| URN | urn:agi-llid:707 |
|---|---|
| Total Entities | 0 |
| Connectivity | 3799 |
| Name | Pten |
| Description | phosphatase and tensin homolog |
| Notes | may be involved in regulation of phosphoinositide 3-kinase and Akt kinase mediated antiapoptotic pathways [RGD] |
| GO Molecular Function | hydrolase activity |
|---|---|
| phosphatase activity | |
| phosphoprotein phosphatase activity | |
| inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | |
| protein tyrosine phosphatase activity | |
| protein serine-threonine phosphatase activity | |
| protein tyrosine-serine-threonine phosphatase activity | |
| phosphatidylinositol-3-phosphatase activity | |
| phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | |
| lipid binding | |
| enzyme binding | |
| anaphase-promoting complex binding | |
| platelet-derived growth factor receptor binding | |
| protein kinase binding | |
| PDZ domain binding | |
| magnesium ion binding |
| GO Cellular Component | cytoplasmic side of plasma membrane |
|---|---|
| postsynaptic membrane | |
| PML body | |
| myelin sheath adaxonal region | |
| Schmidt-Lanterman incisure | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| mitochondrion | |
| nucleus | |
| dendritic spine | |
| neuron projection |
| GO Biological Process | male mating behavior |
|---|---|
| prostate gland growth | |
| maternal behavior | |
| T cell receptor signaling pathway | |
| innate immune response | |
| Fc-epsilon receptor signaling pathway | |
| cell proliferation | |
| lipid metabolic process | |
| small molecule metabolic process | |
| phosphatidylinositol biosynthetic process | |
| inositol phosphate dephosphorylation | |
| phospholipid metabolic process | |
| phosphatidylinositol dephosphorylation | |
| inositol phosphate metabolic process | |
| multicellular organismal response to stress | |
| negative regulation of organ growth | |
| negative regulation of myelination | |
| prepulse inhibition | |
| learning or memory | |
| memory | |
| central nervous system myelin maintenance | |
| central nervous system development | |
| nervous system development | |
| angiogenesis | |
| heart development | |
| cardiac muscle tissue development | |
| brain morphogenesis | |
| forebrain morphogenesis | |
| dentate gyrus development | |
| synapse assembly | |
| synapse maturation | |
| presynaptic membrane assembly | |
| postsynaptic density assembly | |
| central nervous system neuron axonogenesis | |
| negative regulation of axonogenesis | |
| regulation of neuron projection development | |
| negative regulation of dendritic spine morphogenesis | |
| neuron projection development | |
| dendritic spine morphogenesis | |
| endothelial cell migration | |
| aging | |
| negative regulation of cell aging | |
| locomotor rhythm | |
| regulation of cellular component size | |
| activation of mitotic anaphase-promoting complex activity | |
| negative regulation of G1-S transition of mitotic cell cycle | |
| negative regulation of cyclin-dependent protein serine-threonine kinase activity involved in G1-S transition of mitotic cell cycle | |
| regulation of cell cycle | |
| regulation of cyclin-dependent protein serine-threonine kinase activity | |
| protein kinase B signaling | |
| negative regulation of protein kinase B signaling | |
| negative regulation of phosphatidylinositol 3-kinase signaling | |
| phosphatidylinositol-mediated signaling | |
| positive regulation of apoptotic signaling pathway | |
| canonical Wnt signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| platelet-derived growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| neuron-neuron synaptic transmission | |
| long-term synaptic potentiation | |
| rhythmic synaptic transmission | |
| long term synaptic depression | |
| positive regulation of excitatory postsynaptic membrane potential | |
| negative regulation of excitatory postsynaptic membrane potential | |
| negative regulation of focal adhesion assembly | |
| cell migration | |
| negative regulation of cell migration | |
| apoptotic process | |
| positive regulation of apoptotic process | |
| negative regulation of apoptotic process | |
| regulation of myeloid cell apoptotic process | |
| regulation of B cell apoptotic process | |
| negative regulation of cell size | |
| positive regulation of cell proliferation | |
| negative regulation of cell proliferation | |
| negative regulation of epithelial cell proliferation | |
| negative regulation of synaptic vesicle clustering | |
| negative regulation of phagocytosis | |
| response to inorganic substance | |
| response to drug | |
| response to organic substance | |
| response to nutrient | |
| response to arsenic-containing substance | |
| response to ATP | |
| response to glucose | |
| response to estradiol | |
| response to ethanol | |
| response to zinc ion | |
| response to organic cyclic compound | |
| locomotory behavior | |
| social behavior | |
| positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| negative regulation of ribosome biogenesis | |
| negative regulation of protein phosphorylation | |
| positive regulation of sequence-specific DNA binding transcription factor activity | |
| regulation of protein stability | |
| protein stabilization | |
| protein dephosphorylation | |
| peptidyl-tyrosine dephosphorylation | |
| dephosphorylation |
| Pathway | Tight Junction Assembly (Occludin) |
|---|---|
| Adherens Junction Assembly (Cadherins) | |
| Androgen Receptor to NKX-3.1 Signaling in Prostate Cancer | |
| Androgen Receptor to Akt Signaling in Prostate Cancer | |
| Prostate Cancer Overview | |
| Metastatic Colorectal Cancer Overview | |
| Dystrophin Glycoprotein Complex Signaling in Duchenne Muscular Dystrophy | |
| Duchenne Muscular Dystrophy Overview | |
| IGF1 in Muscle Hypertrophy | |
| Mechanism of Cetuximab Resistance in Colorectal Cancer | |
| Osteoclast Activation in Multiple Myeloma | |
| Proteins Involved in Pathogenesis of Acute Myeloid Leukemia | |
| Proteins Involved in Pathogenesis of T-cell Acute Lymphoblastic Leukemia | |
| T-cell Acute Lymphoblastic Leukemia Overview | |
| Diffuse Large-B-cell Lymphoma, GCB Subtype | |
| Diffuse Large-B-cell Lymphoma Overview | |
| Cowden Syndrome | |
| Mantle Cell Lymphoma Overview | |
| PI3K/AKT/MTOR, NF-kB and BCR Signaling Deregulation in Mantle Cell Lymphoma | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to ERBB2/VEGFR/Akt Signaling Pathway | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to IGF1R/Akt Signaling Pathway | |
| Proteins Involved in Pathogenesis of Breast Cancer Related to ESR1 Signaling Pathway | |
| ESR1/ERBB-positive Luminal Breast Cancer | |
| Basal Breast Cancer | |
| Insulin Influence on Glycogenesis | |
| Insulin Influence on Protein Synthesis | |
| Proteins Involved in Pathogenesis of Insulin Resistance | |
| Proteins Involved in Pathogenesis of Diabetes Mellitus Type 2 | |
| Clear Cell Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Clear Cell Ovarian Carcinoma | |
| Mucinous Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Mucinous Ovarian Carcinoma | |
| Endometrioid Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Endometrioid Ovarian Carcinoma | |
| Ovarian Cancer Overview | |
| Low-grade Serous Ovarian Carcinoma | |
| Proteins Involved in Pathogenesis of Low-grade Serous Ovarian Carcinoma | |
| Type I Endometrial Cancer (Endometrioid Endometrial Cancer) | |
| Proteins Involved in Pathogenesis of Endometrial Cancer | |
| Endometrial Cancer Overview | |
| Deregulation of Cell Cycle in Melanoma | |
| Block of Apoptosis in Melanoma | |
| Proteins Involved in Pathogenesis of Melanoma | |
| Melanoma Overview | |
| Proteins Involved in Pathogenesis of Prostate Cancer | |
| T-cell Positive Selection and Neglect-Induced Death | |
| Cancer Overview | |
| Proteins Involved in Pathogenesis of Pulmonary Hypertension | |
| Primary Glioblastoma | |
| Secondary Glioblastoma | |
| Proteins Involved in Pathogenesis of Glioblastoma | |
| Mesenchymal Subtype of Glioblastoma | |
| Proteins Involved in Pathogenesis of Glioma | |
| Proteins Involved in Pathogenesis of Astrocytoma | |
| Proteins Involved in Pathogenesis of Neuroblastoma | |
| Growth Factor Signaling in Pancreatic Cancer | |
| STK11 Signaling in Pancreatic Cancer | |
| Pancreatic Ductal Carcinoma | |
| Proteins Involved in Pathogenesis of Pancreatic Cancer | |
| Peutz-Jeghers Syndrome Overview | |
| Growth Factor Signaling in Hepatocellular Carcinoma | |
| Proteins Involved in Pathogenesis of Hepatocellular Carcinoma | |
| Hepatocellular Carcinoma Overview | |
| Proteins Involved in Pathogenesis of Epilepsy | |
| Proteins Involved in Pathogenesis of Myocardial Ischemia | |
| Preconditioning Ischemia | |
| Tamoxifen-Induced Endometrial Cancer | |
| TGFB1-TGFBR2 Expression Targets | |
| NGF/AP-1/TP53/MYC Expression Targets | |
| NGF/SMAD3/NF-kB Expression Targets | |
| IFNG-IFNR Expression Targets | |
| PDCD1/NF-kB Expression Targets | |
| PDCD1/AP-1 Expression Targets | |
| Insulin/ELK-SRF/HIF1A/MYC/SREBF Expression Targets | |
| Insulin/STAT Expression Targets | |
| Insulin/CEBPA/CTNNB/FOXA/FOXO Expression Targets | |
| Insulin/MEF/MYOD Expression Targets | |
| PDGF/AP-1/CREB/CREBBP/MYC Expression Targets | |
| PDGF/STAT Expression Targets | |
| TGFB1-ACVRL1 Expression Targets | |
| TGFB1-TGFBR1/AP-1 Expression Targets | |
| non-small cell lung cancer pathway | |
| prostate cancer pathway | |
| pancreatic cancer pathway | |
| prostate cancer pathway | |
| endometrial cancer pathway | |
| phosphatidylinositol 3-kinase-Akt signaling pathway | |
| phosphatidylinositol 3-kinase-Akt signaling pathway | |
| nuclear factor, erythroid 2 like 2 signaling pathway | |
| phosphatidylinositol 3-kinase-Akt signaling pathway | |
| nuclear factor-erythoid 2 like 2 signaling pathway |
| Group | PTEN |
|---|---|
| Tumor suppressors | |
| male mating behavior | |
| prostate gland growth | |
| maternal behavior | |
| T cell receptor signaling pathway | |
| innate immune response | |
| Fc-epsilon receptor signaling pathway | |
| cell proliferation | |
| lipid metabolic process | |
| small molecule metabolic process | |
| phosphatidylinositol biosynthetic process | |
| inositol phosphate dephosphorylation | |
| phospholipid metabolic process | |
| phosphatidylinositol dephosphorylation | |
| inositol phosphate metabolic process | |
| multicellular organismal response to stress | |
| negative regulation of organ growth | |
| negative regulation of myelination | |
| prepulse inhibition | |
| learning or memory | |
| memory | |
| central nervous system myelin maintenance | |
| central nervous system development | |
| nervous system development | |
| angiogenesis | |
| heart development | |
| cardiac muscle tissue development | |
| brain morphogenesis | |
| forebrain morphogenesis | |
| dentate gyrus development | |
| synapse assembly | |
| synapse maturation | |
| presynaptic membrane assembly | |
| postsynaptic density assembly | |
| central nervous system neuron axonogenesis | |
| negative regulation of axonogenesis | |
| regulation of neuron projection development | |
| negative regulation of dendritic spine morphogenesis | |
| neuron projection development | |
| dendritic spine morphogenesis | |
| endothelial cell migration | |
| aging | |
| negative regulation of cell aging | |
| locomotor rhythm | |
| regulation of cellular component size | |
| activation of mitotic anaphase-promoting complex activity | |
| negative regulation of G1-S transition of mitotic cell cycle | |
| negative regulation of cyclin-dependent protein serine-threonine kinase activity involved in G1-S transition of mitotic cell cycle | |
| regulation of cell cycle | |
| regulation of cyclin-dependent protein serine-threonine kinase activity | |
| protein kinase B signaling | |
| negative regulation of protein kinase B signaling | |
| negative regulation of phosphatidylinositol 3-kinase signaling | |
| phosphatidylinositol-mediated signaling | |
| positive regulation of apoptotic signaling pathway | |
| canonical Wnt signaling pathway | |
| neurotrophin TRK receptor signaling pathway | |
| fibroblast growth factor receptor signaling pathway | |
| platelet-derived growth factor receptor signaling pathway | |
| epidermal growth factor receptor signaling pathway | |
| neuron-neuron synaptic transmission | |
| long-term synaptic potentiation | |
| rhythmic synaptic transmission | |
| long term synaptic depression | |
| positive regulation of excitatory postsynaptic membrane potential | |
| negative regulation of excitatory postsynaptic membrane potential | |
| negative regulation of focal adhesion assembly | |
| cell migration | |
| negative regulation of cell migration | |
| apoptotic process | |
| positive regulation of apoptotic process | |
| negative regulation of apoptotic process | |
| regulation of myeloid cell apoptotic process | |
| regulation of B cell apoptotic process | |
| negative regulation of cell size | |
| positive regulation of cell proliferation | |
| negative regulation of cell proliferation | |
| negative regulation of epithelial cell proliferation | |
| negative regulation of synaptic vesicle clustering | |
| negative regulation of phagocytosis | |
| response to inorganic substance | |
| response to drug | |
| response to organic substance | |
| response to nutrient | |
| response to arsenic-containing substance | |
| response to ATP | |
| response to glucose | |
| response to estradiol | |
| response to ethanol | |
| response to zinc ion | |
| response to organic cyclic compound | |
| locomotory behavior | |
| social behavior | |
| positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| negative regulation of ribosome biogenesis | |
| negative regulation of protein phosphorylation | |
| positive regulation of sequence-specific DNA binding transcription factor activity | |
| regulation of protein stability | |
| protein stabilization | |
| hydrolase activity | |
| phosphatase activity | |
| phosphoprotein phosphatase activity | |
| inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | |
| protein tyrosine phosphatase activity | |
| protein serine-threonine phosphatase activity | |
| protein tyrosine-serine-threonine phosphatase activity | |
| phosphatidylinositol-3-phosphatase activity | |
| phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | |
| protein dephosphorylation | |
| peptidyl-tyrosine dephosphorylation | |
| dephosphorylation | |
| lipid binding | |
| enzyme binding | |
| anaphase-promoting complex binding | |
| platelet-derived growth factor receptor binding | |
| protein kinase binding | |
| PDZ domain binding | |
| magnesium ion binding | |
| cytoplasmic side of plasma membrane | |
| postsynaptic membrane | |
| PML body | |
| myelin sheath adaxonal region | |
| Schmidt-Lanterman incisure | |
| intracellular | |
| plasma membrane | |
| cell projection | |
| cytoplasm | |
| cytosol | |
| mitochondrion | |
| nucleus | |
| dendritic spine | |
| neuron projection | |
| Genes with Mutations Associated with T-cell Acute Lymphoblastic Luekemia | |
| Proteins Involved in Pathogenesis of B-cell Acute Lymphoblastic Leukemia | |
| Genes with Mutations Associated with Diffuse Large-B-cell Lymphoma, GCB Subtype | |
| Genes with Mutations Associated with Cowden Syndrome | |
| Genes with Mutations Associated with Breast Cancer | |
| Genes with Mutations Associated with Ovarian Cancer | |
| Genes with Mutations Associated with Endometrial Cancer | |
| Genes with Mutations Associated with Melanoma | |
| Genes Hypermethylated in Melanoma | |
| Proteins Involved in Pathogenesis of Cowden Syndrome | |
| Proteins Involved in Pathogenesis of Li-Fraumeni Syndrome | |
| Genes with Mutations Associated with Prostate Cancer | |
| Genes with Mutations Associated with Hepatocellular Carcinoma | |
| Disease Genes Identified in Epilepsy with Mental Retardation and Brain Malformations | |
| Genes with Mutations, Deletions, and Amplifications Associated with Primary Glioblastoma | |
| Genes with Mutations, Deletions, and Amplifications Associated with Secondary Glioblastoma | |
| Genes with Mutations, Deletions, and Amplifications Associated with Glioma | |
| Genes with Mutations Associated with Pancreatic Cancer | |
| Secreted proteins | |
| Biofluids assayable substances |
| Source | Curated |
|---|---|
| GO component | |
| ResNet |
| LocusLink ID | 707 |
|---|---|
| 5728 | |
| 19211 | |
| 50557 | |
| 4260 | |
| 70161 | |
| 107201 | |
| 29420 | |
| 368415 | |
| 322802 | |
| 325503 | |
| 327192 | |
| 334970 | |
| 335216 |
| Cell Localization | Cytoplasm |
|---|---|
| Nucleus | |
| PML body |
| GO ID | 0030165 |
|---|---|
| 0010997 | |
| 0019899 | |
| 0051717 | |
| 0008289 | |
| 0000287 | |
| 0016314 | |
| 0051800 | |
| 0004438 | |
| 0004721 | |
| 0019901 | |
| 0004722 | |
| 0004725 | |
| 0008138 | |
| 0038095 | |
| 0050852 | |
| 0007092 | |
| 0001525 | |
| 0006915 | |
| 0048854 | |
| 0060070 | |
| 0048738 | |
| 0016477 | |
| 0008283 | |
| 0007417 | |
| 0032286 | |
| 0021955 | |
| 0060997 | |
| 0021542 | |
| 0043542 | |
| 0007173 | |
| 0008543 | |
| 0048853 | |
| 0007507 | |
| 0045087 | |
| 0046855 | |
| 0043647 | |
| 0007611 | |
| 0045475 | |
| 0007626 | |
| 0060291 | |
| 0060179 | |
| 0042711 | |
| 0033555 | |
| 2000134 | |
| 0043066 | |
| 0050771 | |
| 0090344 | |
| 0030336 | |
| 0008285 | |
| 0045792 | |
| 0031658 | |
| 0061002 | |
| 0050680 | |
| 0090394 | |
| 0051895 | |
| 0031642 | |
| 0046621 | |
| 0014067 | |
| 0051898 | |
| 0001933 | |
| 0090071 | |
| 2000808 | |
| 0007270 | |
| 0048011 | |
| 0035335 | |
| 0006661 | |
| 0046856 | |
| 0048015 | |
| 0006644 | |
| 0008284 | |
| 2000463 | |
| 2000060 | |
| 0051091 | |
| 0097107 | |
| 0060134 | |
| 0097105 | |
| 0060736 | |
| 0006470 | |
| 0043491 | |
| 0050821 | |
| 0002902 | |
| 0032535 | |
| 0000079 | |
| 0033032 | |
| 0010975 | |
| 0031647 | |
| 0060024 | |
| 0044281 | |
| 0035176 | |
| 0007416 | |
| 0060074 | |
| 0016605 | |
| 0043220 | |
| 0042995 | |
| 0005737 | |
| 0009898 | |
| 0005829 | |
| 0035749 | |
| 0043005 | |
| 0005634 | |
| 0005886 | |
| 0016787 | |
| 0016791 | |
| 0005161 | |
| 0016311 | |
| 0006629 | |
| 0060292 | |
| 0007613 | |
| 0050765 | |
| 0007399 | |
| 0031175 | |
| 0048008 | |
| 0043065 | |
| 2001235 | |
| 0051726 | |
| 0043197 | |
| 0005622 | |
| 0005739 | |
| 0045211 | |
| 0007568 | |
| 0033198 | |
| 0046685 | |
| 0042493 | |
| 0032355 | |
| 0045471 | |
| 0009749 | |
| 0010035 | |
| 0007584 | |
| 0014070 | |
| 0010033 | |
| 0010043 | |
| 0006917 | |
| 0004437 | |
| 0005515 | |
| 0045786 | |
| 0007049 | |
| 0001568 | |
| 0031174 | |
| 0042577 | |
| 0051896 |
| Alias | BZS |
|---|---|
| DEC | |
| CWS1 | |
| GLM2 | |
| MHAM | |
| TEP1 | |
| MMAC1 | |
| PTEN1 | |
| 10q23del | |
| phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | |
| phosphatase and tensin-like protein | |
| mutated in multiple advanced cancers 1 | |
| MMAC1 phosphatase and tensin homolog deleted on chromosome 10 | |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | |
| AI463227 | |
| 2310035O07Rik | |
| A130070J02Rik | |
| B430203M17Rik | |
| Mmac | |
| protein tyrosine phosphatase and tensin-like protein | |
| phosphatase and tensin homolog deleted on chromosome ten | |
| PTEN I | |
| PTEN | |
| TEP I | |
| tensin homolog | |
| Protein-tyrosine phosphatase PTEN | |
| phosphatase and tensin-like | |
| PTEN/MMAC1 | |
| RIKEN cDNA 2310035O07 gene | |
| PTEN/MMAC1/TEP1 | |
| PTEN/MMAC1/TEP | |
| MMAC1/PTEN | |
| tumor suppressor PTEN | |
| Bannayan-Zonana syndrome protein | |
| Bannayan-Zonana syndrome gene | |
| phosphatase and tensin homologue deleted on chromosome 10 | |
| RIKEN cDNA B430203M17 gene | |
| OTTMUSP00000023423 | |
| phosphatase and tensin homolog deleted on chromosome 10 | |
| phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | |
| phosphatase and tensin homolog | |
| 2310035O07 | |
| B430203M17 | |
| Chromosome 10q23 deletion syndrome | |
| Deleted in endometrial carcinoma | |
| Mutated in multiple advanced cancers I | |
| A130070J02 | |
| OTTHUMP00000020032 | |
| MGC11227 | |
| multiple hamartoma protein | |
| multiple hamartoma gene | |
| MMAC I | |
| MGC183880 | |
| multiple hamartoma (Cowden syndrome) gene | |
| Mutated in multiple advanced cancers 1 | |
| Mutated in multiple advanced cancers I | |
| multiple hamartoma | |
| phosphatase and tensin homologue | |
| MMAC1 phosphatase and tension homolog deleted on chromosome 10 | |
| fb73f10 | |
| wu:fb73f10 | |
| fc83f12 | |
| wu:fc83f12 | |
| fd16b10 | |
| wu:fd16b10 | |
| fa11a08 | |
| wu:fa11a08 | |
| fk90e11 | |
| wu:fk90e11 | |
| MGC123112 | |
| chromosome | |
| phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) | |
| ptenb | |
| scaffold | |
| si:bz1g13.4 |
| Mouse chromosome position | 19 28.14 cM |
|---|---|
| 19 24.5 cM |
| OMIM ID | 601728 |
|---|---|
| 153480 | |
| 158350 | |
| 155600 | |
| 608089 | |
| 613028 | |
| 605309 | |
| 176807 | |
| 607174 | |
| 275355 | |
| 188470 | |
| 276950 | |
| 612359 | |
| 612242 | |
| 174900 | |
| 137800 | |
| 176920 |
| Rat chromosome position | 1q41-q43 |
|---|
| Hugo ID | 9588 |
|---|
| Human chromosome position | 10q23.3 |
|---|
| Swiss-Prot Accession | F6KD01 |
|---|---|
| P60484 | |
| O08586 | |
| Q3UUT8 | |
| O54857 | |
| B2R904 | |
| O00633 | |
| O02679 | |
| Q6ICT7 | |
| Q3UFB0 | |
| Q542G1 | |
| Q3UUN5 | |
| Q8BJP9 | |
| Q8BSR7 | |
| Q812B9 |
| Unigene ID | Hs.500466 |
|---|---|
| Mm.245395 | |
| Rn.22158 | |
| Mm.444861 | |
| Hs.592504 | |
| Mm.244179 | |
| Mm.393980 | |
| Mm.220979 | |
| Dr.140568 | |
| Mm.440799 |
| KEGG ID | hsa:5728 |
|---|---|
| mmu:19211 | |
| rno:50557 |
| Swiss-Prot ID | PTEN_HUMAN |
|---|---|
| PTEN_MOUSE | |
| O54857_RAT | |
| Q3UUT8_MOUSE | |
| B2R904_HUMAN | |
| Q8BJP9_MOUSE |
| EC Number | 3.1.3.67 |
|---|---|
| 3.1.3.16 | |
| 3.1.3.48 |
| Ensembl ID | ENSMUSG00000013663 |
|---|---|
| ENSMUSP00000013807 | |
| ENSMUST00000013807 | |
| ENSRNOG00000020723 | |
| ENSRNOP00000028143 | |
| ENSRNOT00000028143 |
| Homologene ID | 265 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus | |
| Danio rerio |
| MGI ID | 109583 |
|---|---|
| 1917411 | |
| 2147557 |
| RGD ID | 61995 |
|---|
| MedScan ID | 707 |
|---|---|
| 5728 |
| Primary Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00114410 |
|---|---|
| IPI00012587 | |
| IPI00199035 | |
| IPI00652977 | |
| IPI00222440 |
| KEGG pathway | Focal adhesion |
|---|---|
| Inositol phosphate metabolism | |
| Phosphatidylinositol signaling system | |
| Tight junction | |
| Glioma | |
| Melanoma | |
| Endometrial cancer | |
| Prostate cancer | |
| Small cell lung cancer |
| Homo sapiens Chromosome position | 10q23.3 |
|---|
| Microarray ID | 160614_at |
|---|---|
| 94988_at | |
| 94989_at | |
| 222176_at | |
| 233254_x_at | |
| 225363_at | |
| 1454722_at | |
| 1455728_at |
| FunctionalClass | PDZ domain binding |
|---|---|
| hydrolase | |
| inositol-1,3,4,5-tetrakisphosphate 3-phosphatase | |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase | |
| phosphatidylinositol-3,4-bisphosphate 3-phosphatase | |
| phosphatidylinositol-3-phosphatase | |
| protein binding | |
| protein serine/threonine phosphatase | |
| protein tyrosine phosphatase | |
| protein tyrosine/serine/threonine phosphatase | |
| phosphoprotein phosphatase | |
| inositol or phosphatidylinositol phosphatase | |
| platelet-derived growth factor receptor binding | |
| lipid binding | |
| lipid phosphatase | |
| phosphoric monoester hydrolase |
| Mus musculus Chromosome position | 19 24.5 cM |
|---|---|
| 19 C1 | |
| 19 |
| Danio rerio Chromosome position | LG 12 |
|---|