV7 | |
| Q8NFM3 |
| Unigene ID | Hs.593292 |
|---|---|
| Mm.41137 | |
| Rn.6278 | |
| Hs.593293 | |
| Hs.655144 |
| KEGG ID | hsa:111 |
|---|---|
| mmu:224129 | |
| rno:64532 |
| Swiss-Prot ID | ADCY5_MOUSE |
|---|---|
| ADCY5_RAT | |
| ADCY5_HUMAN |
| EC Number | 4.6.1.1 |
|---|
| Ensembl ID | ENSG00000173175 |
|---|---|
| ENSP00000419361 | |
| ENST00000462833 | |
| ENSRNOG00000002229 | |
| ENSRNOP00000046488 | |
| ENSRNOT00000049180 |
| Homologene ID | 11213 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 99673 |
|---|
| RGD ID | 71014 |
|---|
| MedScan ID | 111 |
|---|