| URN | urn:agi-Regulation:inout-urn:agi-llid:2890:out-urn:agi-gocellproc:0007268::unknown |
|---|---|
| References | 12 |
| Connectivity | 2 |
| Effect | unknown |
| Original # of References | 7 |
| TextRef | info:pmid/9952404#body:190 |
|---|---|
| PubYear | 1999 |
| MedlineTA | J Neurosci |
| Organ | Dendrites |
| MedLine Reference | 9952404:1189 |
| Sentence | The rapid redistribution of GluR1 subunits away from the synapse would be expected to have significant effects on synaptic transmission. |
| CellType | Neurons |
| TextRef | info:pmid/11404432#body:299 |
|---|---|
| PubYear | 2001 |
| MedlineTA | J Neurosci |
| MedLine Reference | 11404432:1298 |
| Sentence | However, for the interpretation of the present results, this factor is not essential, because we had another mouse line with impaired GluR-A subunit-mediated synaptic transmission. |
| CellType | Neurons |
| TextRef | info:pmid/17928436#body:60 |
|---|---|
| PubYear | 2007 |
| MedlineTA | J Neurosci |
| Organ | Amygdaloid |
| MedLine Reference | 17928436:1059 |
| Sentence | Although our study reveals pathway-specific involvements of GluR1- and GluR3-dependent mechanisms to glutamatergic synaptic transmission and plasticity, the former appears to dominate during auditory and contextual fear conditioning. |
| TextRef | info:pmid/17670991#body:47 |
|---|---|
| PubYear | 2007 |
| MedlineTA | J Neurosci |
| Organ | Brain |
| MedLine Reference | 17670991:1046 |
| Sentence | Introduction Top Abstract Introduction Materials and Methods Results Discussion References Homomeric and heteromeric AMPA receptor channels are tetramers of the subunits GluR1-4 (Dingledine et al., 1999[Go]) that mediate the majority of fast excitatory synaptic transmission in the mammalian CNS. |
| TextRef | info:pmid/18632948#body:227 |
|---|---|
| PubYear | 2008 |
| MedlineTA | J Neurosci |
| Organ | cingulate cortex |
| MedLine Reference | 18632948:1226 |
| Sentence | anterior cingulate cortex AMPA receptor and allodynia We have shown that peripheral nerve injury caused increased distribution of GluR1 and AMPA receptor-mediated synaptic transmission in the anterior cingulate cortex. |
| TextMods | 0: 'ACC ' -> 'anterior cingulate cortex ' 192: 'ACC' -> 'anterior cingulate cortex' |
| TextRef | info:pmid/15541312#body:49 |
|---|---|
| PubYear | 2004 |
| MedlineTA | Neuron |
| MedLine Reference | 15541312:1048 |
| Sentence | GluR-A and GluR-B serve as key substrates for activity-induced regulation of synaptic transmission via rapid and selective modifications in their phosphorylation status and binding to scaffolding proteins involved in membrane trafficking, which, in turn, determine their synaptic availability and function (Shi et al. 2001; Liu and Cull-Candy 2000; Malinow and Malenka 2002 and Lee et al. 2003). |
| CellType | Neurons |
| TextRef | info:pmid/19020030#body:484 |
|---|---|
| PubYear | 2008 |
| MedlineTA | J Neurosci |
| Organ | Dendrites |
| MedLine Reference | 19020030:1483 |
| Sentence | Although this approach led to the conclusion that Kalirin-7 regulates the GluR1 content of pyramidal neuron dendritic spines and AMPA receptor-mediated synaptic transmission (Xie et al., 2007[Go]), the GluR1 content of postsynaptic densities purified from Kalirin-7knock-out neurons is indistinguishable from wild-type. |
| CellType | Pyramidal Cells |
| TextMods | 50: 'Kal7 ' -> 'Kalirin-7 ' 219: 'PSDs ' -> 'postsynaptic densities ' 256: 'Kal7' -> 'Kalirin-7' 265: 'KO ' -> 'knock-out ' |
| TextRef | info:pmid/11404432#cont:261 |
|---|---|
| MedLine Reference | 11404432:10260 |
| Sentence | However, for the interpretation of the present results, this factor is not essential, because we had another mouse line with impaired GluR-A subunit-mediated synaptic transmission. |
| CellType | neural |
| Journal | J. Neurosci |
| Journal Reference | v21 i12 p4451 |
| Journal Link | http://www.jneurosci.org/cgi/content/full/21/12/4451 |
| TextRef | info:pmid/15743906#cont:300 |
|---|---|
| Organ | hippocampal |
| MedLine Reference | 15743906:10299 |
| Sentence | Finally, in contrast to the spinophilin/PP1 complex, which down-regulates AMPAR (Feng et al., 2000 ), our studies suggest the NrbI-bound PP1 facilitates increased synaptic targeting of GluR1 and AMPAR-mediated synaptic transmission. |
| Journal | Mol. Biol. Cell |
| Journal Reference | v16 i5 p2349 |
| Journal Link | http://www.molbiolcell.org/cgi/content/full/16/5/2349 |
| TextRef | info:pmid/15805114#cont:22 |
|---|---|
| MedLine Reference | 15805114:10021 |
| Sentence | INTRODUCTION TOP ABSTRACT INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION REFERENCES Ionotropic glutamatergic synaptic transmission is mediated by the N- methyl- D -aspartate, AMPA, 1 and kainate-type glutamate receptors (KARs). |
| Tissue | Plasma |
| Journal | J. Biol. Chem |
| Journal Reference | v280 i24 p22968 |
| Journal Link | http://www.jbc.org/cgi/content/full/280/24/22968 |
| TextRef | info:pmid/17670991#cont:12 |
|---|---|
| Organ | Brain |
| MedLine Reference | 17670991:10011 |
| Sentence | Key words: glutamate receptor; AMPA receptor; TARP; stargazin ; ?4; desensitization Introduction Top Abstract Introduction Materials and Methods Results Discussion References Homomeric and heteromeric AMPA receptor channels are tetramers of the subunits GluR1-4 (Dingledine et al., 1999 ) that mediate the majority of fast excitatory synaptic transmission in the mammalian CNS. |
| Journal | J. Neurosci |
| Journal Reference | v27 i31 p8442 |
| Journal Link | http://www.jneurosci.org/cgi/content/full/27/31/8442 |
| MedLine Reference | 164103037:10020 |
|---|---|
| Sentence | GluR-A and GluR-B serve as key substrates for activity-induced regulation of synaptic transmission via rapid and selective modifications in their phosphorylation status and binding to scaffolding proteins involved in membrane trafficking, which, in turn, determine their synaptic availability and function ( Shi et al. 2001 ; Liu and Cull-Candy 2000 ; Malinow and Malenka 2002 and Lee et al. 2003 ). |
| CellType | neural |
| Tissue | glia |
| Journal | Neuron |
| Journal Reference | v44 i4 p9 |
| Journal Link | http://www.neuron.org/content/article/fulltext?uid=PIIS0896627304006853 |