| URN | urn:agi-llid:4161 |
|---|---|
| Connectivity | 31 |
| Name | Mc5r |
| Description | melanocortin 5 receptor |
| Notes | This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq] |
| Pathway | melanocortin system pathway |
|---|
| GO Molecular Function | signal transducer activity |
|---|---|
| hormone binding | |
| melanocortin receptor activity | |
| receptor activity | |
| G-protein coupled receptor activity |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane |
| GO Biological Process | signal transduction |
|---|---|
| G-protein signaling, coupled to cyclic nucleotide second messenger | |
| positive regulation of cAMP biosynthetic process | |
| G-protein coupled receptor protein signaling pathway |
| Ariadne Ontology | GPCR-GsCR |
|---|
| Group | GPCR-GsCR |
|---|---|
| signal transduction | |
| G-protein signaling, coupled to cyclic nucleotide second messenger | |
| positive regulation of cAMP biosynthetic process | |
| G-protein coupled receptor protein signaling pathway | |
| signal transducer activity | |
| hormone binding | |
| melanocortin receptor activity | |
| receptor activity | |
| G-protein coupled receptor activity | |
| membrane | |
| plasma membrane | |
| integral to membrane | |
| integral to plasma membrane |
| MedScan ID | 4161 |
|---|
| Hugo ID | 6933 |
|---|
| Human chromosome position | 18p11.2 |
|---|
| LocusLink ID | 4161 |
|---|---|
| 17203 | |
| 25726 |
| Alias | MC2 |
|---|---|
| melanocortin receptor 5 | |
| melanocortin-5 receptor | |
| MC5-R | |
| MC II | |
| MC5R | |
| melanocortin 5 receptor | |
| melanocortin 5 receptors |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600042 |
|---|
| Mouse chromosome position | 18 42.0 cM |
|---|
| GO ID | 0004930 |
|---|---|
| 0042562 | |
| 0004977 | |
| 0004872 | |
| 0007187 | |
| 0030819 | |
| 0005887 | |
| 0005886 | |
| 0004871 | |
| 0007186 | |
| 0007165 | |
| 0016021 | |
| 0016020 |
| Rat chromosome position | 18q12.1 |
|---|
| Swiss-Prot Accession | P33032 |
|---|---|
| Q496T0 | |
| P41149 | |
| P35345 | |
| B0YJ34 | |
| Q502V1 |
| PIR ID | JC2193 |
|---|---|
| JC5592 | |
| JN0764 |
| Unigene ID | Hs.248145 |
|---|---|
| Mm.8003 | |
| Rn.9673 |
| KEGG ID | hsa:4161 |
|---|---|
| mmu:17203 | |
| rno:25726 |
| Swiss-Prot ID | MC5R_RAT |
|---|---|
| MC5R_HUMAN | |
| Q496T0_MOUSE | |
| B0YJ34_HUMAN |
| Cell Localization | Cell membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00197625 |
|---|---|
| IPI00012299 | |
| IPI00230761 |
| Homologene ID | 4321 |
|---|
| RGD ID | 3058 |
|---|
| MGI ID | 99420 |
|---|