| URN | urn:agi-Binding:inout-urn:agi-llid:3953:inout-urn:agi-llid:3717::unknown |
|---|---|
| References | 9 |
| Connectivity | 2 |
| Effect | unknown |
| TextRef | info:pmid/9092791#abs:7 |
|---|---|
| MedLine Reference | 9092791:6 |
| Sentence | Consistently, antibodies directed against the extracellular domain of OB-R coprecipitated Jak2. |
| Organism | Mus musculus |
| CellLineName | BaF3 |
| Tissue | hematological |
| TextRef | info:pmid/10449753#cont:71 |
|---|---|
| MedLine Reference | 10449753:10070 |
| Sentence | Previous studies demonstrated that JAK2 constitutively associates with the leptin receptor ( 19 ). |
| Organism | Mus musculus |
| Journal | PNAS |
| Journal Reference | v96 i17 p9677 |
| Journal Link | http://www.pnas.org/cgi/content/full/96/17/9677 |
| TextRef | info:pmid/10449753#body:72 |
|---|---|
| MedLine Reference | 10449753:1071 |
| Sentence | Previous studies demonstrated that JAK2 constitutively associates with the leptin receptor ( 19 ). |
| Organism | Mus musculus |
| CellLineName | 293T |
| Journal | PNAS |
| Journal Reference | v96 i17 p9677 (1999) |
| Journal Link | http://www.pnas.org/cgi/content/full/96/17/9677 |
| Source | Curated |
| TextRef | info:pmid/12734179#cont:202 |
|---|---|
| MedLine Reference | 12734179:10201 |
| Sentence | OB-R Dimerization Is Independent of JAK2? JAK2 was shown to directly bind to the OB-R, and it was suggested that this interaction may stabilize receptor dimerization ( 15 , 16 ). |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i29 p26604 |
| Journal Link | http://www.jbc.org/cgi/content/full/278/29/26604 |
| TextRef | info:pmid/12734179#body:34 |
|---|---|
| MedLine Reference | 12734179:1033 |
| Sentence | OB-R is constitutively associated with the Janus kinase 2 (JAK2). 1 JAK2 binding to the receptor is critical for OB-R signaling and has been proposed to be involved in the stabilization of receptor dimers ( 15 , 16 ). |
| Tissue | blood brain barrier |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i29 p26604 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/29/26604 |
| Source | Curated |
| TextRef | info:pmid/8608603 |
|---|---|
| MedLine Reference | 8608603 |
| Source | Entrez Gene |
| TextRef | info:pmid/1 |
|---|---|
| MedLine Reference | 1f48ea783a985c8478758d70e810b11d |
| Organism | Mus musculus |
| CellLineName | BaF3 |
| Tissue | hematological |
| Source | RGD modified |
| MedLine Reference | a97cb176bc67503f518b91cb8064438e |
|---|---|
| Organism | Mus musculus |
| CellLineName | BaF3 |
| Tissue | hematological |
| Source | ResNet |
| TextRef | info:pmid/3357402 |
|---|---|
| MedLine Reference | 3357402d6c357f4243f56f78dba48512 |
| Organism | Mus musculus |
| CellLineName | BaF3 |
| Tissue | hematological |