Protein Atrn

URN urn:agi-llid:8455
Connectivity 20
Name Atrn
Description attractin
Notes Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq]

Pathway melanocortin system pathway

GO Molecular Function sugar binding
receptor activity

GO Cellular Component extracellular region
membrane
extracellular space
plasma membrane
cytoplasm
integral to membrane
integral to plasma membrane

GO Biological Process pigmentation
regulation of multicellular organism growth
response to oxidative stress
inflammatory response

Ariadne Ontology Receptors

Group Receptors
extracellular region
pigmentation
regulation of multicellular organism growth
response to oxidative stress
inflammatory response
sugar binding
receptor activity
membrane
extracellular space
plasma membrane
cytoplasm
integral to membrane
integral to plasma membrane

MedScan ID 8455

Hugo ID 885

Human chromosome position 20p13

LocusLink ID 8455
11990
83526

Alias MGCA
DPPT-L
KIAA0548
MGC126754
attractin
attractin-2
mahogany homolog
mahogany protein
mg
AW558010
mahogany
mKIAA0548
RP23-228H14.1
protein mahogany
OTTMUSP00000016559
protein zitter
membrane attractin
ATRN
attractin II
gene mahogany
mahogany gene
OTTHUMP00000030102
OTTHUMP00000030103
with dipeptidylpeptidase IV activity

Organism Homo sapiens
Mus musculus
Rattus norvegicus

GenBank ID NC_000020
NM_139321
NP_647537
NM_139322
NP_647538
NT_011387
NW_001838652
NW_927317
AC_000152
AC_000063
AF218889
AAF72881
AAF72882
AF218910
AF218915
AL109805
CAI21876
CAI21878
AL132773
CAI22614
CAI22616
AL353193
CAH70471
CAH70472
CH471133
EAX10530
EAX10531
EAX10532
AA771958
AB011120
BAA25474
AF106861
AAD03057
AK000356
AK293010
BAF85699
AK302730
BAG63948
BC009724
AAH09724
BC101705
AAI01706
BE326239
DB240822
EC440053
O75882
Q96D99
NC_000068
NM_009730
NP_033860
NT_039207
NW_001030694
AC_000024
AF120317
AAD22476
AF120318
AL833771
CAM18035
CH466519
EDL28292
EDL28293
AB093245
BAC41429
AF116897
AAD20947
AF119821
AAD25372
AK036821
AK043073
AK146500
AK149378
AK155069
AK157888
AK162539
BAE36961
AK196642
BC141054
AAI41055
CK780901
Q3TRR6
Q8CHF0
Q9WU60
NC_005102
NM_031351
NP_112641
NW_047658
NW_001084813
AC_000071
AB049248
BAB21058
CH473949
EDL80213
EDL80214
EDL80215
EDL80216
AB038387
BAB21017
AB038388
BAB21018
Q99J86

OMIM ID 603130

Mouse chromosome position 2 73.9 cM

GO ID 0004872
0005529
0006954
0040014
0006979
0005737
0005576
0005615
0005887
0005886
0043473
0016021
0016020

Rat chromosome position 3q36

Swiss-Prot Accession O75882
Q96D99
A2AP43
Q9WU60
Q3TRR6
Q8CHF0
Q99J86
Q99PW0
A8KAE5
O60295
O95414
Q3MIT3
Q5TDA2
Q5TDA4
Q5VYW3
Q9NTQ3
Q9NTQ4
Q9NU01
Q9NZ57
Q9NZ58
Q9UC75
Q9UDF5
Q9R263
Q9WU77

Unigene ID Hs.276252
Mm.119936
Rn.53846

KEGG ID hsa:8455
mmu:11990
rno:83526

Swiss-Prot ID ATRN_RAT
ATRN_HUMAN
ATRN_MOUSE
A2AP43_MOUSE

Cell Localization Cell membrane
Secreted
Membrane
Plasma membrane

IPI ID IPI00194733
IPI00553894
IPI00027235
IPI00162735
IPI00939169
IPI00224752
IPI00828535
IPI00816518
IPI00218460

Homologene ID 22542

RGD ID 69063

MGI ID 1341628