| URN | urn:agi-ProtModification:inout-urn:agi-llid:3717:out-urn:agi-llid:6774::positive:phosphorylation |
|---|---|
| References | 92 |
| Connectivity | 2 |
| Effect | positive |
| Mechanism | phosphorylation |
| Original # of References | 48 |
| TextRef | info:pmid/18718905#abs:3 |
|---|---|
| PubYear | 2008 |
| MedlineTA | J Biol Chem |
| MedLine Reference | 18718905:2 |
| Sentence | JAK2 also phosphorylates LEPRb, STAT3, and multiple other downstream molecules. |
| TextRef | info:pmid/15151905#abs:6 |
|---|---|
| MedLine Reference | 15151905:5 |
| Sentence | IL-6 treatment increased the phosphorylation of JAK2, an upstream activator of STAT3. |
| TextRef | info:pmid/10891587#abs:6 |
|---|---|
| MedLine Reference | 10891587:5 |
| Sentence | The PSD fraction also had a janus kinase 2 (Jak2)-like molecule, Jak2, believed to phosphorylate Stat3. |
| TextRef | info:pmid/20530874#abs:4 |
|---|---|
| PubYear | 2010 |
| MedlineTA | J Clin Invest |
| MedLine Reference | 20530874:3 |
| Sentence | Here we have shown that hepcidin-activated Jak2 also phosphorylates the transcription factor Stat3, resulting in a transcriptional response. |
| TextRef | info:pmid/19153190#abs:7 |
|---|---|
| PubYear | 2009 |
| MedlineTA | J Mol Endocrinol |
| MedLine Reference | 19153190:6 |
| Sentence | G-Gly stimulated JAK2 phosphorylation and kinase activity and JAK2-dependent STAT3 phosphorylation and transcriptional activity. |
| CellLineName | oe33 |
| TextRef | info:pmid/16025117#abs:3 |
|---|---|
| PubYear | 2005 |
| MedlineTA | Nat Immunol |
| MedLine Reference | 16025117:2 |
| Sentence | STAT3 was phosphorylated by the tyrosine kinase Jak2 that was recruited to the alpha7 subunit of the nicotinic acetylcholine receptor. |
| CellType | Macrophages, Peritoneal |
| TextRef | info:pmid/15688010#abs:9 |
|---|---|
| MedLine Reference | 15688010:8 |
| Sentence | Tkip also inhibited constitutive (DU145) and IL-6-induced (LNCaP) activation of STAT3, consistent with the fact that STAT3 activation is mediated by JAK2. |
| TextRef | info:pmid/15156153#abs:3 |
|---|---|
| MedLine Reference | 15156153:2 |
| Sentence | Hes proteins associate with JAK2 and STAT3, and facilitate complex formation between JAK2 and STAT3, thus promoting STAT3 phosphorylation and activation. |
| TextRef | info:pmid/18930836#abs:4 |
|---|---|
| MedLine Reference | 18930836:3 |
| Sentence | These changes were accompanied by an increase in alpha2, alpha6 and beta1 integrin subunits and activation of JAK2 and STAT3 signalling which was suppressed by a specific JAK2 inhibitor. |
| TextRef | info:pmid/9525481#abs:9 |
|---|---|
| MedLine Reference | 9525481:8 |
| Sentence | These results raise the possibility that Jak-2 and Tyk-2 are both activated by v-Src, thereby contributing to the constitutive activation of STAT3 in the v-Src-transformed cells. |
| TextRef | info:pmid/12949733#abs:11 |
|---|---|
| MedLine Reference | 12949733:10 |
| Sentence | Blocking of the STAT3 upstream activator Janus kinase 2 by tyrphostin also resulted in growth arrest because of delayed G(1)/S-phase progression and increased expression of p21(WAF1). |
| TextRef | info:pmid/11708838#abs:5 |
|---|---|
| MedLine Reference | 11708838:4 |
| Sentence | The results demonstrated extensive phosphorylation of JAK2 and STAT3 in the IPC hearts which was almost completely abolished by an inhibitor of JAK2, AG490. |
| TextRef | info:pmid/16871275#abs:8 |
|---|---|
| PubYear | 2006 |
| MedlineTA | Leukemia |
| MedLine Reference | 16871275:7 |
| Sentence | These results suggest that mutant JAK2 contributes to myelofibrosis with myeloid metaplasia pathogenesis by constitutively phosphorylating STAT3 and diminishing myeloid cell apoptosis. |
| TextMods | 54: 'MMM ' -> 'myelofibrosis with myeloid metaplasia ' |
| CellType | Neutrophils |
| TextRef | info:pmid/16306356#abs:3 |
|---|---|
| PubYear | 2005 |
| MedlineTA | Diabetes |
| MedLine Reference | 16306356:2 |
| Sentence | Leptin stimulation led to janus kinase 2-dependent phosphorylation and nuclear translocation of the transcription factors signal transducer and activator of transcription 3 and STAT5b in INS-1 beta-cells. |
| TextMods | 39: '(JAK)' -> '' 171: '(STAT)' -> '' |
| CellType | Insulin-Secreting Cells |
| TextRef | info:pmid/15155836#abs:7 |
|---|---|
| MedLine Reference | 15155836:6 |
| Sentence | Inhibition of c-Src and Janus kinase 2 and 3 activities abolished STAT3 activation induced by Galpha14QL, but no physical association between Galpha14QL and c-Src could be detected by coimmunoprecipitation. |
| TextRef | info:pmid/12393423#abs:5 |
|---|---|
| MedLine Reference | 12393423:4 |
| Sentence | G-CSF-induced up-regulation of cIAP2 mRNA and protein, phosphorylation of signal transducer and activator of transcription 3 (STAT3), and the antiapoptotic effects were inhibited by pretreatment of cells with AG490, a specific inhibitor of Janus kinase 2 (JAK2). |
| TextRef | info:pmid/15650183#abs:7 |
|---|---|
| MedLine Reference | 15650183:6 |
| Sentence | Using a series of inhibitors and dominant negative mutants, we show that HCV-induced activation of STAT-3 is mediated by oxidative stress and influenced by the activation of cellular kinases, including p38 mitogen-activated protein kinase, JNK, JAK-2, and Src. |
| TextRef | info:pmid/16934228#abs:5 |
|---|---|
| PubYear | 2006 |
| MedlineTA | Biochem Pharmacol |
| MedLine Reference | 16934228:4 |
| Sentence | Activation of Jak2 and Stat3 were monitored by Western blot analysis for phosphorylated Jak2 and phosphorylated Stat3. mRNA expression and protein level of IL-1beta were determined by reverse transcription-polymerase chain reaction and enzyme-linked immunosorbant assay . |
| CellLineName | AR42j |
| TextMods | 232: '(RT-PCR) ' -> '' 270: '(ELISA)' -> '' |
| Organ | Pancreas |
| TextRef | info:pmid/20415779#abs:5 |
|---|---|
| PubYear | 2010 |
| MedlineTA | Scand J Immunol |
| MedLine Reference | 20415779:4 |
| Sentence | Interleukin-23 binding to an Interleukin-23 receptor expressed on dendritic cells, macrophages and monocytes triggers the activation of Jak2 and Tyk2, which in turn phosphorylates STAT1, STAT3, STAT4 and STAT5 as well as induce formation of STAT3-STAT4 heterodimers. |
| TextMods | 0: 'IL-23 ' -> 'Interleukin-23 ' 29: 'IL-23 ' -> 'Interleukin-23 ' |
| CellType | Macrophages |
| TextRef | info:pmid/7588209#abs:7 |
|---|---|
| PubYear | 1995 |
| MedlineTA | Endocrinology |
| MedLine Reference | 7588209:6 |
| Sentence | Dexamethasone does not inhibit induction of tyrosyl phosphorylation of ERK proteins by epidermal growth factor or phorbol myristate acetate, nor does it block induction of tyrosyl phosphorylation of Stat3/APRF by leukemia inhibitory factor or interleukin-6, or induction of JAK2 by leukemia inhibitory factor or interferon-gamma. |
| CellType | Fibroblasts |
| TextRef | info:pmid/10545526#body:243 |
|---|---|
| PubYear | 1999 |
| MedlineTA | J Clin Invest |
| MedLine Reference | 10545526:1242 |
| Sentence | JAK2 tyrosine phosphorylates itself, as well as gp130 and STAT3. |
| CellType | Corticotrophs |
| TextRef | info:pmid/12907755#body:48 |
|---|---|
| PubYear | 2003 |
| MedlineTA | Mol Endocrinol |
| MedLine Reference | 12907755:1047 |
| Sentence | Activated Jak2 undergoes autotyrosine phosphorylation and phosphorylates GH receptor, STAT3, -5a and -5b (20, 21, 22). |
| TextMods | 73: 'GHR' -> 'GH receptor' |
| TextRef | info:pmid/14617636#body:204 |
|---|---|
| PubYear | 2004 |
| MedlineTA | J Biol Chem |
| MedLine Reference | 14617636:1203 |
| Sentence | Our previous data suggests that STAT-3 is phosphorylated by JAK-2 at these later time points (33). |
| CellType | Endothelial Cells |
| Organ | Umbilical vein |
| Organism | Homo sapiens |
| TextRef | info:pmid/9759879#body:40 |
|---|---|
| PubYear | 1998 |
| MedlineTA | J Immunol |
| MedLine Reference | 9759879:1039 |
| Sentence | A very early event is tyrosine phosphorylation of the 92-kDa STAT3 protein by JAK1 or JAK2 kinase (7, 8). |
| CellType | Hepatocytes |
| TextRef | info:pmid/17565041#body:302 |
|---|---|
| PubYear | 2007 |
| MedlineTA | Mol Endocrinol |
| MedLine Reference | 17565041:1301 |
| Sentence | One explanation for these interesting data is that STAT3 is already maximally phosphorylated by JAK2Y813F or by JAK2 at endogenous levels of SH2B1. |
| TextRef | info:pmid/16007267#body:170 |
|---|---|
| PubYear | 2005 |
| MedlineTA | J Clin Invest |
| MedLine Reference | 16007267:1169 |
| Sentence | STAT3 is phosphorylated by the JAK2 kinase, which is recruited to the intracellular domains of the G-CSF receptor upon ligand binding. |
| CellType | Neurons |
| TextRef | info:pmid/11751408#body:255 |
|---|---|
| PubYear | 2001 |
| MedlineTA | Cancer Res |
| MedLine Reference | 11751408:1254 |
| Sentence | After the treatment of cells with IL-6, gp130 dimerizes, and the gp130-associated JAK1 and JAK2 phosphorylate STAT3 (14 , 15) . |
| TextRef | info:pmid/15284024#body:244 |
|---|---|
| PubYear | 2004 |
| MedlineTA | Am J Physiol Gastrointest Liver Physiol |
| MedLine Reference | 15284024:1243 |
| Sentence | In interferon-γ signaling, activation of JAK1 and JAK2 is known to phosphorylate STAT1 as well as STAT3 on tyrosine residues. |
| TextMods | 3: 'IFN' -> 'interferon' |
| Tissue | Endothelium |
| TextRef | info:pmid/17235396#body:61 |
|---|---|
| PubYear | 2007 |
| MedlineTA | J Clin Invest |
| MedLine Reference | 17235396:1060 |
| Sentence | Activated JAK2 phosphorylates and activates downstream signaling molecules, including STAT3, insulin receptor substrate 1 (IRS1) and IRS2 (19). |
| Organ | hypothalamus |
| TextRef | info:pmid/17898043#body:180 |
|---|---|
| PubYear | 2007 |
| MedlineTA | Am J Physiol Renal Physiol |
| MedLine Reference | 17898043:1179 |
| Sentence | Basal phospho-STAT3 was unaffected by AG490 in wild-type cells, suggesting that STAT3 is phosphorylated by a kinase other than JAK2 in the basal state. |
| CellLineName | MCF7 |
| TextRef | info:pmid/11970899#body:125 |
|---|---|
| PubYear | 2002 |
| MedlineTA | Dev Cell |
| MedLine Reference | 11970899:1124 |
| Sentence | Binding of leptin activates Jak2, which in turn phosphorylates the receptor and the signal transducers and activators of transcription 3 (Stat3) protein. |
| Organ | hypothalamus |
| TextRef | info:pmid/15150111#body:330 |
|---|---|
| PubYear | 2004 |
| MedlineTA | Cancer Res |
| MedLine Reference | 15150111:1329 |
| Sentence | In this situation, STAT3 may be phosphorylated by one or more Janus-activated kinases, such as JAK2 and TYK2, which were present and activated in focal adhesions. |
| TextMods | 62: 'JAKs' -> 'Janus-activated kinases' |
| Tissue | Serum |
| TextRef | info:pmid/15522880#body:63 |
|---|---|
| PubYear | 2005 |
| MedlineTA | J Biol Chem |
| MedLine Reference | 15522880:1062 |
| Sentence | Upon binding to its receptor, Interleukin-12 activates Janus family kinases Tyk2 and Jak2, which then phosphorylate the tyrosine residues of Stat3 and Stat4 (10). |
| TextMods | 30: 'IL' -> 'Interleukin' |
| CellType | T-Lymphocytes |
| TextRef | info:pmid/18716208#body:136 |
|---|---|
| PubYear | 2008 |
| MedlineTA | J Neurosci |
| MedLine Reference | 18716208:1135 |
| Sentence | janus kinase 2 then phosphorylates Y205 of STAT3, which causes it to homodimerize or heterodimerize and be translocated to the nucleus in which it binds DNA and stimulates transcription. |
| TextMods | 0: 'JAK2 ' -> 'janus kinase 2 ' |
| Organ | Hippocampus |
| TextRef | info:pmid/14576184#body:72 |
|---|---|
| PubYear | 2004 |
| MedlineTA | Endocrinology |
| MedLine Reference | 14576184:1071 |
| Sentence | The LIF receptor-gp130 complex activates Janus kinase 2 (JAK2) by tyrosine autophosphorylation, which phosphorylates signal transducer and activator of transcription-3 (STAT-3). |
| CellType | Corticotrophs |
| TextRef | info:pmid/18079357#body:53 |
|---|---|
| PubYear | 2008 |
| MedlineTA | J Pharmacol Exp Ther |
| MedLine Reference | 18079357:1052 |
| Sentence | Jak2 also phosphorylates signal transducer and activator of transcription 5 and Stat3 (Kirito et al., 1997[Go]), which then translocate to the nucleus to act as transcription factors and mediate Erythropoietin effects. |
| TextMods | 201: 'Epo ' -> 'Erythropoietin ' 74: '(Stat)' -> '' |
| CellType | Erythrocytes |
| TextRef | info:pmid/15604114#body:62 |
|---|---|
| PubYear | 2005 |
| MedlineTA | Mol Endocrinol |
| MedLine Reference | 15604114:1061 |
| Sentence | Phosphorylated Tyr1138 on LRb recruits the latent cytoplasmic transcription factor STAT3, which is then phosphorylated by Jak2 to mediate the translocation of STAT3 into the nucleus to activate gene transcription (9, 12, 13, 14). |
| CellType | Neurons |
| Organ | hypothalamus |
| TextRef | info:pmid/17204555#body:61 |
|---|---|
| PubYear | 2007 |
| MedlineTA | Endocrinology |
| MedLine Reference | 17204555:1060 |
| Sentence | Leptin or GH stimulates the activation of JAK2, which subsequently phosphorylates multiple substrates, including insulin receptor substrate -1, IRS2, signal transducer and activator of transcription -3, and STAT5 (12, 13, 14, 15, 16, 17, 18, 19, 20). |
| TextMods | 140: '(IRS)' -> '' 199: '(STAT)' -> '' |
| Organ | hypothalamus |
| TextRef | info:pmid/10465259#body:40 |
|---|---|
| PubYear | 1999 |
| MedlineTA | Endocrinology |
| MedLine Reference | 10465259:1039 |
| Sentence | In hGH receptor and human PRL receptor, an active 1:2 complex formation is followed by activation of the intracellular tyrosine kinase JAK2, which then phosphorylates signal transducer and activator of transcription proteins such as Stat1, 3, and 5 (14, 15, 16). |
| TextMods | 3: 'hGHR ' -> 'hGH receptor ' 20: 'hPRLR' -> 'human PRL receptor' 216: '(Stat) ' -> '' |
| TextRef | info:pmid/19494234#body:74 |
|---|---|
| PubYear | 2009 |
| MedlineTA | Am J Physiol Cell Physiol |
| MedLine Reference | 19494234:1073 |
| Sentence | Second, STAT proteins (including STAT-1, -3, and -5) (12) are phosphorylated by Jak2, which then form homo- or heterodimers and translocate into the nucleus where they bind to specific response elements (GAS sites) in the promoters of target genes (10, 12, 54). |
| Organ | Mammary Gland |
| TextRef | info:pmid/19179437#body:86 |
|---|---|
| PubYear | 2009 |
| MedlineTA | Endocrinology |
| MedLine Reference | 19179437:1085 |
| Sentence | Moreover, inhibition of Janus kinase-2, responsible for the leptin-dependent phosphorylation of signal transducer and activator of transcription -3, within GnRH neurons abolishes the effects of leptin on GnRH neuronal activity (31). |
| TextMods | 145: '(STAT)' -> '' |
| CellType | Neurons |
| TextRef | info:pmid/15466267#body:58 |
|---|---|
| PubYear | 2004 |
| MedlineTA | J Am Soc Nephrol |
| MedLine Reference | 15466267:1057 |
| Sentence | The activated JAK2 in turn phosphorylates the growth hormone receptor, creating binding sites for selective members of the signal transducers and activators of transcription family of proteins, namely STAT1, STAT3, and STAT5a, and STAT5b, which are then phosphorylated by JAK2 (14,15). |
| TextMods | 46: 'GHR' -> 'growth hormone receptor' 123: 'STAT ' -> 'signal transducers and activators of transcription ' |
| Tissue | Skeletal muscle |
| TextRef | info:pmid/9794437#body:267 |
|---|---|
| PubYear | 1998 |
| MedlineTA | J Immunol |
| MedLine Reference | 9794437:1266 |
| Sentence | One possible site of genistein action is OSM activation of tyrosine kinases, Janus kinases (Tyk-1, Jak-1, Jak-2) (57) that phosphorylate STAT-1 and STAT-3 and whose homo- or heterodimers (58) in turn are translocated to the nucleus to activate the target genes, such as TIMP-3 and TIMP-1. |
| CellType | Chondrocytes |
| TextRef | info:pmid/17717190#body:169 |
|---|---|
| PubYear | 2007 |
| MedlineTA | J Pharmacol Exp Ther |
| MedLine Reference | 17717190:1168 |
| Sentence | Janus kinase 2 is also able to phosphorylate and activate the downstream anti apoptotic targets signal transducers and activators of transcription (STAT3 and STAT5) or various kinases (p38 or p42/44 mitogen-activated protein kinases and protein kinase C) with anti apoptotic or antinecrotic properties. |
| CellType | Erythrocytes |
| TextRef | info:pmid/12492118#body:87 |
|---|---|
| PubYear | 2002 |
| MedlineTA | Mol Cancer Ther |
| MedLine Reference | 12492118:1086 |
| Sentence | To characterize inhibition of constitutive or IL-6-induced growth signaling by As2O3, immunoblotting was also done with anti-phosphorylated JAK1, anti-phosphorylated JAK2 (Biosource International, Camarillo, CA), anti-phosphorylated STAT3, anti-phosphorylated ERK (Santa Cruz), or anti-phosphorylated Akt (Cell Signaling Technology) antibodies, as well as antibodies against their nonphosphorylated counterparts. |
| TextRef | info:pmid/19897720#body:103 |
|---|---|
| PubYear | 2009 |
| MedlineTA | Proc Natl Acad Sci U S A |
| MedLine Reference | 19897720:1102 |
| Sentence | Moreover, it correlated with a clear decrease in the cellular levels of both total and phosphorylated STAT3 (Fig. 3E), most likely as a consequence of reduced cytokine receptor-induced signals that control the JAK2-dependent phosphorylation of STAT3 and the subsequent P-STAT3- and nuclear factor-κB-dependent feed-forward control of STAT3 gene expression in these cells (19). |
| TextMods | 282: 'NF-κB' -> 'nuclear factor-κB' |
| CellType | activated B-lymphocytes |
| TextRef | info:pmid/17897356#body:258 |
|---|---|
| PubYear | 2007 |
| MedlineTA | J Neurochem |
| MedLine Reference | 17897356:1257 |
| Sentence | Fig. 6 Analysis of immunofluorescent colocalization of glial fibrillary acidic protein (GFAP) with leukemia inhibitory factor (LIF), ciliary neurotropic factor (CNTF), phosphorylated-Janus kinase (p-JAK2), p-phosphorylated-signal transducers and activators of transcription (STAT1), p-STAT3, or nestin in hippocampus sections from scrapie-infected brains. |
| Organ | Hippocampus |
| TextRef | info:pmid/16514095#body:100 |
|---|---|
| PubYear | 2006 |
| MedlineTA | Stroke |
| MedLine Reference | 16514095:1099 |
| Sentence | Expanding evidence from recent studies clearly shows that G-CSF exerts an anti apoptotic effect on neurons both in vivo and in vitro.9,11-13 G-CSF has been reported to protect cortical neurons in vitro against camptothecin-induced and NO-induced apoptosis by reducing caspase-3 and poly-ADP ribose polymerase cleavage.13 G-CSF exposure results in rapid STAT3 phosphorylation by Janus kinase2 kinase in neurons, which is inhibited by AG 490, a specific inhibitor of Janus kinase2 (Figure 2). |
| TextMods | 377: 'JAK' -> 'Janus kinase' 464: 'JAK' -> 'Janus kinase' |
| CellType | Neurons |
| Organ | Cerebral cortex |
| TextRef | info:pmid/15292206#body:264 |
|---|---|
| MedLine Reference | 15292206:1263 |
| Sentence | Jak1, Jak2, and Tyk2 are reported to activate Stat3 independently. |
| TextRef | info:pmid/11756159#body:218 |
|---|---|
| MedLine Reference | 11756159:1217 |
| Sentence | This result indicates that Jak2 activated Stat1 and Stat3 in response to EPO. |
| TextRef | info:pmid/11940572#body:219 |
|---|---|
| MedLine Reference | 11940572:1218 |
| Sentence | Transfection of JAK2 DN reduces Stat3alpha-mediated transcription by ErbB-2 V E by nearly 70% (Fig. 9 ). |
| TextRef | info:pmid/11940567#body:314 |
|---|---|
| MedLine Reference | 11940567:1313 |
| Sentence | Prolonged (60 min) phosphorylation of STAT-3 in PP1-pretreated cells suggests that JAK-2 may be involved in STAT-3 activation along with Src as noted previously. |
| TextRef | info:pmid/12672794#body:202 |
|---|---|
| MedLine Reference | 12672794:1201 |
| Sentence | Phospho-JAK2 Kinase Up-regulates Phospho-STAT3, Which Translocates Quickly into the Nucleus??? We next examined which STATs were downstream of the H-2g-induced endothelial JAK2 pathway. |
| TextRef | info:pmid/11445068#abs:2 |
|---|---|
| MedLine Reference | 11445068:1 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/9872331#abs:4 |
|---|---|
| MedLine Reference | 9872331:3 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/15284024#abs:6 |
|---|---|
| MedLine Reference | 15284024:5 |
| Source | Ariadne Signaling Pathways |
| MedLine Reference | 0:53836266 |
|---|---|
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14729671#abs:6 |
|---|---|
| MedLine Reference | 14729671:5 |
| CellLineName | C2C12 |
| CellType | myotube |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11163768#abs:4 |
|---|---|
| MedLine Reference | 11163768:3 |
| CellLineName | DU 145 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/10856262#body:136 |
|---|---|
| MedLine Reference | 10856262:1135 |
| CellType | myocyte |
| Organ | Heart |
| Journal | Hypertension |
| Journal Reference | v35 i6 p1191 (2000) |
| Journal Link | http://hyper.ahajournals.org/cgi/content/full/35/6/1191 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/12672794#body:215 |
|---|---|
| MedLine Reference | 12672794:1214 |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i24 p21869 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/24/21869 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/9305939#body:107 |
|---|---|
| MedLine Reference | 9305939:1106 |
| Journal | J. Biol. Chem |
| Journal Reference | v272 i39 p24684 (1997) |
| Journal Link | http://www.jbc.org/cgi/content/full/272/39/24684 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/9119818#body:27 |
|---|---|
| MedLine Reference | 9119818:1026 |
| Journal | J. Biol. Chem |
| Journal Reference | v272 i12 p7567 (1997) |
| Journal Link | http://www.jbc.org/cgi/content/full/272/12/7567 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/12529425#body:46 |
|---|---|
| MedLine Reference | 12529425:1045 |
| Journal | Mol. Biol. Cell |
| Journal Reference | v14 i1 p40 (2003) |
| Journal Link | http://www.molbiolcell.org/cgi/content/full/14/1/40 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/15143188#body:171 |
|---|---|
| MedLine Reference | 15143188:1170 |
| Journal | Mol. Cell. Biol |
| Journal Reference | v24 i11 p4968 (2004) |
| Journal Link | http://mcb.asm.org/cgi/content/full/24/11/4968 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11846786#body:160 |
|---|---|
| MedLine Reference | 11846786:1159 |
| Journal | Eur. J. Biochem |
| Journal Reference | v269 i3 p850 (2002) |
| Journal Link | http://www.ejbiochem.org/cgi/content/full/269/3/850 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11751408#body:231 |
|---|---|
| MedLine Reference | 11751408:1230 |
| Journal | Cancer Res |
| Journal Reference | v61 i24 p8851 (2001) |
| Journal Link | http://cancerres.aacrjournals.org/cgi/content/full/61/24/8851 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11856732#body:29 |
|---|---|
| MedLine Reference | 11856732:1028 |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i18 p16211 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/18/16211 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/12738762#body:133 |
|---|---|
| MedLine Reference | 12738762:1132 |
| Tissue | muscle |
| Journal | Mol. Endocrin |
| Journal Reference | v17 i8 p1580 (2003) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/17/8/1580 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/15292206#body:266 |
|---|---|
| MedLine Reference | 15292206:1265 |
| Tissue | epithelia |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i42 p44093 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/42/44093 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/9864141#body:134 |
|---|---|
| MedLine Reference | 9864141:1133 |
| CellLineName | M1 |
| Journal | Blood |
| Journal Reference | v93 i1 p15 (1999) |
| Journal Link | http://www.bloodjournal.org/cgi/content/full/93/1/15 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11756159#body:119 |
|---|---|
| MedLine Reference | 11756159:1118 |
| CellLineName | UT7/EPO |
| Journal | Blood |
| Journal Reference | v99 i1 p102 (2002) |
| Journal Link | http://www.bloodjournal.org/cgi/content/full/99/1/102 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11940567#body:324 |
|---|---|
| MedLine Reference | 11940567:1323 |
| CellLineName | A431 |
| CellType | platelet |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i24 p21237 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/24/21237 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11821424#body:309 |
|---|---|
| MedLine Reference | 11821424:1308 |
| CellLineName | HC11 |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i16 p14020 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/16/14020 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/15078989#body:46 |
|---|---|
| MedLine Reference | 15078989:1045 |
| CellLineName | A431 |
| Tissue | cervix |
| Journal | Mol. Cancer Ther |
| Journal Reference | v3 i4 p459 (2004) |
| Journal Link | http://mct.aacrjournals.org/cgi/content/full/3/4/459 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/12595539#body:220 |
|---|---|
| MedLine Reference | 12595539:1219 |
| CellType | myocyte |
| Organ | ventricle |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i18 p16304 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/18/16304 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/9211920#body:224 |
|---|---|
| MedLine Reference | 9211920:1223 |
| Organ | Liver |
| Journal | J. Biol. Chem |
| Journal Reference | v272 i28 p17694 (1997) |
| Journal Link | http://www.jbc.org/cgi/content/full/272/28/17694 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14634121#body:221 |
|---|---|
| MedLine Reference | 14634121:1220 |
| Tissue | microglia |
| Organ | Brain |
| Journal | J. Immunol |
| Journal Reference | v171 i11 p6072 (2003) |
| Journal Link | http://www.jimmunol.org/cgi/content/full/171/11/6072 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14576184#body:41 |
|---|---|
| MedLine Reference | 14576184:1040 |
| Tissue | epithelia |
| Organ | pituitar |
| Journal | Endocrinology |
| Journal Reference | v145 i2 p867 (2004) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/145/2/867 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11278353#body:200 |
|---|---|
| MedLine Reference | 11278353:1199 |
| Journal | J. Biol. Chem |
| Journal Reference | v276 i24 p21004 (2001) |
| Journal Link | http://www.jbc.org/cgi/content/full/276/24/21004 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/12244095#body:262 |
|---|---|
| MedLine Reference | 12244095:1261 |
| CellType | fibroblast |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i47 p45680 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/47/45680 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11481471#body:167 |
|---|---|
| MedLine Reference | 11481471:1166 |
| CellType | macrophage |
| Journal | PNAS |
| Journal Reference | v98 i16 p9050 (2001) |
| Journal Link | http://www.pnas.org/cgi/content/full/98/16/9050 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14749471#body:249 |
|---|---|
| MedLine Reference | 14749471:1248 |
| Journal | Mol. Cancer Ther |
| Journal Reference | v3 i1 p11 (2004) |
| Journal Link | http://mct.aacrjournals.org/cgi/content/full/3/1/11 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11231909#body:82 |
|---|---|
| MedLine Reference | 11231909:1081 |
| Journal | ATVB |
| Journal Reference | v21 i3 p321 (2001) |
| Journal Link | http://atvb.ahajournals.org/cgi/content/full/21/3/321 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/10747872#body:246 |
|---|---|
| MedLine Reference | 10747872:1245 |
| Journal | J. Biol. Chem |
| Journal Reference | v275 i20 p15099 (2000) |
| Journal Link | http://www.jbc.org/cgi/content/full/275/20/15099 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14736711#body:14 |
|---|---|
| MedLine Reference | 14736711:1013 |
| CellType | monocyte |
| Journal | Cell Phys |
| Journal Reference | v286 i6 pC1302 (2004) |
| Journal Link | http://ajpcell.physiology.org/cgi/content/full/286/6/C1302 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/14551213#body:22 |
|---|---|
| MedLine Reference | 14551213:1021 |
| CellLineName | 293 |
| Organ | Kidney |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i52 p52154 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/52/52154 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/10385399#body:26 |
|---|---|
| MedLine Reference | 10385399:1025 |
| CellLineName | C6 |
| Journal | Endocrinology |
| Journal Reference | v140 i7 p3073 (1999) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/140/7/3073 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/11940572#body:192 |
|---|---|
| MedLine Reference | 11940572:1191 |
| CellLineName | NIH 3T3 |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i41 p38486 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/41/38486 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/10391929#body:26 |
|---|---|
| MedLine Reference | 10391929:1025 |
| CellLineName | VSMCs |
| Tissue | smooth muscle |
| Journal | J. Biol. Chem |
| Journal Reference | v274 i28 p19846 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/28/19846 |
| Source | Ariadne Signaling Pathways |
| TextRef | info:pmid/15143188#body:140 |
|---|---|
| MedLine Reference | 15143188:1139 |
| MedLine Reference | abdb84f4bb5a7492db7a62ec305e08c6 |
|---|---|
| Source | GO component |