| URN | urn:agi-llid:23295 |
|---|---|
| Connectivity | 18 |
| Name | Mgrn1 |
| Description | mahogunin, ring finger 1 |
| Notes | Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.[supplied by OMIM] |
| Pathway | melanocortin system pathway |
|---|
| GO Molecular Function | ligase activity |
|---|---|
| metal ion binding | |
| zinc ion binding | |
| ubiquitin-protein ligase activity |
| GO Cellular Component | plasma membrane |
|---|---|
| cytoplasm | |
| early endosome | |
| nucleus |
| GO Biological Process | negative regulation of cAMP-mediated signaling |
|---|---|
| negative regulation of G-protein coupled receptor protein signaling pathway | |
| protein polyubiquitination | |
| protein monoubiquitination | |
| modification-dependent protein catabolic process | |
| endosome to lysosome transport |
| Ariadne Ontology | Ubiquitin-dependent protein degradation |
|---|---|
| Receptors |
| Group | Ubiquitin-dependent protein degradation |
|---|---|
| Receptors | |
| negative regulation of cAMP-mediated signaling | |
| negative regulation of G-protein coupled receptor protein signaling pathway | |
| protein polyubiquitination | |
| protein monoubiquitination | |
| modification-dependent protein catabolic process | |
| endosome to lysosome transport | |
| ligase activity | |
| metal ion binding | |
| zinc ion binding | |
| ubiquitin-protein ligase activity | |
| plasma membrane | |
| cytoplasm | |
| early endosome | |
| nucleus |
| MedScan ID | 23295 |
|---|
| Hugo ID | 20254 |
|---|
| Human chromosome position | 16p13.3 |
|---|
| LocusLink ID | 23295 |
|---|---|
| 17237 | |
| 302938 |
| Alias | RNF156 |
|---|---|
| KIAA0544 | |
| probable E3 ubiquitin-protein ligase MGRN1 | |
| RING finger protein 156 | |
| mahogunin RING finger protein 1 | |
| md | |
| nc | |
| N28182 | |
| mKIAA0544 | |
| 2610042J20Rik | |
| mahoganoid | |
| RGD1311862 | |
| 2610042J20 | |
| mahogunin, RING finger | |
| mahogunin, RING finger 1 | |
| mahogunin, RING finger I | |
| MGRN I | |
| MGRN1 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 607559 |
|---|
| Mouse chromosome position | 16 2.0 cM |
|---|
| GO ID | 0016874 |
|---|---|
| 0046872 | |
| 0004842 | |
| 0008270 | |
| 0008333 | |
| 0045744 | |
| 0043951 | |
| 0006513 | |
| 0005737 | |
| 0005769 | |
| 0005634 | |
| 0005886 | |
| 0000209 | |
| 0019941 |
| Rat chromosome position | 10q12 |
|---|
| Swiss-Prot Accession | O60291 |
|---|---|
| Q9D074 | |
| Q5XIQ4 | |
| Q3U5V9 | |
| Q3UDA1 | |
| Q6ZQ97 | |
| Q8BZM9 | |
| A4URL3 | |
| A4URL4 | |
| Q86W76 |
| Unigene ID | Hs.526494 |
|---|---|
| Mm.291326 | |
| Rn.15530 |
| KEGG ID | hsa:23295 |
|---|---|
| mmu:17237 | |
| rno:302938 |
| EC Number | 6.3.2.- |
|---|
| Swiss-Prot ID | MGRN1_RAT |
|---|---|
| MGRN1_MOUSE | |
| MGRN1_HUMAN |
| Cell Localization | Plasma membrane |
|---|---|
| Cytoplasm |
| IPI ID | IPI00368465 |
|---|---|
| IPI00187513 | |
| IPI00406217 | |
| IPI00460741 | |
| IPI00775949 | |
| IPI00297251 | |
| IPI00643212 | |
| IPI00915351 | |
| IPI00915359 | |
| IPI00389473 | |
| IPI00558203 |
| Homologene ID | 41020 |
|---|
| RGD ID | 1311862 |
|---|
| MGI ID | 2447670 |
|---|